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Institution
Uniklinik Köln
Zentrum für Augenheilkunde
Address
Kerpener Straße 62
50937 Köln
Deutschland
GERiT
This institution in GERiT
50937 Köln
Projects
Research Fellowships
Completed projects
Korneale Lymphangiogenese und korneale Hämangiogenese und ihre Bedeutung für die immunologische Transplantatreaktion nach Hornhauttransplantation
(Applicant
Cursiefen, Claus
)
Vasculo-protective function of circulating myeloid progenitor cells in diabetic retinopathy
(Applicant
Krohne, Tim Ulrich
)
Research Grants
Current projects
Analysis of the impact of donor tissue characteristics on the outcome of Descemet Membrane Endothelial Keratoplasty (DMEK)
(Applicant
Schrittenlocher, Silvia
)
Cologne Clinician Scientist Program
(Applicant
von Stebut-Borschitz, Ruth Esther
)
Donor induced graft tolerance by sCD83 after corneal transplantation
(Applicants
Bock, Felix
;
Steinkasserer, Alexander
)
Functional relevance and molecular mechanisms of tyrosinase in controlling lymphangiogenesis in different ocular diseases
(Applicants
Clahsen, Thomas
;
Cursiefen, Claus
)
The role of ABCB5-expressing mesenchymal stem cells in pterygium pathogenesis
(Applicants
Cursiefen, Claus
;
Notara, Ph.D., Maria
)
Trained immunity in the retina and its influence on retinal degenerative disorders
(Applicant
Langmann, Thomas
)
Completed projects
Analysis of strain-dependent differences in corneal lymphangiogenesis for the identification of new endogenous regulators of lymphangiogenesis
(Applicants
Cursiefen, Claus
;
Reis, André
)
Charakterisierung der Expression, morphologischen Verteilung und Regulation von ATP-binding-cassette Transportern in der Darmmukosa von Patienten mit entzündlichen Darmerkrankungen
(Applicant
Langmann, Thomas
)
Innate immune response in age-related macular degeneration: Inflammasome and microglia activation related to oxidative damage
(Applicants
Krohne, Tim Ulrich
;
Langmann, Thomas
)
Intravitale Mikroskopie zur Charakterisierung der zellulären Dynamik entzündlicher Prozesse an der Augenoberfläche
(Applicant
Steven, Philipp
)
Molekulare Charakterisierung der Mikroglia-Aktivierung bei der Netzhautdegeneration
(Applicant
Langmann, Thomas
)
Tumor-associated lymphangiogenesis and its specific inhibition as a novel therapeutic strategy in malignant melanomas of the conjunctiva
(Applicants
Bosch, Jacobus J.
;
Cursiefen, Claus
;
Heindl, Ludwig M.
)
Untersuchungen zur Funktion des RS1 Proteins - Ein Beitrag zur Aufklärung der molekularen Pathologie der X-gebundenen juvenilen Retinoschisis
(Applicants
Langmann, Thomas
;
Weber, Bernhard H.F.
)
Research Units
Current projects
FOR 2240: (Lymph)Angiogenesis And Cellular Immunity In Inflammatory Diseases Of The Eye
(Spokesperson
Cursiefen, Claus
)
Identification of novel endogenous modulators of developmental and inflammatory lymphangiogenesis by analyzing mouse strain-specific differences
(Applicants
Clahsen, Thomas
;
Reis, André
)
The role of ABCB5-expressing limbal epithelial stem cells in corneal lymphangiogenic privilege and pterygium pathogenesis
(Applicant
Notara, Ph.D., Maria
)
Completed projects
Central Project 1 (Cologne Experimental Eye Imaging Center (CEE-IC))
(Applicant
Steven, Philipp
)
Cologne Experimental Eye Imaging Center (CEE-IC)
(Applicant
Bock, Felix
)
Coordination Funds
(Applicant
Cursiefen, Claus
)
Funktionelle Analyse des FAM161A Proteins und Aufklärung der FAM161A-assoziierten Netzhautdegeneration
(Applicants
Langmann, Thomas
;
Stöhr, Heidi
)
Identification of novel endogenous modulators of (inflammatory) lymphangiogenesis by analyzing mouse strain-specific differences
(Applicants
Cursiefen, Claus
;
Reis, André
)
Induction of corneal transplant tolerance by anti(lymph)angiogenic therapy
(Applicants
Bock, Felix
;
Cursiefen, Claus
)
Lymph- and hemangiogenesis in ocular graft-versus-host disease
(Applicant
Steven, Philipp
)
Mikroglia bei Netzhautdegeneration
(Applicant
Langmann, Thomas
)
Myeloid cell function in corneal hem- and lymphangiogenesis
(Applicants
Eming, Sabine
;
Hos, Deniz
)
Role of complement receptors and microglia in age-related macular degeneration
(Applicant
Langmann, Thomas
)
The role of midkine in tumor-associated lymphangiogenesis and metastasis of ocular malignant melanoma.
(Applicants
Bosch, Jacobus J.
;
Heindl, Ludwig M.
)
Collaborative Research Centres
Current projects
Administration
(Project Head
Cursiefen, Claus
)
Galectins in the pathogenesis of retinal neovascular and inflammatory diseases
(Project Heads
Langmann, Thomas
;
Rüger, Maria Adele
)
Imaging Core Unit (ICU)
(Project Head
Bock, Felix
)
In depth investigation of the molecular signaling mechanisms and cellular function of midkine, neuropilin-2 and sFLT1 in conjunctival and uveal melanoma
(Project Heads
Bosch, Jacobus J.
;
Heindl, Ludwig M.
)
Integrated Research Training Group “Eye and Inflammation” (EI)
(Project Heads
Bock, Felix
;
Prokosch-Willing, Verena
)
Mitochondrial DNA at the interface between mitochondrial dysfunction and neuroinflammation in glaucoma
(Project Heads
Liu, Hanhan
;
Trifunovic, Aleksandra
)
NLRP3 inflammasome as a therapeutic target in atrophic age-related macular degeneration
(Project Head
Krohne, Tim Ulrich
)
Personalized anti(lymph)angiogenic therapy and immunomodulation in high-risk corneal transplantation
(Project Heads
Bock, Felix
;
Cursiefen, Claus
)
Role of macrophage-dependent osmoprotective and hypoxic signal transduction in inflammatory corneal diseases
(Project Heads
Hos, Deniz
;
Jantsch, Jonathan
)
SFB 1607: Towards immunomodulatory and anti(lymph)angiogenic therapies for age-related blinding eye diseases
(Spokesperson
Cursiefen, Claus
)
Site-specific chronic inflammation and fibrosis in Fuchs endothelial corneal dystrophy
(Project Heads
Bachmann, Björn
;
Matthaei, Mario Magnus Goswin
;
Odenthal, Margarete
)
Strain- and metabolism-dependent genetic variations of (lymph)angiogenesis: identification of candidates and influence on corneal wound healing
(Project Heads
Clahsen, Thomas
;
Reis, André
)
The role of limbal stem cells in corneal (lymph)angiogenesis, inflammation and UV-induced pterygium pathogenesis
(Project Heads
Notara, Ph.D., Maria
;
Schumacher, Björn
)
Thrombospondin-1 and NF-κB signaling in ocular graft-versus-host disease (GVHD)
(Project Heads
Pasparakis, Manolis
;
Steven, Philipp
)
Completed projects
Charakterisierung der Expression, morphologischen Verteilung und Regulation von ATP-Binding-Cassette Transportern in der Darmmukosa von Patienten mit entzündlichen Darmerkrankungen
(Project Heads
Langmann, Thomas
;
Schmitz, Gerd
)
DNA/RNA Analytik und Arraytechnologie
(Project Heads
Langmann, Thomas
;
Schmitz, Gerd
)
Modulation of dendritic cell entry into afferent lymphatics to prevent graft rejection after (corneal) transplantation
(Project Head
Cursiefen, Claus
)
Priority Programmes
Current projects
Desialylation as trigger of microglia responses in the aging and degenerating retina
(Applicants
Langmann, Thomas
;
Neumann, Harald
)
Mesostructured composite chitosan membranes for the reconstruction of Corneal Tissue
(Applicants
Lang, Gregor
;
Zwingelberg, Sarah
)
Clinical Trials
Completed projects
Prophylactic Intraoperative Adjuvant Therapy with 5-Fluorouracil and Low Molecular Weight Heparin for the Prevention of Proliferative Vitreoretinopathy (PVR) in High-risk Patients with Primary Rhegmatogenous Retinal Detachment.
(Applicant
Schaub, Friederike
)
Additional Information
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