Circuit mechanisms interfacing adaptive motivation and motor control — Depression as a model of reversible motor control impairment (C06)

• Subject Area: Cognitive, Systems and Behavioural Neurobiology ; Biological Psychiatry
• Term: since 2021
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 431549029

Project C06 investigates the neural mechanisms by which motivation is translated into motor actions within the conceptual framework of adaptive motor control. Depression serves here as a model of reversible motor control impairment. Specifically, project C06 aims to dissect the various components of motivated motor behavior - including programming, execution, and adaptation - and to explore their modulation by physiological states, encompassing metabolic signals and inflammation.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1451: Key mechanisms of motor control in health and disease
• Applicant Institution: Universität zu Köln
• Project Heads: Professor Dr. Frank Jessen; Professor Dr. Marc Tittgemeyer