Structure-function analyses of NAC transcription factor proteoforms (A01)

Subject Area Plant Genetics and Genomics
Biochemistry
Plant Biochemistry and Biophysics
Bioinformatics and Theoretical Biology
Biophysics
Evolution and Systematics of Plants and Fungi
Plant Physiology
Structural Biology
Plant Cell and Developmental Biology
Cell Biology
Term since 2024
Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 514901783
 

Project Description

A01 investigates NAC transcription factors and aims to explore functional diversification between proteoforms, particularly in less structured C-terminal regions. By combining plant molecular biology and structural biochemistry, the project assesses NAC proteoforms for DNA sequence affinity, specificity, and protein interactions. NMR studies are crucial for understanding structure-function relationships. The project specifically examines NACs related to secondary cell wall synthesis and stress responses, revealing differences in target gene activation.
DFG Programme Collaborative Research Centres
Subproject of SFB 1664:  Plant Proteoform Diversity - SNP2Prot
Applicant Institution Martin-Luther-Universität Halle-Wittenberg
Project Heads Professor Dr. Jochen Balbach; Dr. Carolin Delker