Karlsruher Institut für Technologie (KIT)
Institut für Organische Chemie
Address
Fritz-Haber-Weg 6
76131 Karlsruhe
Deutschland
GERiT
This institution in GERiT
76131 Karlsruhe
Projects
Priority Programmes
Current projects
Machine learning of hierarchical ultrafast molecular forcefields (HUMF)
(Applicant
Wenzel, Wolfgang
)
Completed projects
Asymmetric amination reactions with novel chiral ammonium salts
(Applicant
Bräse, Stefan
)
Charge transport through individual perylene-bisimide DNA aggregates using single-walled carbon nanotubes as contact leads
(Applicants
Strunk, Christoph
;
Wagenknecht, Hans-Achim
)
Organo-catalytic asymmetric synthesis of cannabinoids
(Applicant
Bräse, Stefan
)
Organocatalytic Domino Michael-Aldol Reactions for the Construction of Heterocyclic Natural Products
(Applicant
Bräse, Stefan
)
Photophysical and photoelectric properties of phthalocyanine-based MOF thin films
(Applicants
Bräse, Stefan
;
Heine, Thomas
;
Wöll, Christof
)
The role and sources of the 5`deoxyadenosyl radical
(Applicant
Rétey, János
)
Research Grants
Current projects
Enantioselektive Unterscheidung von Cannabis-verwandten flüchtigen organischen Verbindungsgemischen durch Sensorarrays basierend auf nanoporösen chiralen metallorganischen Gerüstfilmen
(Applicants
Bräse, Stefan
;
Heinke, Lars
)
Hemipiperazines – novel peptide-derived thermostable molecular photoswitches
(Applicant
Pianowski, Zbigniev
)
Inkjet Printing of (Semi)conductive MOF Films: From Ink Formulation to Printed Electronic Devices
(Applicant
Begum, Salma
)
Metabolic labeling of RNA by means of synthetic and bioorthogonally reactive nucleoside as fluorogenic probes in living cells
(Applicant
Wagenknecht, Hans-Achim
)
Photoredox catalytic activation of sulfur hexafluoride for the synthesis of pentafluorosulfanylated organic compounds
(Applicant
Wagenknecht, Hans-Achim
)
Postsynthetic construction of molecular chromophore-DNA-architectures as light harvesting systems for photocatalysis
(Applicant
Wagenknecht, Hans-Achim
)
Synthesis of cyclopenta-fused aromatic hydrocarbon radicals
(Applicant
Podlech, Joachim
)
Completed projects
alpha-Acidities of conformationally constrained sulfides, sulfoxides and sulfones
(Applicant
Podlech, Joachim
)
Asymmetric synthesis of oxygen heterocycles with planar-chiral organo-catalysts Synthesis - Catalysis - Theory
(Applicants
Bräse, Stefan
;
Zipse, Hendrik
)
Aus Aminosäure-Bausteinen generierte Ketene als Intermediate in der Organischen Synthese
(Applicant
Podlech, Joachim
)
Chemical photocatalysis with oligonucleotides and short peptides
(Applicant
Wagenknecht, Hans-Achim
)
Controlled synthesis of functionalized oligomers and polymers: Development of methods for the solid supported synthesis of quinoxalin-based oligomers using 1,2-diketosynthons for their investigation and application in materials science.
(Applicants
Bräse, Stefan
;
Jung, Nicole
)
Development of new fluorescent probes for nucleic acids based on aminophthalimide as isosteric base substitution and photostable cyanine-styryl dyes
(Applicant
Wagenknecht, Hans-Achim
)
Development of novel strategies towards the synthesis of N-heterocycles using isocyanide-based multicomponent reactions
(Applicant
Bräse, Stefan
)
Die Totalsynthese der Secalonsäuren
(Applicant
Bräse, Stefan
)
Die Totalsynthese von Epithiodiketopiperazinen
(Applicant
Bräse, Stefan
)
DNA-Systeme für die zeitaufgelöste Beobachtung und zur Modulation des reduktiven Elektronentransfers durch die DNA
(Applicant
Wagenknecht, Hans-Achim
)
Entwicklung von neuen Methoden in der metall-organischen Festphasen-Synthese
(Applicant
Bräse, Stefan
)
Entwicklung von partiellen Orientierungsmedien für die NMR-Spektroskopie
(Applicant
Luy, Burkhard
)
Fast and Robust Two-Dimensional Heteronuclear Correlation Experiments for Small Molecules
(Applicant
Luy, Burkhard
)
Immobilized dithianylium salts and ylidene dithianes for the flexible syntheses of selectively labeled building blocks
(Applicants
Bräse, Stefan
;
Jung, Nicole
)
Layer-by-layer assembled siRNA-nanoparticles as tool to identify strategies for highly efficient siRNA delivery into cells
(Applicants
Breunig, Miriam
;
Wagenknecht, Hans-Achim
)
Messung und Strukturelle Interpretation anisotroper Parameter in der hochauflösenden NMR-Spektroskopie
(Applicant
Luy, Burkhard
)
Metal ion-mediated electron transfer in supramolecular DNA architectures
(Applicant
Wagenknecht, Hans-Achim
)
Nachweis von Punktmutationen mit Hilfe photoelektronischer Wechselwirkungen zwischen zwei fluoreszenten Basensurrogaten
(Applicant
Wagenknecht, Hans-Achim
)
New cyclic peptoids - design and syntheses
(Applicant
Bräse, Stefan
)
NMR Methods for the Unambiguous Identification of meso-Compounds and the Racemate of Their Corresponding Enantiomers
(Applicant
Luy, Burkhard
)
Peptaibols as membrane-active antibiotics: Solid-state 19F-NMR structure-function analysis using tailor-made CF3-labeled amino acids
(Applicant
Ulrich, Anne
)
Photochromic cyclic dipeptides as biocompatible smart materials
(Applicant
Pianowski, Zbigniev
)
Postsynthetic modifications of DNA and RNA by bioorthogonal reactions
(Applicant
Wagenknecht, Hans-Achim
)
Rezeptoraktivierung durch virale Oncoproteine: NMR-Untersuchungen zur Oligomerisierung von Transmembranhelices
(Applicant
Ulrich, Anne
)
Stereoelektronische Effekte in Reaktionen von Sulfoxiden, Sulfiden und Sulfiliminen
(Applicant
Podlech, Joachim
)
Supramolecular DNA-chromophore architectures with optoelectronic function
(Applicants
Colsmann, Alexander
;
Wagenknecht, Hans-Achim
)
Synthese photoreaktiver Sialylglykokonjugate zur Untersuchung der Kohlenhydrat-Kohlenhydrat-Wechselwirkungen von Tumorzellen
(Applicant
Wagenknecht, Hans-Achim
)
Synthesis of helicenes and related compounds
(Applicant
Podlech, Joachim
)
Total syntheses of Parnafungins
(Applicant
Bräse, Stefan
)
Totalsynthese von Perylenchinon-Toxinen
(Applicant
Podlech, Joachim
)
Total synthesis of perylene quinone mycotoxins
(Applicant
Podlech, Joachim
)
Transport across membranes via electrostatic 'charge zippers'
(Applicants
Elstner, Marcus
;
Ulrich, Anne
)
Emmy Noether International Fellowships
Completed projects
Oxidation of DNA-bound peptides and proteins by DNA-mediated electron transfer reactions
(Applicant
Wagenknecht, Hans-Achim
)
Emmy Noether Independent Junior Research Groups
Completed projects
Entwicklung und Anwendung NMR-spektroskopischer Methoden zum Magnetisierungstransfer über große Distanzen und unter Beteiligung stark relaxationsverbreiterter Resonanzen
(Applicant
Luy, Burkhard
)
Research Units
Completed projects
Chemical Spectroscopy photochemical organic reactions in micro reactors
(Applicants
Dittmeyer, Roland
;
Jung, Nicole
;
Zappe, Hans
)
Enhanced measurement of anisotropic NMR parameters using tunable alignment strength and tensor orientation
(Applicant
Luy, Burkhard
)
FOR 2383: Assessing and Controlling Dynamic Local Process Conditions in Microreactors via Novel Integrated Microsensors
(Spokesperson
Stroh, Alexander
)
Heisenberg Professorships
Completed projects
Bioanalytik
(Applicant
Luy, Burkhard
)
Core Facilities
Completed projects
Compounds Platform (ComPlat): Management, storage and sharing of chemical compounds: Installation of an interdisciplinary compound-facility to open available resources of research groups to scientists for a long-term usage and to initiate novel collaborations.
(Applicants
Bräse, Stefan
;
Jung, Nicole
)
In situ nuclear magnetic resonance on processes and products: Pro2NMR
(Applicants
Blümich, Bernhard
;
Luy, Burkhard
;
Nirschl, Hermann
)
Collaborative Research Centres
Current projects
Low energy and fast pulsing spin dynamics
(Project Head
Luy, Burkhard
)
Completed projects
Central Administration
(Project Heads
Barner-Kowollik, Christopher
;
Meier, Michael
)
Enantioselektive Desymmetrisierungsreaktionen durch Kreuzkupplungen
(Project Head
Bräse, Stefan
)
Highly Cross-Linked Polymers for Functional Organic Multi-Layers
(Project Heads
Bräse, Stefan
;
Colsmann, Alexander
)
Kombinatorische Templat-gesteuerte chemische und biomimetische Synthesen sowie Screening von Glycopeptidantibiotika-Bibliotheken
(Project Head
Bräse, Stefan
)
New Approaches Towards Sequence Defined Synthetic Macromolecules
(Project Heads
Barner-Kowollik, Christopher
;
Meier, Michael
)
New Functionalized and Patterned Surface Coatings via Cyclophane-Based Chemical Vapor Deposition (CVD) Polymerization
(Project Heads
Bräse, Stefan
;
Lahann, Joerg
)
NMR Methods for the Characterization of Polymers
(Project Heads
Luy, Burkhard
;
Wilhelm, Manfred
)
Optimized Polymer-Based Alignment Media for NMR Spectroscopy
(Project Heads
Barner, Leonie
;
Luy, Burkhard
)
Preparation of Sequence-Controlled Covalent Networks (COFs) via Cross-Linking of Metal Organic Frameworks
(Project Heads
Bräse, Stefan
;
Wöll, Christof
)
Reversible Single-Chain Folding of Macromolecules via Non-Covalent Interactions
(Project Heads
Barner-Kowollik, Christopher
;
Luy, Burkhard
)
Rezeptoraktivierung durch virale Oncoproteine: NMR-Untersuchungen zur Oligomerisierung von Transmembranhelices
(Project Head
Ulrich, Anne
)
Sequence-Controlled Growth of Cross-Linked Polymer Layers on Surfaces
(Project Heads
Bräse, Stefan
;
Meier, Michael
;
Scheiba, Frieder
)
SFB 1176: Molekulare Strukturierung weicher Materie
(Spokespersons
Barner-Kowollik, Christopher
;
Meier, Michael
)
Tailor-Made Sequence-Controlled Polymer-Dye-Conjugates for Controlling Exciton Dynamics
(Project Heads
Bräse, Stefan
;
Lemmer, Ulrich
;
Meier, Michael
)
DFG Research Centres
Completed projects
Nano-Biology
(Project Head
Ulrich, Anne
)
Heisenberg Fellowships
Completed projects
NMR-Spektroskopie
(Applicant
Luy, Burkhard
)
Major Research Instrumentation
Completed projects
400 MHz NMR-spectrometer with diffusion probe
600 MHz Spektrometer
Confocal microscope for the fluorescent imaging of cells
digitale Austauschkonsole für 500 MHz widebore Festkörper NMR-Spektrometer
HPLC/ESI-Massenspektrometer mit Ionenfalle
Tandem-Massenspektrometer
CRC/Transregios
Completed projects
Heterodinuclear complexes combining electron-rich transition metals and hard Lewis acids and their implementation in cooperative catalysis
(Project Heads
Bräse, Stefan
;
Thiel, Werner R.
)
Luminescent Bi- and Trimetaiiic TADF Metai Complexes with Smart Ligands for OLED Applications
(Project Head
Bräse, Stefan
)
Research data and software
Completed projects
Open Source infrastructure to establish new methods for the acquisition, storage and sharing of information in the field of chemical research: development of a decentralized electronic lab notebook that is connected to a repository for research data
(Applicants
Bräse, Stefan
;
Neumair, Bernhard
;
Scholze, Frank
)
Research Training Groups
Completed projects
GRK 640: Natural Sensory Photoreceptors, Artificial Photoreceptors, Principle of Light Reception and Conversion into a Modulated Signal
(Spokesperson
Dick, Bernhard
)
GRK 768: Biomolecular Switches ? Coding of Proteins via Conformational Changes and Posttranslational Modifications
(Spokesperson
Heinemann, Stefan H.
)
GRK 2039: Molecular architectures for fluorescent cell imaging
(Spokesperson
Wagenknecht, Hans-Achim
)
Clusters of Excellence
Completed projects
EXC 172: DFG-Center for Functional Nanostructures (CFN)
(Spokesperson
Wegener, Martin
)
Graduate Schools
Completed projects
GSC 21: Karlsruhe School of Optics & Photonics (KSOP)
(Spokesperson
Lemmer, Ulrich
)
Clusters of Excellence (ExStra)
Current projects
EXC 2082: 3D Matter Made to Order (3DMM2O)
(Spokespersons
Bunz, Uwe F. H.
;
Selhuber-Unkel, Christine
;
Wegener, Martin
;
Wittbrodt, Joachim
)
NFDI technical and methodological consortia
Current projects
NFDI4Chem – Chemistry Consortium in the NFDI
(Spokesperson
Steinbeck, Christoph
)
