Albert-Ludwigs-Universität Freiburg
BIOSS Centre for Biological Signalling Studies
Address
Schänzlestraße 18
79104 Freiburg
Deutschland
GERiT
This institution in GERiT
79104 Freiburg
Projects
Research Grants
Current projects
i2TCR-Research: Immunotherapies inspired by TCR Research
(Applicant
Minguet, Ph.D., Susana
)
Completed projects
Dissecting and manipulating regulatory feedback circuitry in Drosophila BMP morphogen signaling
(Applicant
Pyrowolakis, Giorgos
)
Downstream signaling mechanisms of phytochrome dimers
(Applicant
Ulbrich, Maximilian
)
Energetic investigations of induced particle uptake in functionalized, synthetic membrane systems.
(Applicants
Rohrbach, Alexander
;
Römer, Winfried
)
New fluorophores and labeling strategies for single molecule imaging
(Applicant
Ulbrich, Maximilian
)
OptoReg: Novel producer cells and processes based on optogenetic control circuits
(Applicants
Radziwill, Gerald
;
Takors, Ralf
)
Regulation of morphogen signaling at the plasma membrane: Novel components and interactions in the formation of graded BMP signaling in Drosophila wing imaginal discs
(Applicant
Pyrowolakis, Giorgos
)
Sex-specific alternative splicing in the head of Drosophila melanogaster and its underlying regulatory mechanisms
(Applicant
Pyrowolakis, Giorgos
)
Stoichiometry of the AMPA receptor´s assembly with regulatory membrane proteins
(Applicant
Ulbrich, Maximilian
)
The role of the biophysical properties of the tumor stroma in T-cell infiltration and anti-tumoral responses
(Applicant
Minguet, Ph.D., Susana
)
The role of the lectin LecB in the interaction of Pseudomonas aeruginosa with epithelia
(Applicant
Römer, Winfried
)
Understanding the molecular mechanism of chromosome segregation by the Escherichia coli Min system
(Applicant
Di Ventura, Ph.D., Barbara
)
Research Units
Current projects
FOR 2799: Receiving and Translating Signals via the gamma-delta T Cell Receptor
(Spokesperson
Prinz, Immo
)
Improving γδ T cell-based immunotherapy against cancer by studying signal initiation of the γδTCR
(Applicant
Minguet, Ph.D., Susana
)
Heisenberg Grants
Current projects
Understanding T cells to develop novel Immunotherapies
(Applicant
Minguet, Ph.D., Susana
)
Collaborative Research Centres
Current projects
Caveolin-1 and Filamin A: a novel mechanistic axis regulating B cell responses and immunopathology
(Project Head
Minguet, Ph.D., Susana
)
Optogenetic Control of Heterocellular Contributions to Cardiac Excitation and Arrhythmogenesis
(Project Heads
Schneider-Warme, Franziska
;
Di Ventura, Ph.D., Barbara
)
Targeting oncogenic hubs of solid tumours to overcome immune evasion from adoptive T cell transfer
(Project Head
Minguet, Ph.D., Susana
)
Completed projects
Control of T cell motility by the biophysical properties of the tumor stroma
(Project Head
Minguet, Ph.D., Susana
)
Die Rolle des Transkriptionsfaktors BOB.1 in der B-Zellentwicklung
(Project Heads
Nielsen, Ph.D., Peter
;
Reth, Michael
)
Gezielte Aktivierung von Lymphozyten durch variante Antigenrezeptoren
(Project Head
Reth, Michael
)
Modification and adaptor function of the B cell signaling proteins Syk and SHP-1
(Project Head
Reth, Michael
)
N02: Developmental biology involving mechanisms of pattern formation, signaling and differentiation in embryogenesis and organogenesis of animal or plant models
(Project Head
Pyrowolakis, Giorgos
)
Production and analysis of B-cell mutant mice with the Cre/loxP method
(Project Head
Reth, Michael
)
Rekonstitution der Signalkaskaden vom B Zell Antigenrezeptor
(Project Head
Reth, Michael
)
Struktur des B Zell-Antigenrezeptors und dessen Kopplung an Transducer Proteine
(Project Heads
Huber, Michael
;
Reth, Michael
)
Research Fellowships
Completed projects
Decoding the role of Netrin-1 receptor shedding during cancer cell survival
(Applicant
Nikodemus, Ph.D., Denise
)
Messung der Wechselwirkung von spannungs- und ligandengesteuerten Domänen in HCN-Ionenkanälen
(Applicant
Ulbrich, Maximilian
)
CRC/Transregios
Completed projects
The resting state of B lymphocytes and their Transition into early and late activation stages
(Project Heads
Minguet, Ph.D., Susana
;
Reth, Michael
)
The role of phosphatases in B cell autoimmunity
(Project Heads
Reth, Michael
;
Warscheid, Bettina
)
Priority Programmes
Completed projects
Shedding light on myogenesis: using optogenetics to investigate myoblast differentiation and muscle regeneration
(Applicants
Kassel, Olivier
;
Di Ventura, Ph.D., Barbara
)
Major Research Instrumentation
Completed projects
Fluorescence/patch clamp setup
Research Training Groups
Current projects
GRK 2202: Transport across and into membranes
(Spokesperson
Friedrich, Thorsten
)
Completed projects
GRK 1104: From Cells to Organs: Molecular Mechanisms of Organogenesis
(Spokesperson
Neubüser, Annette
)
International Research Training Groups
Completed projects
GRK 1642: Soft Matter Science: Concepts for the Design of Functional Materials
(Spokesperson
Reiter, Günter
)
Graduate Schools
Completed projects
GSC 4: Molecular Cell Research in Biology and Medicine (MOBILMED)
(Spokesperson
Borner, Christoph
)
Clusters of Excellence
Completed projects
EXC 294: Centre for Biological Signalling Studies (bioss) - From Analysis to Synthesis
(Spokesperson
Reth, Michael
)
