Albert-Ludwigs-Universität Freiburg
Institut für Organische Chemie
Address
Albertstraße 21
79104 Freiburg
Deutschland
GERiT
This institution in GERiT
79104 Freiburg
Projects
Research Grants
Current projects
Atom economic Rhodium catalyzed cyclization of allenyl-/alkynyl indoles and tryptamines as key step for the synthesis of biologically active tetrahyrocarbazoles, tetrahydro-β-carbolines and tetrahydropyrido[1,2]indoles
(Applicant
Breit, Bernhard
)
Combination of transition metal-catalyzed (hydro)formylation and organocatalysis for the tandem synthesis of diindolylmethanes, porphyrins and BODIPY fluorescent dyes
(Applicant
Breit, Bernhard
)
Development of novel asymmetric allylation reactions by dual photoredox-/transition metal catalysis
(Applicant
Breit, Bernhard
)
Exploiting Chalcogen-Containing Compounds in Donor-Acceptor Cyclopropane and Cyclobutane Chemistry: Access to Four- to Nine-Membered Heterocycles
(Applicant
Werz, Daniel B.
)
Inorganic polyphosphate in eukaryotes - synthesis, detection, metabolism and physiology
(Applicant
Jessen, Henning
)
The BODIPY scaffold as a core chromophore for extended, oligomeric, and helically chiral π-systems
(Applicant
Werz, Daniel B.
)
Completed projects
Ammonium Sensor Proteins in Signal Transduction
(Applicant
Andrade, Susana
)
anti-Carbopalladations of C-C Triple Bonds: Mechanistic Investigations and Starting Point for Novel Domino Reactions
(Applicant
Werz, Daniel B.
)
Atom economic rhodium-catalyzed synthesis of lactones as key step for the construction of natural macrolactones
(Applicant
Breit, Bernhard
)
Desymmetrization of Prochiral Sulfoxides: A Novel Asymmetric Synthesis of Sulfoxides
(Applicant
Brückner, Reinhard
)
Dirigierte asymmetrische Hydroformylierung mittels reversibel gebundener Katalysator-dirigierender Gruppen
(Applicant
Breit, Bernhard
)
Efficient Syntheses of Natural and Unnatural Benzotropolones and Pulvinones. Total Synthesis of the Fungal Dye Aurantricholone
(Applicant
Brückner, Reinhard
)
Green Chemistry for Catalytic C-C Coupling of Renewable Feedstocks
(Applicant
Breit, Bernhard
)
Hybrid Molecules From Benzylguanidine and Cytotoxic Drugs (Busulfan, Melphalan, Thiotepa) for Specific Therapy of Neuroblastoma
(Applicants
Brückner, Reinhard
;
Handgretinger, Ph.D., Rupert
)
In-plane ( ) 2-,3-,5-,6-(10,-11-?)-Elektronendelokalisierung zwischen vier N-, vier NO- und vier C-Zentren - Festkörperstrukturen - Elektronendichteverteilung
(Applicant
Prinzbach, Horst
)
Kombinierter enzymatischer und metallorganischer Zugang zu Naturstoffen mit Deoxypropionat-Einheiten
(Applicant
Breit, Bernhard
)
Reagens-dirigierende Gruppen als Steuerungsinstrumente für Selektivität in Gerüst-aufbauenden Reaktionen
(Applicant
Breit, Bernhard
)
Redoxneutral Propargylic CH-Activation: from Mechanistic Investigations towards better Catalysts
(Applicants
Breit, Bernhard
;
Heller, Detlef
)
Selbstorganisation zweizähniger Liganden für die kombinatorische homogene Katalyse mittels Wasserstoffbrückenbindungen
(Applicant
Breit, Bernhard
)
Supramolecular Axial Chiral Ligands for Asymmetric Catalysis
(Applicant
Breit, Bernhard
)
Synthesis and Cellular Delivery of myo-Inositol Pyrophosphate Prometabolites; the InsP8 Challenge
(Applicant
Jessen, Henning
)
Totalsynthese natürlicher und unnatürlicher Carotinoid-Butenolide: Peridinin, Pyrrhoxanthin und Modellchromophore des Lichtsammel-Chromoproteins aus Amphidinium carterae
(Applicant
Brückner, Reinhard
)
Total Synthesis - Partly Including the 3D-Assignments of Hitherto Unknown Stereocenters - of 3-(Polyenoyl)tetramic Acid and 3 (Polyenoyl)hydroxypyridone Natural Products: Militarinones, Farinosone B, Fumosorinone, and two Anomeric Aurantosides
(Applicant
Brückner, Reinhard
)
Transport of Nitrate and Nitrite across Cell Membranes
(Applicants
Andrade, Susana
;
Einsle, Oliver
)
Vierfach gebundener Sauerstoff in einem Kohlenwasserstoff-Käfig
(Applicant
Werz, Daniel B.
)
Emmy Noether Independent Junior Research Groups
Completed projects
Transport of Ammonium across Prokaryotic and Eukaryotic Membranes
(Applicant
Andrade, Susana
)
Ungelöste mechanistische und synthetische Probleme beim Aufbau von O- und C-Glykosiden - Untersuchungen in Lösung und an der festen Phase
(Applicant
Werz, Daniel B.
)
Heisenberg Fellowships
Completed projects
From donor-acceptor-substituted cyclopropanes via domino reactions to carbohydrate and carbohydrate mimetics
(Applicant
Werz, Daniel B.
)
Collaborative Research Centres
Completed projects
Aufbau von Proteinnetzwerken mit Membrankomponenten
(Project Head
Schulz, Georg E.
)
Charakterisierung von Molmassen, Funktionalitäten und thermischen Eigenschaften von Makromolekülen und Telechelen
(Project Heads
Frey, Holger
;
Schulz, Georg E.
)
Design und Synthese neuartiger Prodrugs der cytotoxischen Antibiotika CC-1065 und Duocarmycin für deine selektive Krebstherapie
(Project Head
Brückner, Reinhard
)
Epigenetische Wirkstoffentwicklung: Molekül Identifizierung und Optimierung, sowie Target Validierung
(Project Heads
Breit, Bernhard
;
Einsle, Oliver
;
Günther, Stefan
)
Kristallstrukturanalysen zum Verständnis von Protein-Wechselwirkungen
(Project Head
Schulz, Georg E.
)
Kristallstrukturenanalysen zum Verständnis von Protein-Wechselwirkungen
(Project Head
Schulz, Georg E.
)
Stereoselektive Synthese von Butenolid-Naturstoffen
(Project Head
Brückner, Reinhard
)
Tailor-made glycosphingolipids as a toolkit to visualize domain formation and lipid-protein interactions
(Project Heads
Steinem, Claudia
;
Werz, Daniel B.
)
Research Fellowships
Completed projects
Synthese und Derivatisierung von Farinosen A für Untersuchungen zur Neuroregeneration
(Applicant
Jessen, Henning
)
Totalsynthese des Proteinkinace-C-Inhibitors(+)-Staurosporin
(Applicant
Berkenbusch, Thilo
)
Emmy Noether International Fellowships
Completed projects
Automatische Festphasensynthese des Tumor-Antigens Globo-H
(Applicant
Werz, Daniel B.
)
Major Research Instrumentation
Completed projects
300 MHz NMR-Spektrometer
400 MHz supraleitendes FT-NMR Spektrometer mit Kryoprobenkopf
700 MHz NMR Spectrometer
Austauschkonsole für 500 MHz NMR-Spektrometer
Hochauflösendes LC/GC-Massenspektrometer
Parallelautoklavenstation zum Katalysator-Screening
Priority Programmes
Current projects
Nitrogen-rich redox-active monomers for COF battery materials (NITROCOF)
(Applicants
Dumele, Oliver
;
Esser, Birgit
)
WBP Fellowship
Current projects
New methodology for the synthesis of tetrasubstituted alkenes
(Applicant
Xie, Ph.D., Hui
)
International Research Training Groups
Completed projects
GRK 1038: Catalysts and Catalytic Reactions for Organic Synthesis
(Spokesperson
Breit, Bernhard
)
Research Training Groups
Current projects
GRK 2202: Transport across and into membranes
(Spokesperson
Friedrich, Thorsten
)
Completed projects
GRK 434: Biochemistry of Enzymes
(Spokesperson
Fuchs, Georg
)
GRK 1976: Functional Diversity of Cofactors in Enzymes
(Spokesperson
Bechthold, Andreas
)
Clusters of Excellence (ExStra)
Current projects
EXC 2189: CIBSS - Centre for Integrative Biological Signalling Studies
(Spokespersons
Driever, Wolfgang
;
Hunte, Carola
;
Kleine-Vehn, Jürgen
;
Weber, Wilfried
)
EXC 2193: Living, Adaptive and Energy-autonomous Materials Systems (livMatS)
(Spokespersons
Fischer, Anna
;
Rühe, Jürgen
;
Speck, Thomas
)
