Network-level mechanisms underlying adaptation of motor control (B06*)

• Subject Area: Cognitive, Systems and Behavioural Neurobiology
• Term: since 2025
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 431549029

Project B06 aims to characterize the neural mechanisms underlying error- and reward-based motor adaptation learning of human reaching movements. We use task-based functional brain imaging (fMRI) and effective connectivity analyses to disentangle how cortical-basal ganglia-cerebellar loops interact in order to enable motor adaptation in the presence and absence of monetary reward feedback. The inclusion of volunteers across the lifespan and the longitudinal assessment of stroke patients from the acute to the chronic stage allow us to address how these network dynamics are affected by aging and elevated levels of motor network plasticity early after stroke.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1451: Key mechanisms of motor control in health and disease
• Applicant Institution: Universität zu Köln
• Project Heads: Professor Dr. Gereon Rudolf Fink; Dr. Lukas Jan Volz