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Professor Dr. Hartmut Geiger

Address Universität Ulm
Institut für Molekulare Medizin
Albert-Einstein-Allee 11
89081 Ulm

Projects

As Applicant
- Current projects
  - Regulation of the histone 4 epigenetic landscape upon hematopoietic stem cell aging (Research Units)
  - Age-related clonal hematopoiesis and its link to age-related changes in the bone marrow microenvironment (Research Grants)
  - Aging, hematopoietic stem cells, gene expression and clonality, cell by cell (Research Grants)
- Completed projects
  - Changes in the interaction of aged hematopoietic stem cells with the bone marrow niche/stroma: implications for stem cell aging (Clinical Research Units)
  - Alterations of H3K9me2 in hematopoietic stem cells: implications for aging and myeloid leukemogenesis (Research Units)
  - Restoring the functionality of the old immune system by rejuvenation of aged hematopoietic stem cells (Research Grants)
As Leader
- Completed projects
  - KFO 142: Molecular and Cellular Aging - From Mechanisms to Clinical Perspectives (Clinical Research Units)
  - Tisch-Durchflusszytometer (Major Research Instrumentation)
  - Automatic slide scanning microscope for brightfield and fluorescence microscopy (Major Research Instrumentation)
As Spokesperson
- Current projects
  - SFB 1506: Aging at Interfaces (Collaborative Research Centres)
- Completed projects
  - GRK 1789: Cellular and Molecular Mechanisms in Aging (CEMMA) (Research Training Groups)
As Participating Researcher
- Completed projects
  - GRK 2254: Heterogeneity and evolution in solid tumors (HEIST): Molecular characterization and therapeutic consequences (Research Training Groups)
  - GSC 270: International Graduate School in Molecular Medicine Ulm (Graduate Schools)
As Project Head
- Current projects
  - Mechanisms of aging and rejuvenation of human hematopoietic stem cells (Collaborative Research Centres)
  - Computational Modeling of Hematopoietic Stem Cell Aging (Collaborative Research Centres)
  - Administrative Core: Central Tasks of the CRC (Collaborative Research Centres)
  - Tissues and animals for aging research – an interdisciplinary approach (Collaborative Research Centres)
- Completed projects
  - Die Rolle des Retinoblastom-Tumorsuppressor-Gens in der Zelldifferenzierung im hämatopoetischen System (Collaborative Research Centres)
  - The role of stem cell circulation in trauma (Collaborative Research Centres)
  - Bioactive peptides in normal and compromised hematopoiesis (Collaborative Research Centres)
  - The contribution of mechanisms of aging of HSCs to leukemia initiation and progression (Collaborative Research Centres)
  - Notch signaling as a novel target of AML/ETO (Collaborative Research Centres)
As Participating Person
- Completed projects
  - Investigation of the role of the nuclear receptor NR4a1 during bone turnover and maintenance of the hematopoietic niche in the bone marrow (Priority Programmes)

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