Universitäts-Herzzentrum Freiburg-Bad Krozingen
Klinik für Kardiologie und Angiologie
Address
Hugstetter Straße 55
79106 Freiburg
Deutschland
GERiT
This institution in GERiT
79106 Freiburg
Projects
Research Fellowships
Completed projects
Are Endothelial Cell and Granulocyte Protein Arginine Deiminase 4 on the Pathway of Inflammasome-Activation, Advancing Myocardial Ischemia Reperfusion Injury?
(Applicant
Heger, Lukas
)
Entwicklung bispezifischer Einzelketten-Antikörper (scFv) zur Anreicherung endothelialer Progenitorzellen (EPC) am atherosklerotischen Gefäßendothel.
(Applicant
Ahrens, Ingo
)
Generierung neuer Bindungsproteine gegen aktivierte, leukozytäre und thrombozytäre Integrine als anti-thrombotisches bzw. anti-inflammatorisches Pharmakon, sowie Detektion neuer leukozytärer Aktivierungsmarker und Oberflächenmarker instabiler, atherosklerotischer Plaques.
(Applicant
Diehl, Ph.D., Philipp
)
Identifikation und Charakterisierung endothelspezifischer Transkriptionsfaktoren anhand des Regulationsmechanismus von KDR/flk-1
(Applicant
Moser, Martin
)
Impact of statins and Canakinumab on the heart and immune system – An evaluation with molecular imaging
(Applicant
Maier, Alexander
)
Molecular PET-MRI of Factor XIII activity for the detection of intravascular thrombosis and differentiation of its role in myocardial wound healing
(Applicant
Heidt, Timo Sebastian
)
Pathogen-specific imaging of endocarditis
(Applicant
Krohn-Grimberghe, Marvin
)
Quantitative and qualitative contribution of splenic monocytes to plaque development
(Applicant
Hilgendorf, Ingo
)
The design and conduct of clinical trials for antithrombotic regimes in cardiac patients
(Applicant
Olivier, Christoph
)
The role of T cell response to antigenic ApoB-100 peptides in vaccination strategies against atherosclerosis
(Applicant
Wolf, Dennis
)
Research Grants
Current projects
Bio-inspired multifunctional block copolymers for the dissolution of risky atherosclerotic plaques
(Applicants
Cölfen, Helmut
;
Hilgendorf, Ingo
)
Extracellular ASC Specks as functional inflammasome in cardiovascular disease
(Applicant
Merz, Julian
)
Mechanisms by which clonal haematopoiesis of indeterminate potential (CHIP)-driver mutations confer cardiovascular risk
(Applicant
Hilgendorf, Ingo
)
MicroRNA-100 - a protectice epigenetic player in ischemia-reperfusion injury
(Applicant
Pankratz, Franziska
)
Role of G protein-coupled receptor 15 (GPR15) in T cell recruitment and function during viral myocarditis
(Applicant
Lindner, Diana
)
Temporal dynamics of monocyte migration after myocardial infarction with 19F-MRI
(Applicants
Bock, Michael
;
Maier, Alexander
)
The impact of macrophage-derived cardiac injury response gene HexB (hexosaminidase B) on cardiac remodelling
(Applicant
Hilgendorf, Ingo
)
Completed projects
Activated platelets in emergency hematopoiesis after myocardial infarction
(Applicant
Heidt, Timo Sebastian
)
Analyse der myokardialen Synchronizität des linken und rechten Herzens mit MR Phasenkontrastbildgebung
(Applicant
Föll, Daniela
)
Biofunctional Assessment and Interventional Treatment of Coronary Inflammation guided by Magnetic Resonance Imaging
(Applicants
Bock, Michael
;
Heidt, Timo Sebastian
;
von zur Mühlen, Constantin
)
Characterization of HoxBS, a key regulator in blood vessel formation
(Applicant
Moser, Martin
)
Characterization of the electrophysiological substrate in patients with atrial fibrillation - Role of the restitution of atrial conduction velocity and of the voltage for the development of atrial fibrillation
(Applicants
Dössel, Olaf
;
Jadidi, Amir
;
Kohl, Peter
;
Schmitt, Claus
)
Charakterisierung von BMPER in der Blutgefässentwicklung und bei vaskuären Erkrankungen
(Applicant
Moser, Martin
)
Der Einfluss von Dabigatran und Rivaroxaban auf die Thrombozytenfunktion- Evaluation einer zukünftigen Kombination von oralen direkten Antikoagulantien mit Thrombozytenaggregationshemmern
(Applicant
Olivier, Christoph
)
Endothelial regulators of heart failure
(Applicants
Helbing, Thomas
;
Moser, Martin
)
Entwicklung von MR-Phasenkontrast-Bildgebung und Auswertemethoden zur Untersuchung von Herzmuskelfaserstrukturen
(Applicant
Hennig, Jürgen
)
Entwicklung von Parametern zur Beurteilung der chirurgischen Ventrikelrekonstruktion mittels Magnetresonanztomographie und Echokardiographie
(Applicant
Doenst, Torsten
)
Extracellular ATP and purinergic receptors in atherosclerosis
(Applicants
Stachon, Peter
;
Zirlik, Andreas
)
Measurement of heart hall morton with fast phase contrast MRI techniques: Methology and clinical applications
(Applicant
Hennig, Jürgen
)
MicroRNA-194 as a modulator of vascular inflammation
(Applicant
Grundmann, Sebastian
)
MicroRNA-Regulation des adaptiven Blutgefäßwachstums
(Applicant
Grundmann, Sebastian
)
Molekulare Ultraschallbildgebung aktivierter Thrombozyten auf hämokompatiblen Oberflächen
(Applicant
von zur Mühlen, Constantin
)
MR Phasenkontrastbildgebung zur kardialen Ischämiediagnostik und quantitativen Analyse der Kontraktilität bei linksventrikulärer Dilatation
(Applicant
Föll, Daniela
)
Noninvasive multitarget-imaging of vascular inflammation and its progression in atherosclerosis using MRI
(Applicants
von Elverfeldt, Dominik
;
von zur Mühlen, Constantin
)
Transcriptional control of endothelial tip cell function by Neuronal helix-loop-helix PAS (Per-ARNT-Sim) 4 -NPAS4-
(Applicant
Moser, Martin
)
Vascular in vivo MRI for the detection of arterial thrombosis by targeting activated platelets - new imaging agents for MRI approaches
(Applicant
von zur Mühlen, Constantin
)
Heisenberg Grants
Current projects
Innate immune cell engagement in cardiovascular disease
(Applicant
Hilgendorf, Ingo
)
Collaborative Research Centres
Current projects
Impact of Heterogeneous Macrophage Origins on Ischaemic and Non-Ischaemic Cardiac Lesions
(Project Head
Hilgendorf, Ingo
)
Phenotypes, Interactions, and Functions of Cells of the Adaptive Immune System in the Healing Heart
(Project Head
Wolf, Dennis
)
Steering Atrial Lesion Electro-Physiology by Cell Type-Specific Targeting
(Project Heads
Kohl, Peter
;
Westermann, Dirk
)
Completed projects
Cross-Talk Between the Heart and the Haematopoietic Niche in Post-Myocardial Infarction Lesion Remodelling
(Project Heads
Cabezas-Wallscheid, Nina
;
Heidt, Timo Sebastian
)
Interventional Treatment and Molecular Imaging of Coronary and Myocardial Inflammation by Magnetic Resonance Imaging
(Project Heads
Bock, Michael
;
Heidt, Timo Sebastian
;
von zur Mühlen, Constantin
)
WBP Fellowship
Current projects
The design and conduct of clinical trials for the use of anticoagulation and antiplatelet regimes in patients with atrial fibrillation
(Applicant
Gjermeni, Diona
)
CRC/Transregios
Completed projects
Characterization of BMPER, an endothelial precursor cell derived BMP regulator in vascular differentiation and remodeling
(Project Head
Moser, Martin
)
Molecular Mechanisms of Matrix Remodeling in Inflammatory Cardiomyopathy
(Project Heads
Schultheiss, Heinz-Peter
;
Westermann, Dirk
)
Myeloid cells in the development of choroidal neovascularisation in the eye
(Project Heads
Hilgendorf, Ingo
;
Lange, Ph.D., Clemens A.K.
)
Emmy Noether Independent Junior Research Groups
Completed projects
Macrophage proliferation, the engine of plaque progression
(Applicant
Hilgendorf, Ingo
)