Universitätsklinikum Freiburg
Medizinische Mikrobiologie und Hygiene
Institut für Virologie
Address
Hermann-Herder-Straße 11
79104 Freiburg
Deutschland
GERiT
This institution in GERiT
79104 Freiburg
Projects
Research Grants
Current projects
The importance of cells which survive SARS-CoV-2 infection
(Applicant
Schwemmle, Martin
)
The role of CMV-encoded IgG binding glycoproteins in diaplacental virus transmission
(Applicant
Kolb, Philipp
)
Completed projects
Abwehr von Influenza- und Influenza-ähnlichen Viren durch Interferon: Bedeutung von Interferon-ß, Toll-like Rezeptoren und plasmacytoiden dendritischen Zellen
(Applicant
Stäheli, Peter
)
Analyse von Cytomegalovirus-kodierten Fcgamma-Rezeptoren (vFcgamma-R)
(Applicant
Hengel, Hartmut
)
Analysis of SARS-CoV-2 intra host evolution in immunocompromised individuals: A potential source of immune escape variants
(Applicants
Panning, Marcus
;
Warnatz, Klaus
)
Antiviral function of the human MxA protein and its association with the viral nucleocapsid
(Applicant
Kochs, Georg
)
Characterisation of an novel interferon antagonist of Thogoto virus
(Applicant
Kochs, Georg
)
Diversity of forests affecting human health
(Applicants
Bonn, Aletta
;
Bruelheide, Helge
;
Scherer-Lorenzen, Michael
)
Einsatz konfokaler Laser-Scanning-Mikroskopie zum Studium intrazellulärer Prozesse bei Virusinfektion und immunologischer Abwehr
(Applicant
Haller, Otto Albrecht
)
Elucidating the molecular mechanisms of MxB-mediated restriction of herpes virus infections
(Applicants
Kochs, Georg
;
Sodeik, Beate
)
Functional analysis of NS1 of highly pathogenic, mouse-adapted influenza A viruses in Mx1+/+ mice
(Applicant
Kochs, Georg
)
Functional analysis of the cGAS/STING axis during bacterial and viral infections and implications for the development of innovative vaccines
(Applicants
Kalinke, Ulrich
;
Ruzsics, Zsolt
)
Influence of the interferon system to control tick-transmitted Bourbon virus
(Applicant
Kochs, Georg
)
IRG- and GBP-specific virulence mechanisms of Toxoplasma gondii
(Applicant
Steinfeldt, Tobias
)
Molekularbiologische Charakterisierung der Orthomyxovirus-Replikation: Das ML-Protein von Thogoto-Virus als Interferon-Antagonist
(Applicant
Kochs, Georg
)
Molekulare Mechanismen der MxA-Virus-Interaktion
(Applicant
Kochs, Georg
)
Molekularer Mechanismus des La Crosse-Virus-induzierten Abbaus der zellulären RNA-Polymerase II
(Applicant
Kochs, Georg
)
Pathogenesis and immunity of Avian bornavirus infections in birds
(Applicant
Rubbenstroth, Dennis
)
Priority Programmes
Completed projects
Antivirally active factors of the type I interferon systems of small mammals
(Applicants
Kochs, Georg
;
Weber, Friedemann
)
Viral genes governing CMV capsid export
(Applicant
Koszinowski, Ulrich H.
)
Research Units
Current projects
FOR 2830: Advanced Concepts in Cellular Immune Control of Cytomegalovirus
(Spokesperson
Dölken, Lars
)
FOR 5200: Disrupt - Evade - Exploit: Gene expression and host response programming in DNA virus infection (DEEP-DV)
(Spokesperson
Brinkmann, Melanie
)
Human cytomegalovirus manipulation of HLA class I by US10
(Applicant
Halenius, Ph.D., Anne
)
Impact of HCMV-encoded FcγR antagonists on innate immune cell function
(Applicant
Hengel, Hartmut
)
Spatiotemporal regulation of host/viral chromatin remodeling complexes by Human Adenovirus (HAdV) determinants during early infection
(Applicant
Schreiner, Sabrina
)
Completed projects
Control of CD8+ T cells through interference of Cytomegalovirus with the "peptide loading complex" (PLC)
(Applicant
Hengel, Hartmut
)
Collaborative Research Centres
Completed projects
Analyse STAT-vermittelter hepatozellulärer Signalwege mittels viraler Antagonisten
(Project Head
Hengel, Hartmut
)
Analyse von Cytomegalovirus-kodierten Fcy-Rezeptoren (vFcyR)
(Project Head
Hengel, Hartmut
)
Antiviral factors and signal pathways in liver damage and regeneration
(Project Heads
Graf, Dirk
;
Hengel, Hartmut
;
Zimmermann, Albert
)
Kontrolle von MHC I Funktionen durch Mitglieder der HCMV US12 Genfamilie
(Project Head
Hengel, Hartmut
)
Räumliche und zeitliche Auflösung von Virusdynamik und Immunantwort bei Cytomegalovirus
(Project Heads
Koszinowski, Ulrich H.
;
Ruzsics, Zsolt
)
Research Fellowships
Completed projects
Identification of cellular restriction factors against herpesviral infection
(Applicant
Full, Florian Sebastian
)
Major Research Instrumentation
Completed projects
High Resolution Confocal light microscope with incubation chamber (Teilfinanzierung(
CRC/Transregios
Current projects
Determinants, dynamics and diversity of SUMO/PML nuclear bodies in the control of hepatitis B virus infection and cccDNA
(Project Heads
Nassal, Michael
;
Schreiner, Sabrina
)
Impact of neonatal CMV infection on lung macrophage development
(Project Heads
Henneke, Philipp
;
Ruzsics, Zsolt
)
Integrated Research Training Group “Immunovirology”
(Project Heads
Bauer, Tanja
;
Böttcher, Katrin
;
Hengel, Hartmut
;
Lohmann, Volker
;
Ruggieri, Ph.D., Alessia
;
Schreiner, Sabrina
)
Research Training Groups
Completed projects
GRK 1045: Modulation of Host Cell Functions to Treat Viral and Bacterial Infections
(Spokesperson
Dittmer, Ulf
)