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Project Details

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Universitätsklinikum Münster
Klinik für Anästhesiologie,
operative Intensivmedizin und Schmerztherapie

Address Albert-Schweitzer-Campus 1
48149 Münster
Deutschland

GERiT This institution in GERiT

48149 Münster

Projects

Research Fellowships
- Completed projects
Research Grants
- Current projects
- Completed projects
Independent Junior Research Groups
- Completed projects
  - Mechanisms of neutrophil activation in inflammation
    (Applicant Zarbock, Alexander )
Heisenberg Professorships
- Completed projects
  - Molecular mechanisms of leukocyte activation and recruitment during systemic inflammatory responses (SIRS and sepsis)
    (Applicant Zarbock, Alexander )
Clinical Trials
- Current projects
- Completed projects
  - Regionale citrate versus systemic heparin anticoagulation for continuous renal replacement therapy in critically ill patients with acute kidney injury (RICH-Trial)
    (Applicant Zarbock, Alexander )
Clinical Research Units
- Current projects
  - Coordination Funds
    (Applicant Zarbock, Alexander )
  - Effects of the Alarmin S100A8/A9 on the Platelet and Neutrophil Response during Pulmonary Inflammation
    (Applicants Rossaint, Jan ; Vogl, Ph.D., Thomas )
  - Immune System variables in healthy subjects and during systemic inflammation
    (Applicants Klotz, Luisa ; Rossaint, Jan ; Roth, Johannes )
  - KFO 342: Organ Dysfuncion During Systemic Inflammation
    (Spokesperson Zarbock, Alexander )
  - Multidimensional profiling of novel mediators and therapeutic targets in AKI during systemic inflammation.
    (Applicants Meersch, Melanie ; Pavenstädt, Hermann )
  - Role of Neuropilin-1 on Lung Macrophages during Pulmonary Inflammation
    (Applicants Eble, Johannes Andreas ; Zarbock, Alexander )
  - The Renin-Angiotensin II Axis: a Novel Target for the Treatment of Acute Kidney Injury
    (Applicants Schäfers, Michael ; Zarbock, Alexander )
  - The Role of Bacteria-derived Outer-Membrane-Vesicles (OMVs) in the Induction of Systemic Inflammation and Organ Damage
    (Applicants Dersch, Petra ; Margraf, Andreas )
Collaborative Research Centres
- Current projects
  - Imaging of immune cell dynamics and host-pathogen interactions in gut-associated lymphoid tissue during Yersinia pseudotuberculosis infections
    (Project Heads Dersch, Petra ; Rossaint, Jan )
  - Mechanisms of NET formation during sterile and bacterial inflammation
    (Project Heads Block, Helena ; Zarbock, Alexander )
- Completed projects
  - Staphylococcus aureus Infektionen des vaskulären Kompartments: Interaktion zwischen Bakterien, Thrombozyten und Endothel
    (Project Heads Heilmann, Christine ; Kehrel, Beate Elisabeth ; Peters, Georg )
  - The role of intracellular calcium regulators in integrin activation and leukocyte recruitment
    (Project Heads Cappenberg, Anika ; Zarbock, Alexander )
Research Units
- Completed projects
  - Central processing of inflammatory, neuropathic and uraemic pruritus
    (Applicants Pfleiderer, Bettina ; Pogatzki-Zahn, Esther )
WBP Fellowship
- Current projects
  - Tumor-innervating neurons modulate anti-cancer immunity
    (Applicant Brabenec, Laura )
- Completed projects
  - The role, interplay and phenotypic changes of platelets in inflammation mediated organ damage.
    (Applicant Margraf, Andreas )
CRC/Transregios
- Current projects
  - The role of the phosphatases CD45 and CD148 in the onset and progression of rheumatoid arthritis
    (Project Head Zarbock, Alexander )
- Completed projects
  - Immune regulation at the CNS barriers and in the CNS: role of immune cell trafficking
    (Project Heads Schwab, Ph.D., Nicholas ; Zarbock, Alexander )
Priority Programmes
- Current projects
  - The influence of NO releasing and DNase functional surface on platelet activation and resulting NET formation in oxygenator thrombosis – an in vivo and in vitro evaluation
    (Applicants Madrahimov, Nodir ; Rossaint, Rolf ; Singh, Ph.D., Smriti )
- Completed projects
  - Microfluidic cell sorting - A new approach towards implantable artificial lungs
    (Applicants Rossaint, Rolf ; Rossaint, Jan ; Wessling, Matthias )

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