Freie Universität Berlin
Fachbereich Veterinärmedizin
Institut für Virologie (WE05)
Address
Robert-von-Ostertag-Straße 7-13
14163 Berlin
Deutschland
GERiT
This institution in GERiT
14163 Berlin
Projects
Research Grants
Current projects
Deciphering the role of telomeric repeats encoded by Marek’s disease virus-vaccines in latency, integration and protection against disease
(Applicant
Kaufer, Ph.D., Benedikt Bertold
)
The role of acylation of Gp5/M of porcine reproductive and respiratory syndrome virus for assembly and budding of virus particles elucidated by super resolution microscopy.
(Applicants
Kummer, Susann
;
Veit, Michael
)
Completed projects
Arriving at an in-depth understanding of equine herpesvirus type 1 and 4 (EHV-1 & EHV-4) disease: The role of mononuclear cells in viral pathogenesis
(Applicant
Osterrieder, Nikolaus
)
Attenuation of a highly virulent oncogenic herpesvirus by computer-aided virus reengineering
(Applicant
Osterrieder, Nikolaus
)
Biologische Sicherheit zellulärer porciner Xenotransplantate
(Applicant
Denner, Joachim
)
Biosynthese, Sortierung und Protein-Protein-Interaktionen von SNARE-Proteinen in vivo: Untersuchungen mit GFP-Fusionsproteinen in transfizierten Neuronen
(Applicant
Veit, Michael
)
Deciphering the mechanism of the viral telomerase RNA in Marek’s disease virus pathogenesis and tumorigenesis
(Applicant
Kaufer, Ph.D., Benedikt Bertold
)
Down regulation of MHC class I cell surface expression in Marek's disease virus (MDV) infection and its relevance in vivo
(Applicant
Osterrieder, Nikolaus
)
Equines Arteritis Virus (EAV): Identifizierung und Funktion der am Zelleintritt von EAV beteiligten viralen und zellulären Membranproteine
(Applicant
Veit, Michael
)
Function of ankyrin repeat proteins in cowpox virus (CPXV)
(Applicant
Osterrieder, Nikolaus
)
Funktion der Protein-Palmitoylierung während der regulierten Sekretion in neuro-endokrinen Zellen
(Applicant
Veit, Michael
)
Funktion des Glykoproteins M (gM) des Equinen Herpesvirus 1 (EHV-1) in Virus-Egress und Zell-zu-Zellausbreitung der Infektion
(Applicant
Osterrieder, Nikolaus
)
Identification of mechanisms underlying the attenuation of viruses by codon pair deoptimization
(Applicant
Veit, Michael
)
Palmitoylation of Influenza virus hemagglutinin: search for DHHC-acyltransferases in human airway cells as potential targets for new antiviral drugs.
(Applicant
Veit, Michael
)
Processing and Function of the Gp2/3/4 Spike of the Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)
(Applicant
Veit, Michael
)
Proteome analysis of lymphocytes after infection and transformation by the oncogenic Mareks Disease Virus.
(Applicants
Karger, Axel
;
Kaufer, Ph.D., Benedikt Bertold
)
Recoding the SARS-CoV-2 genome - A multidisciplinary approach to generate live-attenuated coronavirus vaccines
(Applicants
Beer, Martin
;
Kaufer, Ph.D., Benedikt Bertold
)
S-Acylation of hemmagglutinin of influenza virus with different fatty acids - structural requirements and functional consequences
(Applicant
Veit, Michael
)
Structure and function of Gp3 of porcine reproductive and respiratory syndrome virus
(Applicant
Veit, Michael
)
The role of the GP5-M Spike of the Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) for virus budding and viral persistence
(Applicants
Osterrieder, Nikolaus
;
Veit, Michael
)
The role of the secreted glycoprotein G in equine herpesvirus type 1 (EHV-1) immune modulation and virulence
(Applicant
Osterrieder, Nikolaus
)
Untersuchung potentieller PERV-Transmission auf humane Endothelien in einem Schwein-auf-Javaner-Affen Xenotransplantationsmodell
(Applicant
Denner, Joachim
)
Utilization of the CRISPR/Cas9 systems to protect chickens against Mareks disease virus and as a tool to dissect virus pathogenesis
(Applicants
Kaufer, Ph.D., Benedikt Bertold
;
Schusser, Benjamin
)
Viral factors involved in Marek's disease virus (MDV) genome integration
(Applicant
Kaufer, Ph.D., Benedikt Bertold
)
Research Units
Current projects
Coordination Funds
(Applicant
Kaufer, Ph.D., Benedikt Bertold
)
FOR 5130: ImmunoChick- Unravelling the avian immune response in the context of infection
(Spokesperson
Kaufer, Ph.D., Benedikt Bertold
)
FOR 5200: Disrupt - Evade - Exploit: Gene expression and host response programming in DNA virus infection (DEEP-DV)
(Spokesperson
Brinkmann, Melanie
)
Role of T cell subsets in Marek’s disease virus pathogenesis
(Applicant
Kaufer, Ph.D., Benedikt Bertold
)
Role of the intercellular heterogeneity, epigenetics and viral factors in the decision between lytic replication and latency of human herpesvirus 6
(Applicant
Kaufer, Ph.D., Benedikt Bertold
)
Completed projects
Porcine endogenous retroviruses (PERVs) and xenotransplantation: Safety evaluation, diagnostics and inhibition by siRNA
(Applicant
Denner, Joachim
)
Priority Programmes
Completed projects
Lateral sorting of proteins into lipid-rafts and protein-protein interactions as prerequisite for assembly of influenza virus: A complementary biophysical approach on model membranes and living cells
(Applicants
Herrmann, Andreas
;
Veit, Michael
)
Out of the reservoir: identification and characterization of viral and host factors governing the pathobiology of zoonotic cowpox viruses
(Applicants
Beer, Martin
;
Osterrieder, Nikolaus
)
Collaborative Research Centres
Completed projects
Modular organisation of vesicle tethering to membranes: Analysis of structural features and regulation by protein palmitoylation
(Project Heads
Heinemann, Udo
;
Veit, Michael
)
Modulation of prevalence, pathogenesis and immune control of pathogenic procine viruses by treatment with E.faecium of zinc
(Project Heads
Osterrieder, Nikolaus
;
Schmidt, Michael F.G.
)
Specific recruitment of viral components and assembly of enveloped viruses
(Project Heads
Herrmann, Andreas
;
Veit, Michael
)
CRC/Transregios
Completed projects
Experimental pathology and in vivo-modelling of SARS-CoV-2 infection in different hamster species
(Project Heads
Gruber, Ph.D., Achim Dieter
;
Trimpert, Jakob
)
Microbiological safety including virological safety
(Project Heads
Denner, Joachim
;
Godehardt, Antonia Wiga
;
Kaufer, Ph.D., Benedikt Bertold
;
Tönjes, Ralf R.
)
Research Training Groups
Completed projects
GRK 1121: Genetic and Immunologic Determinants of Pathogen-Host-Interactions
(Spokesperson
Lucius, Richard
)
