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Professor Dr. Jochen Hühn

Address Helmholtz-Zentrum für Infektionsforschung (HZI)
Inhoffenstraße 7
38124 Braunschweig

Projects

As Applicant
- Completed projects
  - Negative Feedback-Regulation durch das Zytokin IFN-gamma (Research Grants)
  - Stabilität und Plastizität von T-Zellen und Mikroglia bei akuten entzündlichen ZNS-Prozessen (Research Grants)
  - Untersuchung der Rolle von regulatorischen T-Zellen in der Pathogenese von Virus-induzierten Erkrankungen des zentralen Nervensystems (Research Units)
  - Epigenetische Marker zur Quantifizierung von inflammatorischen und regulatorischen T-Zellen in Autoimmunpatienten (Clinical Research Units)
  - Neonatal imprinting of tolerogenic properties in stromal cells from gut-draining lymph nodes by commensal microbiota (Priority Programmes)
As Participating Researcher
- Current projects
  - EXC 2155: RESIST - Resolving Infection Susceptibility (Clusters of Excellence (ExStra))
As Project Head
- Current projects
  - Long-lasting consequences of early-life influenza A virus infection for the tissue-resident memory T cell niche and susceptibility to secondary infections (CRC/Transregios)
  - Dynamics, epigenetic signatures and modulating factors of tissue Treg cell differentiation (CRC/Transregios)
- Completed projects
  - Rekrutierung von T-Zell-Subsets: Rolle von Antigen und Crosstalk mit Endothel (Collaborative Research Centres)
  - Regulation of Foxp3 Expression (CRC/Transregios)
  - Foxp3+ Tregs in mucosal tolerance: sites of de novo induction and stability under inflammatory conditions (Collaborative Research Centres)
  - Induction of specific homing receptors and of regulatory properties in mucosal T cells (Collaborative Research Centres)
  - Generation of stable, alloantigen-specific Foxp3+ regulatory T-cells (Collaborative Research Centres)
  - Control of immunological synapse formation in Tregs (Collaborative Research Centres)

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