Goethe-Universität Frankfurt am Main
Universitätsklinikum
Zentrum für Kinder- und Jugendmedizin
Klinik für Kinder- und Jugendmedizin
Address
Theodor-Stern-Kai 7
60596 Frankfurt am Main
Deutschland
GERiT
This institution in GERiT
60596 Frankfurt am Main
Projects
Emmy Noether Independent Junior Research Groups
Completed projects
Analyse nicht-kodierender RNAs als zentrale Regulatoren von Hämatopoese und Leukämogenese
(Applicant
Klusmann, Jan-Henning Cornelius
)
Research Grants
Current projects
Designing an engineered living material-based boosting ‘hub’ to maximize cytotoxicity of human immune cells against solid tumors
(Applicant
Yanamandra Guruvenkata, Archana Kaushik
)
Completed projects
Deciphering the complex, deregulated transcription network in the development of leukemia in children with Down syndrome
(Applicant
Klusmann, Jan-Henning Cornelius
)
Deciphering the genetic interactive network of the DLK1-DIO3 ncRNA locus in the hematopoietic system and in infant leukemias
(Applicant
Klusmann, Jan-Henning Cornelius
)
Investigating the role of the miR-125b target ARID3A in the pathology of myeloid leukemia associated with Down syndrome
(Applicants
Heckl, Dirk
;
Klusmann, Jan-Henning Cornelius
)
Role of oxidative stress in regulating cell death of lung cells and pulmonary disease in A-T
(Applicants
Schubert, Ralf
;
van Wijk, Sjoerd
)
Heisenberg Fellowships
Completed projects
From the pathogenesis to the therapy of infant leukemias
(Applicant
Klusmann, Jan-Henning Cornelius
)
Research Units
Current projects
Deciphering the genetically interactive network of the DLK1-DIO3 ncRNA locus in the hematopoietic system and in infant leukemias
(Applicant
Klusmann, Jan-Henning Cornelius
)
FOR 5433: RNA in focus (RIF): From mechanisms to novel therapeutic strategies in cancer treatment
(Spokesperson
Hüttelmaier, Stefan
)
FOR 5643: Clonal hematopoiesis: Pathomechanisms and clinical consequences in the heart and blood
(Spokesperson
Rieger, Michael
)
Rewiring leukemogenic transformation of GATA1s-mediated CH by KANSL1 loss-of-function mutations (Project B4)
(Applicants
Klusmann, Jan-Henning Cornelius
;
Vermunt, Ph.D., Marit
)
Targeting the non-coding stem cell signature in childhood acute myeloid leukemia
(Applicant
Klusmann, Jan-Henning Cornelius
)
Research Fellowships
Completed projects
Characterization of chromatin changes induced by Menin-MLL inhibition in NPM1c mutant acute myeloid leukemia
(Applicant
Uckelmann, Ph.D., Hannah
)
