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Institution
Charité - Universitätsmedizin Berlin
Campus Benjamin Franklin (CBF)
Institut für Mikrobiologie und Infektionsimmunologie
Address
Hindenburgdamm 30
12203 Berlin
Deutschland
GERiT
This institution in GERiT
12203 Berlin
Projects
Research Grants
Current projects
Molecular regulation of intestinal epithelial cell (IEC) differentiation and function – A novel role for the transcription factor c-Maf
(Applicant
Neumann, Christian
)
Myeloid cell subtype-specific functions in immune complex-driven nephritis
(Applicant
Stamatiades, Efstathios
)
Novel strategies for Osteoarthritis treatment based on innate LYMPhoid Cells modulation
(Applicant
Mattiola, Irene
)
Transgenerational impact of maternal diets by regulating RORγt activity in embryonic and postnatal ILC3
(Applicant
Diefenbach, Andreas
)
Completed projects
Control of adaptive immune responses by NKG2D-mediated innate immune activation
(Applicant
Diefenbach, Andreas
)
Prenatal antibiotic exposure and the origins offspring asthma susceptibility. (ORIGIN)
(Applicant
Conrad, Melanie Lynn
)
Priority Programmes
Current projects
SPP 1937: Innate Lymphoid Cells
(Spokesperson
Diefenbach, Andreas
)
Completed projects
Characterization of mononuclear phagocyte populations that mediate microbiota-ILC3 interactions
(Applicant
Diefenbach, Andreas
)
Coordination Funds
(Applicant
Diefenbach, Andreas
)
Epigenetic control of ILC3 plasticity
(Applicant
Diefenbach, Andreas
)
Mysm1 is a decision checkpoint regulator of Group2 innate lymphoid cell biology
(Applicant
Dürr, Claudia
)
Role of the transcription factor c-Maf in controlling the development and function of RORgt+ type 3 innate lymphoid cells
(Applicant
Neumann, Christian
)
The neuropeptide neuromedin U promotes atopic dermatitis via stimulation of ILC2s
(Applicant
Klose, Christoph Siegfried Niki
)
Research Units
Current projects
FOR 2599: Tissue type 2 responses: Mechanisms of induction and regulation
(Spokesperson
Roers, Axel
)
Completed projects
Differentiation of group 2 innate lymphoid cells and their role during homeostasis and type 2 inflammation
(Applicants
Diefenbach, Andreas
;
Klose, Christoph Siegfried Niki
)
Independent Junior Research Groups
Current projects
Regulation of type 2 immune responses via neuropeptides and neurotransmitters
(Applicant
Klose, Christoph Siegfried Niki
)
Collaborative Research Centres
Current projects
Innate immune circuits for bone maintenance and regeneration
(Project Heads
Diefenbach, Andreas
;
Triantafyllopoulou, Antigoni
)
Completed projects
Analysis of CD8 T cell responses in immunodeficient mice lacking the NKG2D receptor
(Project Head
Diefenbach, Andreas
)
Attenuation of an immune evasion strategy of tumours by histone deacetylase inhibitors
(Project Head
Diefenbach, Andreas
)
Integrated Research Training Group of Immunodeficiency (IRTG-IMM)
(Project Heads
Diefenbach, Andreas
;
Schamel, Wolfgang
)
Research Fellowships
Completed projects
Defining the immune cascade leading to Nod-like receptor mediated Type 2 immune responses
(Applicant
Dürr, Claudia
)
Innate immune regulation of metabolic homeostasis
(Applicant
Klose, Christoph Siegfried Niki
)
CRC/Transregios
Current projects
Adrenergic regulation of myeloid cells in chronic inflammation and neurodegeneration
(Project Head
Klose, Christoph Siegfried Niki
)
Dissecting the role of epithelial inflammasome activation in regulating immune responses in colitis
(Project Heads
Chang, Hyun-Dong
;
Radbruch, Andreas
;
Ronchi, Francesca
)
ILC3-myeloid cell crosstalk during homeostatic maintenance of the epithelial barrier and during IBD
(Project Heads
Diefenbach, Andreas
;
Triantafyllopoulou, Antigoni
)
Impact of epithelial dysfunction on neuro-immune crosstalk in IBD
(Project Heads
Becker, Christoph
;
Engel, Matthias
;
Klose, Christoph Siegfried Niki
;
Patankar, Ph.D., Jay
)
Microbiota-dependent expression of IL22 by group 3 innate lymphoid cells regulates skin mesenchymal and epithelial cell differentiation
(Project Heads
Diefenbach, Andreas
;
Wolz, Christiane
)
Completed projects
Antiviral IFNs and NK cells in COVID-19
(Project Heads
Bauer, Stefan
;
Diefenbach, Andreas
;
Opitz, Bastian
)
Pathogen recognition by taste and odorant receptors and coupling to BALT formation and epithelial remodeling
(Project Heads
Diefenbach, Andreas
;
Krasteva-Christ, Gabriela
;
Kummer, Wolfgang
)
Major Research Instrumentation
Completed projects
5 laser flow cytometer for the detection of 20 parameters with high throughput sampling unit
Confocal laser scanning microscope
WBP Fellowship
Current projects
The role of IL-17 signaling in the enteric nervous system for immune regulation, gut physiology and central nervous system sensation of intestinal IL-17 inflammation
(Applicant
Witkowski, Mario
)
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