Leibniz-Institut für Virologie (LIV)
Address
Martinistraße 52
20251 Hamburg
Deutschland
GERiT
This institution in GERiT
20251 Hamburg
Projects
Research Units
Current projects
FOR 5200: Disrupt - Evade - Exploit: Gene expression and host response programming in DNA virus infection (DEEP-DV)
(Spokesperson
Brinkmann, Melanie
)
Herpesvirus-Chromatin-Programmierung während der De-Novo-Infektion
(Applicants
Grundhoff, Adam
;
Viejo-Borbolla, Abel
)
Completed projects
Funktionelle Charakterisierung EBNA2-assoziierter zellulärer Proteine
(Applicant
Dobner, Thomas
)
Research Grants
Current projects
Mechanisms and Consequences of Human Cytomegalovirus-Induced Cell Fusion
(Applicant
Brune, Wolfram
)
Completed projects
Activation and inhibition of the IRE1-mediated unfolded protein response by cytomegalovirus
(Applicant
Brune, Wolfram
)
Aktivitätskontrolle und zelluläre Funktionen von Transglutaminasen
(Applicant
Lother, Heinz
)
Analysis off tumor progression and metastasis in transgenic mouse models for SV40 induced mammary carcinogenesis
(Applicants
Deppert, Wolfgang
;
Schumacher, Udo
)
Analysis of interferon-induced inhibition of hepatitis B virus in vitro
(Applicant
Will, Hans
)
Deciphering the molecular mechanisms of SV40-induced polyploidization
(Applicant
Dornreiter, Irene
)
Funktionelle Analyse der HIV-1 Rev Transaktivierung
(Applicant
Hauber, Joachim
)
Funktionelle Analyse des eukaryotischen Initiationsfaktors 5A (elF-5A): Potenzielle Zielstruktur zur Therapie proliferativer Erkrankungen
(Applicants
Bokemeyer, Carsten
;
Hauber, Joachim
)
Identifizierung von Zielproteinen und Untersuchungen zur Spezifität des Ubiqitin-konjugierenden Enzyms UbcM4
(Applicant
Harbers, Klaus
)
Identifizierung zellulärer Rezeptoren für Arenaviren, Hepadnaviren und Hepatitis C-Virus unter Verwendung retroviraler Pseudotyp-Vektoren
(Applicant
Beyer, Winfried
)
Impact of KIR/HLA-C interactions on the anti-HIV activity of NK cells
(Applicant
Körner, Christian
)
Inhibition des eukaryotischen Initiationsfaktors eIF5-A aus Plasmodien und humanen Zellen - Mechanismen der Apoptose-Induktion und Zielstruktur für einen gemeinsamen Therapieansatz zur Behandlung der Malaria und der HIV-Infektion
(Applicants
Hauber, Joachim
;
Holzgrabe, Ulrike
;
Saeftel, Michael
)
Inhibition of Programmed Cell Death by Cytomegalovirus
(Applicant
Brune, Wolfram
)
Mechanismen der Desensibilisierung von G-Protein-gekoppelten Rezeptoren
(Applicant
Lother, Heinz
)
Mechanismus der Entstehung einer Stammzell-Leukämie in MuLV-infizierten Mäusen
(Applicant
Stocking-Harbers, Carol
)
Modulation intrinsischer Immunität durch adenovirale Onkoproteine
(Applicant
Dobner, Thomas
)
Modulation of the NFAT transcription factor by hepatitis B virus and its meaning for viral infection
(Applicant
Bruns, Michael
)
Molecular Mechanisms of the Cytomegalovirus Species Specificity
(Applicant
Brune, Wolfram
)
Molekulare Analyse der CD83 Expression in dendritischen Zellen
(Applicant
Chemnitz, Jan
)
Molekulare Analyse von Konformationsveränderungen viraler Proteine des HIV-1 Kapsids
(Applicant
Wiegers, Klaus-Jochen
)
Molekulare Mechanismen Adenovirus-vermittelter Transformation
(Applicant
Dobner, Thomas
)
Monitoring the emergence and origin of SARS-CoV-2 mutations – Genetic Inter- and Intrahost SARS-CoV-2 diversity in immunocompetent and immunocompromised patients
(Applicants
Aepfelbacher, Martin
;
Fischer, Nicole Brigitte
;
Grundhoff, Adam
)
Photogrammetrische Rekonstruktion der Oberflächenform biologischer Objekte mittels REM-Bilddaten
(Applicant
Hohenberg, Heinz
)
Photogrammetrische Rekonstruktion der Oberflächenform biologischer Objekte mittels REM-Bilddaten
(Applicant
Albertz, Jörg
)
Regulation und Funktion des schadeninduzierten Polymerase alpha-Primase-wtp53 Komplexes im ATM/ATR-vermittelten intra-S-Phasen Kontrollpunkt
(Applicant
Dornreiter, Irene
)
Role of viral microRNAs in Kaposi´s Sarcoma-associated Herpesvirus (KSHV) infection and KSHV-associated Disease
(Applicant
Grundhoff, Adam
)
Spezifische Interaktion von Mutanten p53 mit MAR-DNA Elementen: Molekulare Basis der dominant-onkogenen Wirkung von Mutanten p53?
(Applicant
Deppert, Wolfgang
)
U-box proteins and their function in the ubiquitin/proteasome system: Studies using the nuclear U-box protein UIP5 as an example
(Applicant
Harbers, Klaus
)
Emmy Noether Independent Junior Research Groups
Completed projects
Funktionelle Analyse der Virus-Zell-Interaktion beim Cytomegalovirus mittels hocheffizienter Suchverfahren
(Applicant
Brune, Wolfram
)
Priority Programmes
Completed projects
Kombinierte CpG-Oligodeoxynukleotid/Lipopeptid Liposomen als neuer immunmodulatorischer Impfstoff gegen Hepatitis C Virus Infektion
(Applicant
Will, Hans
)
Modulation of Tumor Angiogenesis by CEACAM1 in a Mouse Model for Mammary Carcinogenesis (WAP-T Mice)
(Applicant
Deppert, Wolfgang
)
Role of importin-alpha isoforms in MERS-Coronavirus interspecies transmission and subsequent infection of the human respiratory tract
(Applicant
Gabriel, Gülsah
)
Collaborative Research Centres
Current projects
SFB 1648: Emerging Viruses: Pathogenesis, Structure, Immunity
(Spokesperson
Addo, Marylyn Martina
)
Completed projects
Apoptose-Inhibitoen des Cytomegalievirus
(Project Head
Brune, Wolfram
)
Apoptose-Inhibitoren des Cytomegalievirus - molekulare Mechanismen und Implikationen für Vektorentwicklung
(Project Head
Brune, Wolfram
)
Apoptose-Inhibitoren des Cytomegalovirus
(Project Head
Brune, Wolfram
)
Einfluß von mutiertem p53 auf die Entstehung und Progression von induzierbaren Mammakarzinomen im Modell der transgenen Maus
(Project Head
Deppert, Wolfgang
)
Kernexportaktivität retroviraler Regulatorproteine
(Project Head
Hauber, Joachim
)
Regulation von Zellzyklus und DNA-Rekombination durch p53
(Project Heads
Deppert, Wolfgang
;
Wiesmüller, Elisabeth Maria
)
SFB 841: Liver Inflammation: Infection, Immune Regulation and Consequences
(Spokesperson
Lohse, Ansgar W.
)
Heisenberg Fellowships
Completed projects
Zellbiologie mit Schwerpunkt Leukämie
(Applicant
Sternsdorf, Thomas Martin
)
Clinical Research Units
Completed projects
Congenital cytomegalovirus infection: identification of factors determining vertical transmission and clinical outcome of infected neonates
(Applicants
Brune, Wolfram
;
Stahl, Ph.D., Felix
)
KFO 296: Feto-maternal immune cross talk: Consequences for maternal and offspring's health
(Spokesperson
Arck, Petra Clara
)
Research Training Groups
Current projects
GRK 2485: Virus detection, pathogenesis and intervention (VIPER)
(Spokesperson
Beineke, Andreas
)
GRK 2771: Humans and Microbes: Reorganisation of Cell Compartments and Molecular Complexes during Infection
(Spokesperson
Aepfelbacher, Martin
)
GRK 2887: VISualization and structure in virus infectION (VISION)
(Spokesperson
Krey, Thomas
)
Completed projects
GRK 805: Protein-Protein Interactions in Signal Transduction
(Spokesperson
Hillen, Wolfgang
)
Subinstitutions
Abteilung Strukturelle Zellbiologie der Viren
Abteilung Virale Zoonosen - One Health
Arbeitsgruppe Emerging Viruses
Nachwuchsgruppe Systembiologie der Arboviren
