Project Details

Professor Dr. Thomas Brabletz

Address Friedrich-Alexander-Universität Erlangen-Nürnberg
Nikolaus-Fiebiger-Zentrum für Molekulare Medizin
Lehrstuhl für Experimentelle Medizin I
Glückstraße 6
91054 Erlangen

Projects

As Applicant
- Current projects
  - Targeting the roots of cancer metastasis and therapy resistance (Reinhart Koselleck Projects)
  - Zeb1-mediated mechanisms of the EMT-associated ferroptosis sensitivity (Priority Programmes)
- Completed projects
  - The role of the oncoprotein ß-Catenin for invasion and metastasis formation of colorectal carcinomas (Research Grants)
  - Die Rolle des EMT-Aktivators ZEB1 bei Verlust von Zellpolarität und Akkumulation von Tumorstammzellen in kolorektalen Karzinomen (Research Grants)
  - Die Rolle der microRNA-200 Familie in der Tumorinvasion und Metastasierung (Research Grants)
  - Role of the EMT activator ZEB1 in pancreatic cancer invasion, dissemination and metastasis (Research Grants)
  - Interaction of the EMT-activator ZEB1 and the Yap/Taz/Hippo-pathway in cancer (Research Grants)
  - The role of the EMT-inducer Zeb1 in the invasive tumor stroma during colon cancer progression (Research Units)
  - Cancer promoting transcriptional enhancers controlled by the EMT-activator ZEB1 (Research Grants)
  - The role of the EMT-inducer Zeb1 in the invasive tumor stroma during colon cancer progression (Research Units)
As Project Head
- Current projects
  - Metabolic dysregulations in EMT-driven metastatic colonisation (CRC/Transregios)
  - Zeb1 expressing macrophages control metastatic colonisation (CRC/Transregios)
- Completed projects
  - NF-AT-Faktoren als Regulatoren der Expression pro- und anti-apoptischer Gene in Lymphozyten (Collaborative Research Centres)
  - Epigenetics and therapeutic options of EMT-associated drug resistance in pancreatic cancer (Collaborative Research Centres)
  - The role of the cadherin switch compared to Zeb1-dependent EMT in embryogenesis and tumor formation (Collaborative Research Centres)
  - Role of the EMT activator ZEB1 in pancreatic cancer invasion, dissemination and metastasis (Collaborative Research Centres)
As Participating Person
- Completed projects
  - Development of a cantilever sensor chip as a point-of-care (POC) device for label-free, rapid, and multiplexed detection of cancer protein biomarkers (Research Grants)

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Professor Dr. Thomas Brabletz

Additional Information

Servicenavigation

Hauptnavigation

Professor Dr. Thomas Brabletz

Additional Information

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