Project Details

Professor Dr. Thomas Benzing

Address Uniklinik Köln
Klinik II für Innere Medizin
Nephrologie, Rheumatologie, Diabetologie und Allgemeine Innere Medizin
Kerpener Straße 62
50937 Köln

Projects

As Applicant
- Current projects
  - Alterations of slit diaphragm proteins and the pathogenesis of albuminuria and FSGS (Clinical Research Units)
  - Mechanical stress protection at the kidney filtration barrier (Research Units)
  - Coordination Funds (Clinical Research Units)
  - Metabolic deregulation, genome instability, and the progression of chronic kidney disease (Research Units)
  - The role of altered proteolytic protein processing and protein structural changes in podocyte dysfunction, effacement, and albuminuric kidney disease (Research Grants)
- Completed projects
As Leader
- Completed projects
  - Konfokales Laserscanning-Mikroskop für Multifluoreszenz-Detektion (Major Research Instrumentation)
As Spokesperson
- Current projects
  - EXC 2030: CECAD - Excellent in Aging Research (Clusters of Excellence (ExStra))
  - KFO 329: Disease pathways in podocyte injury – from molecular mechanisms to individualized treatment options (Clinical Research Units)
As Participating Researcher
- Completed projects
  - EXC 229: Cellular Stress Responses in Aging-Associated Diseases (Clusters of Excellence)
  - GRK 2407: Inflammatory and cellular stress signaling: Switches to vascular dysfunction (Research Training Groups)
As Project Head
- Current projects
  - Regulated cell death and kidney fibrosis as a consequence of mutation of cilia-associated genes (Collaborative Research Centres)
- Completed projects
  - Stomatins are palmitoylated and attached to plasma membrane cholesterol to couple associated ion channels into mechanosensitive multi-protein complexes (Collaborative Research Centres)
  - The role of neph proteins in cell type specification, junction remodelling and the organization of epithelial cell arrays (Collaborative Research Centres)
  - Posttranslational control of MEC-2/Podocin-associated mechanosensitive ion channel complexes (Collaborative Research Centres)
  - Phosphorylation-dependent regulation of AATF controls p53-dependent apoptosis in the UV-induced DNA damage response of the skin (Collaborative Research Centres)
  - The role of cilia-associated proteins in signaling from the tumor microenvironment (Collaborative Research Centres)
As Participating Person
- Completed projects
  - Molekulare Pathogenese der Zystennieren bei Von-Hippel-Lindau-Syndrom (Research Grants)
  - The VHL/HIF-axis in the regulation of cellular stress resistance (Research Grants)
As Co-Investigator
- Current projects
  - Cologne Clinician Scientist Program (Research Grants)

Servicenavigation

Hauptnavigation

Professor Dr. Thomas Benzing

Additional Information

Servicenavigation

Hauptnavigation

Professor Dr. Thomas Benzing

Additional Information

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