Project Details
Projekt
GRK 1167: Cell-cell Communication in Neural and Immune Systems: Topological Organisation of Signal Transduction
Subject Area
Neurosciences
Medicine
Medicine
Term
from 2005 to 2014
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 812229
Communication between cells is an essential biological function in multi-cellular organisms. Various basic mechanisms of cell-cell communication have evolved during phylogenesis, which were subject to organ-, tissue and cell type-specific adaptation. It is the aim of the Research Training Group to study and compare molecular mechanisms of cellular communication and signal transduction in the immune and the nervous systems, and to qualify students of the programme for top-level research by interdisciplinary education in both biological fields. The programme is based on the scientific potential of the two major biomedical research areas established in Magdeburg, i.e. Immunology and Neurosciences, which both are highly recognised at the international level. The programme includes scientists from the faculties of Medicine and Natural Sciences of the Otto von Guericke University and from the Leibniz Institute for Neurobiology.
The 14 projects address questions concerning
-- molecular mechanisms of communication between cells of the immune system,
-- immune response mechanisms in epithelial cells,
-- chemical synapses as key structures for communication between nerve cells, and
-- further molecular mechanisms of communication between neural cells.
Moreover, it is planned to study molecular interactions between neural and immune cells. All projects aim at performing basic immunological or neurobiological research; some of them are based on pathological observations and focus on the investigation of molecular mechanisms of medically relevant dysfunction of cell-cell communication and signal transduction.
The study programme aims at qualifiying graduate students to perform independent high-quality scientific research in the fields of neuroscience and immunology. The technology and the methods required for the different projects are related and thus constitute additional synergistic elements in education and research. Furthermore, key technologies including proteomics and bioinformatics is made available to all graduate students of the programme. Altogether, the Research Training Group constitutes a focus and an integrating element for future cooperation of the two involved research areas and shall back up and stimulate internationally recognised immunological, neurobiological and neuroimmunological research in Magdeburg.
The 14 projects address questions concerning
-- molecular mechanisms of communication between cells of the immune system,
-- immune response mechanisms in epithelial cells,
-- chemical synapses as key structures for communication between nerve cells, and
-- further molecular mechanisms of communication between neural cells.
Moreover, it is planned to study molecular interactions between neural and immune cells. All projects aim at performing basic immunological or neurobiological research; some of them are based on pathological observations and focus on the investigation of molecular mechanisms of medically relevant dysfunction of cell-cell communication and signal transduction.
The study programme aims at qualifiying graduate students to perform independent high-quality scientific research in the fields of neuroscience and immunology. The technology and the methods required for the different projects are related and thus constitute additional synergistic elements in education and research. Furthermore, key technologies including proteomics and bioinformatics is made available to all graduate students of the programme. Altogether, the Research Training Group constitutes a focus and an integrating element for future cooperation of the two involved research areas and shall back up and stimulate internationally recognised immunological, neurobiological and neuroimmunological research in Magdeburg.
DFG Programme
Research Training Groups
Applicant Institution
Otto-von-Guericke-Universität Magdeburg
Spokesperson
Professor Dr. Michael Naumann
Participating Researchers
Professorin Dr. Daniela C. Dieterich; Professor Dr. Klaus-Dieter Fischer; Professor Dr. Thomas Fischer; Professor Dr. Eckart D. Gundelfinger; Dr. Stefanie Kliche; Dr. Michael R. Kreutz; Professor Dr. Martin Leverkus (†); Professor Dr. Volkmar Leßmann; Dr. Thomas Munsch; Professor Dr. Georg Reiser; Professor Dr. Dirk Schlüter; Professor Dr. Burkhart Schraven; Professorin Dr. Constanze Seidenbecher; Professor Dr. Luca Simeoni; Professor Dr. Oliver Stork
