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Julius-Maximilians-Universität Würzburg
Biozentrum der Universität Würzburg
Lehrstuhl für Biochemie I

Address Am Hubland
97074 Würzburg
Deutschland

GERiT This institution in GERiT

97074 Würzburg

Projects

Priority Programmes
- Completed projects
  - Characterization of factors and mechanisms of starvation-induced control of TOP mRNA translation
    (Applicants Fischer, Utz ; Vogel, Jörg )
  - Coordination project
    (Applicant Fischer, Utz )
  - Mechanistic and functional characterization of Makorin 1 mRNPs
    (Applicants König, Ph.D., Julian ; Roignant, Jean-Yves ; Zarnack, Katharina )
  - Mobility of murine replication proteins in the nucleus
    (Applicant Grummt, Friedrich )
  - mRNP assembly at the 3' splice site studied by functional genomics and structural biology
    (Applicants König, Ph.D., Julian ; Sattler, Michael )
  - The control of the initiation step of DNA replication by proteinkinase Dbf4/Cdc7 Regulation des murinen "origin recognition complex (ORC)" durch Cyclin-Cdk-Komplexe
    (Applicant Grummt, Friedrich )
  - The role of the miR-26 family in neurogenesis
    (Applicants Becker, Matthias ; Fischer, Utz )
Emmy Noether Independent Junior Research Groups
- Completed projects
  - Aufbau, Struktur und Funktion von Ubiquitin Ligase Komplexen der humanen CBC Familie und homologer Komplexe der Hefe Saccharomyces cerevisiae
    (Applicant Buchberger, Alexander )
Research Grants
- Current projects
- Completed projects
Research Units
- Completed projects
  - Biosynthesis of the translation machinery: identification of regulatory factors and mechanisms
    (Applicant Fischer, Utz )
  - Combination of transcriptome-wide and structural approaches to study SHE binding to RNA localization elements in budding yeast
    (Applicants König, Ph.D., Julian ; Niessing, Dierk ; Zarnack, Katharina )
  - FOR 855: Cytoplasmic Regulation of Gene Expression
    (Spokespersons Fischer, Utz ; Wahle, Elmar )
  - FOR 2333: Macromolecular Complexes in mRNA translocation
    (Spokesperson Niessing, Dierk )
  - Molecular dissection of the assembly pathway of spliceosomal U snRNPs
    (Applicant Fischer, Utz )
  - Zentralprojekt
    (Applicant Fischer, Utz )
Heisenberg Fellowships
- Completed projects
  - Neurobiologie
    (Applicant Scholz, Henrike )
  - Zellbiologie
    (Applicant Buchberger, Alexander )
Heisenberg Professorships
- Completed projects
  - Zellbiologie
    (Applicant Gallant, Peter )
Heisenberg Grants
- Current projects
  - Cracking the Molecular Code of Splicing and RNA Modifications
    (Applicant König, Ph.D., Julian )
Collaborative Research Centres
- Current projects
  - A Supramolecular Chemical Biology Approach to Studying Protein–RNA-Based Regulatory Switches
    (Project Heads Besenius, Pol ; König, Ph.D., Julian ; Schmid, Friederike )
  - Targeting MYCN-dependent resolution of transcription-replication conflicts
    (Project Heads Büchel, Gabriele ; Henssen, Anton )
- Completed projects
DIP Programme
- Current projects
  - Quantitative and mechanistic dissection of messenger RNA stability
    (Applicants Fischer, Utz ; Ulitsky, Ph.D., Igor )
CRC/Transregios
- Current projects
  - Analyzing and targeting non-catalytic functions of Aurora-A in AML
    (Project Heads Büchel, Gabriele ; Wolf, Elmar )
  - Integrated Research Training Group
    (Project Heads Bremm, Anja ; Büchel, Gabriele )
  - The mechanistic and functional impact of RNA modifications on alternative splicing
    (Project Heads Dieterich, Christoph ; König, Ph.D., Julian ; Roignant, Jean-Yves )
- Completed projects
  - Gene expression profiling and functional genomics
    (Project Heads Ade, Carsten Patrick ; Wanzel, Michael )
  - The analysis of staphylococcal infections by means of new imaging techniques
    (Project Heads Hacker, Jörg Hinrich ; Szalay, Aladar )
Core Facilities
- Current projects
  - Platform for Image-processing of cryo-EM image data
Research Training Groups
- Current projects
  - GRK 2243: Understanding Ubiquitylation: From Molecular Mechanisms To Disease
    (Spokesperson Buchberger, Alexander )
  - GRK 2859: R-loop Regulation in Robustness and Resilience
    (Spokesperson Luke, Ph.D., Brian )
- Completed projects
  - GRK 520: Immunomodulation
    (Spokesperson Hünig, Thomas )
  - GRK 690: Charge Density: Theory and Experiment
    (Spokesperson Engels, Bernd )
  - GRK 1048: Molecular Basis of Organ Development in Vertebrates
    (Spokesperson Schartl, Ph.D., Manfred )
International Research Training Groups
- Completed projects
  - GRK 1141: Signal transduction: where cancer and infection converge
    (Spokesperson Rapp, Ulf Rüdiger )
Graduate Schools
- Completed projects
  - GSC 106: Graduate School for Life Sciences (GSLS)
    (Spokesperson Kisker, Caroline )

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