Ruprecht-Karls-Universität Heidelberg
Centre for Organismal Studies (COS)
Address
Im Neuenheimer Feld 230
69120 Heidelberg
Deutschland
GERiT
This institution in GERiT
69120 Heidelberg
Projects
Research Grants
Current projects
Cysteine biosynthesis acts as a regulatory hub for ABA-mediated stomatal closure
(Applicants
Hell, Rüdiger
;
Wirtz, Ph.D., Markus
)
Deciphering Heterogeneity in Drosophila multi-nucleated Muscles by decoding Gene Regulatory Networks active in Single Muscle Nuclei
(Applicants
Lohmann, Ingrid
;
Velten, Britta
)
Decoding Gene Regulatory Networks in single Drosophila Motoneurons
(Applicant
Lohmann, Ingrid
)
Determining mechanisms of phloem formation
(Applicant
Greb, Thomas
)
Elucidating the Role of Hox Transcription Factors in the Chromatin Context
(Applicant
Lohmann, Ingrid
)
Interactions of signalling pathways in genome maintenance during neurogenesis
(Applicant
Acebrón, Sergio Pérez
)
Regulation of cysteine partitioning into translation and stress responses.
(Applicants
Hell, Rüdiger
;
Wirtz, Ph.D., Markus
)
Species-Specific Timing of Neurogenesis
(Applicant
Centanin, Ph.D., Lazaro
)
Stress-induced regulation of N-terminal acetylation controls proteostasis in plants
(Applicants
Hell, Rüdiger
;
Wirtz, Ph.D., Markus
)
The role of SMXL7 in plant vessel formation
(Applicant
Greb, Thomas
)
The role of the centriolar CEP350 network in centrobin removal from centrioles and distal appendage/CEP19 recruitment
(Applicants
Pereira, Gislene
;
Schiebel, Elmar
)
Completed projects
Analysis of the developmental potencies of stem cells in Hydrozoa using mutants
(Applicant
Müller, Werner A.
)
Decisive Molecular Interactions in the early secretory pathway of plant cells
(Applicant
Robinson, David G.
)
Decoding the Lateral Expansion of Plant Stems
(Applicant
Greb, Thomas
)
Die Rolle der vakuolären Zuckertransporter des AtVGT-Typs während wichtiger Entwicklungsprozesse und Stressreaktionen
(Applicant
Büttner, Michael
)
Die Rolle von WNT/ß-Catenin-Signalsystemen bei der Etablierung der Körperachse und der Stammzellengenese bei Hydractinia (Cnidaria: Hydrozoa)
(Applicant
Müller, Werner A.
)
Dissection of general and specific regulatory mechanism of sulfur metabolism in Arabidopsis thaliana
(Applicants
Hell, Rüdiger
;
Wirtz, Ph.D., Markus
)
Elucidating the role of protein load for the physiology of Enterococcus faecalis by integrating proteomics data and genome-scale computational models
(Applicants
Fiedler, Tomas
;
Veith, Nadine
)
Fremderkennung und Gewebe(un)verträglichkeit bei dem marinen Hydroiden Hydractinia
(Applicant
Frank, Uri
)
Functional characterization of two new sugar transporter families within the Major Facilitator Superfamily (MFS)
(Applicant
Büttner, Michael
)
Function and regulation of the spindle positioning checkpoint (SPOC) kinase Kin4 of budding yeast
(Applicant
Pereira, Gislene
)
Funktion und Spezifität von Hox-Genen in der Determinierung von Segmentidentitäten entlang der anterior-posterioren (A/P) Achse von Drosophila-Embryonen
(Applicant
Lohmann, Ingrid
)
Genetic and circuit bases of mechanically-induced predator avoidance in Platynereis dumerilii larvae
(Applicant
Jékely, Gáspár
)
Hox Control of Morphogenesis via Co-Evolution of Numbers and Affinities of Hox Binding Sites with Transcription Factor Concentrations
(Applicant
Lohmann, Ingrid
)
KatNat_Elucidating the multifaceted functions of protein acetyltransferases in plant stress response and regulation of metabolism.
(Applicants
Finkemeier, Iris
;
Gibbs, Daniel
;
Giglione, Ph.D., Carmela
;
Wirtz, Ph.D., Markus
)
Mechanisms of neuropeptidergic regulation of larval settlement behavior in the marine worm, Platynereis dumerilii
(Applicant
Jékely, Gáspár
)
Modulation der `sink`-Aktivität durch koordinierte Expression von Invertase und Monosaccharid-Transporter in Arabidopsis
(Applicant
Büttner, Michael
)
Molecular analysis of ARGONAUTE7 function
(Applicant
Maizel, Alexis
)
Molecular and Behavioural Differences Between Homeostatic and Growth Stem Cells
(Applicant
Centanin, Ph.D., Lazaro
)
Molecular mechanisms of Hox specificity and functional diversity
(Applicant
Rogulja-Ortmann, Ana
)
Novel functions of the Drosophila Hox gene Ultrabithorax in central nervous system development
(Applicant
Rogulja-Ortmann, Ana
)
Proteomics analysis of endosomal compartments in Arabidopsis (ERA-PG 069)
(Applicants
Jürgens, Gerd
;
Robinson, David G.
)
Regulation and function of the Hox gene Ultrabithorax in the late embryonic central nervous system of Drosophila
(Applicant
Rogulja-Ortmann, Ana
)
Sorting and Transport of Proteins into the Dense Vesicle Pathway
(Applicant
Robinson, David G.
)
Sorting of seed storage proteins in developing seeds: Formation of transport vesicles and interdependence of different sorting pathways
(Applicant
Hinz, Giselbert
)
Studies of vacuolar transporters controlling nutrient storage and ion detoxification in Arabidopsis thaliana
(Applicant
Krebs, Melanie
)
Study of the interplay between the V-PPase and tonoplast-localise NHX antiporters in ion and pH homeostasis
(Applicant
Andres Gonzalez, Ph.D., Zaida Maria
)
Systems biology of cambium differentiation in Arabidopsis thaliana L.
(Applicant
Greb, Thomas
)
The functional role of protein O-mannosylation during eye development in zebrafish
(Applicant
Lommel, Mark
)
The regulatory function of the plant cysteine synthase protein complex for cellular cysteine homeostasis
(Applicant
Hell, Rüdiger
)
The Role of Hox Transcription Factors in Cellular Plasticity
(Applicant
Lohmann, Ingrid
)
The roles of Wnt-associated deubiquitinases
(Applicant
Acebrón, Sergio Pérez
)
Unraveling cellular and molecular mechanisms that coordinate pre- and postsynaptic maturation by intravital imaging in the Drosophila central nervous system
(Applicant
Evers, Jan Felix
)
Priority Programmes
Completed projects
Die Regulation von Monosaccharid-Transportern bei der Entwicklung und Funktion von Schließzellen und Wurzeln in Arabidopsis
(Applicant
Büttner, Michael
)
Functional characterization of vacuolar sugar transporter homologs
(Applicant
Büttner, Michael
)
Redox-sensitive switches in the core S-assimilation/GSH-biosynthetic pathway of plants
(Applicants
Hell, Rüdiger
;
Rausch, Thomas
;
Wirtz, Ph.D., Markus
)
Research Fellowships
Completed projects
Correlative cryogenic fluorescence and soft x-ray tomography of cells
(Applicant
Weinhardt, Venera
)
Funktion und Evolution von Hox-Genen
(Applicant
Lohmann, Ingrid
)
Suche nach Plasmodesma-assoziierten Proteinen in Arabidopsis thaliana mit Hilfe eines spezifischen Markerpeptids
(Applicant
Pott, Marcella
)
The establishment of the cambium-specific stem cell niche, which is being addressed by characterizing CBI1, a novel repressor of cambium identity in Arabidopsis thaliana
(Applicant
Suer, Stefanie
)
Uncovering the genetic basis for variation in adaptive responses to water deficit in Arabidopsis thaliana roots
(Applicant
Lindner, Heike
)
Research Units
Completed projects
Coordination Funds
(Applicant
Maizel, Alexis
)
Coordination Funds
(Applicant
Maizel, Alexis
)
FOR 2581: Quantitative Morphodynamics of Plants
(Spokesperson
Maizel, Alexis
)
Mechanisms and mechanics of lateral root initiation
(Applicant
Maizel, Alexis
)
Quantitative analysis of the cellular growth dynamics during lateral plant growth
(Applicant
Greb, Thomas
)
Support for data processing and management
(Applicant
Maizel, Alexis
)
The role of Vacuolar Hexose Exporters during Stress Response and Development
(Applicant
Büttner, Michael
)
Heisenberg Fellowships
Completed projects
Decoding Concepts of Multi-Cellularity and Growth Dynamics
(Applicant
Greb, Thomas
)
Molecular control of ciliogenesis
(Applicant
Pereira, Gislene
)
Heisenberg Professorships
Completed projects
Cellbiology
(Applicant
Pereira, Gislene
)
Decoding Concepts of Multi-Cellularity and Growth Dynamics
(Applicant
Greb, Thomas
)
Heisenberg Grants
Current projects
Comparative Mechanistic Analysis of Selective Autophagy in Plants
(Applicant
Dagdas, Ph.D., Yasin
)
Completed projects
Cell biology of microtubule-dependent processes
(Applicant
Pereira, Gislene
)
Emmy Noether Independent Junior Research Groups
Current projects
Kri-kri: A statically sound and accessible framework for causal regulatory inference from high-content CRISPR screens
(Applicant
Velten, Britta
)
The Cell biology of light signaling – What is the function of nuclear photobodies?
(Applicant
van Gelderen, Kasper
)
Understanding cell lineage plasticity in the development and evolution of vertebrate cranial cartilage
(Applicant
Saunders, Lauren
)
Major Research Instrumentation
Completed projects
confocal laser-scanning-microscope
Confocal Microscope with Laser Ablation
Multiview light sheet fluorescence microscope with laser ablation capacity
Single-objective light-sheet microscope
Transmissionselektronenmikroskop
Collaborative Research Centres
Current projects
Molecular specificity of ARGONAUTE action in ta-siRNAs biogenesis
(Project Head
Maizel, Alexis
)
Regulatory Specificity of Radial Plant Growth
(Project Head
Greb, Thomas
)
The roles of Wnt signaling in genome stability
(Project Heads
Acebrón, Sergio Pérez
;
Bastians, Holger
)
Wnt-cilia signaling in epithelial polarization and renal development
(Project Heads
Pereira, Gislene
;
Simons, Matias
)
Wnt pathway specificity in niche – stem cell control
(Project Heads
Bageritz, Josephine
;
Lohmann, Ingrid
)
Completed projects
Charakterisierung und Funktionsanalyse pfalnzlicher Clathrin- und COP-coated Vesikel
(Project Heads
Holstein, Susanne E.H.
;
Robinson, David G.
)
Functional role of centrosomes and cilia in stem cells
(Project Head
Pereira, Gislene
)
Mechanisms of niche – stem cell unit origin and maintenance
(Project Head
Centanin, Ph.D., Lazaro
)
Molecular and cellular control of the Drosophila male stem cell niche
(Project Head
Lohmann, Ingrid
)
Sensing and signaling integration in the surveillance mechanisms of the spindle position checkpoint
(Project Head
Pereira, Gislene
)
Spatio-temporal specificity of cambium stem cell signaling
(Project Head
Greb, Thomas
)
Stress-induced regulation of N-terminal acetylation controls proteostasis in plants
(Project Heads
Hell, Rüdiger
;
Wirtz, Ph.D., Markus
)
Zelluläre Mechanismen der Hox-abhängigen Morphogenese in Drosophila
(Project Head
Lohmann, Ingrid
)
Research Training Groups
Completed projects
GRK 388: Biotechnology: Biochemical and Molecular Foundation
(Spokesperson
Wink, Michael
)
GRK 484: Signalling Systems and Gene Expression in Developmental Model Systems
(Spokesperson
Pollerberg, Gabriele Elisabeth
)
Graduate Schools
Completed projects
GSC 249: The Hartmut Hoffmann-Berling International Graduate School of Molecular and Cellular Biology
(Spokesperson
Wittbrodt, Joachim
)
Clusters of Excellence (ExStra)
Current projects
EXC 2082: 3D Matter Made to Order (3DMM2O)
(Spokespersons
Bunz, Uwe F. H.
;
Selhuber-Unkel, Christine
;
Wegener, Martin
;
Wittbrodt, Joachim
)
