TRR 298:  Safety Integrated and Infection Reactive Implants

• Subject Area: Materials Science and Engineering ; Biology ; Chemistry ; Computer Science, Systems and Electrical Engineering ; Mechanical and Industrial Engineering ; Medicine ; Social and Behavioural Sciences
• Term: since 2021
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 426335750

No abstract available

• DFG Programme: CRC/Transregios

Current projects

• A01 - Implant safety through individualisation of revision and regeneration of primary prosthetic components (Project Heads Denkena, Berend ;  Dittrich, Marc-André ;  Ettinger, Max ;  Tücking, Lars-René ;  Wichmann, Marcel )
• A02 - Mechanisms of implant failure during aseptic loosening of hip endoprostheses (Project Heads Hoffmann, Andrea ;  Melk, Ph.D., Anette ;  Stukenborg-Colsman, Christina )
• A03 - New diagnostic methods to detect loosened hip arthroplasties (Project Heads Behrens, Bernd-Arno ;  Jakubowitz, Eike ;  Zimmermann, Stefan )
• A04 - Demand-oriented design and manufacture of damage-tolerant implant junctions (Project Heads Bergmann, Benjamin ;  Denkena, Berend ;  Hurschler, Christof ;  Krödel-Worbes, Alexander )
• A05 - Sensory cochlea electrode: Sensory safety through detection of critical processes at the electrode-nerve interface (Project Heads Lenarz, Thomas ;  Maier, Hans Jürgen )
• A06 - Detection of cell occupation on cochlear implants and implant position for atraumatic insertion and long-term monitoring of stimulation efficiency (Project Heads Maier, Ph.D., Hannes ;  Zimmermann, Stefan )
• A07 - Surrogate-modelling for monitoring of implants (Project Heads Budde, Stefan ;  Nackenhorst, Udo ;  Nogueira, Waldo )
• A08 - Tissue-conserving hip and knee arthroplasty removal (Project Heads Nürnberger, Florian ;  Windhagen, Henning )
• B01 - Autonomous chemical and cell-based sensor-actuator systems for the detection and combat of implant-associated infections (Project Heads Menzel, Henning ;  Stiesch, Meike ;  Wirth, Dagmar )
• B02 - Uncovering of molecular mechanisms involved in biofilm-associated peri-implant infections (Project Heads Häußler, Susanne ;  Stiesch, Meike )
• B03 - Optical sensors for responsive implants (Project Heads Heisterkamp, Alexander ;  Nikutta, Katharina ;  Scheper, Thomas )
• B04 - Active stimulus-responsive implants (Project Heads Klose, Christian ;  Maier, Hans Jürgen ;  Pott, Philipp-Cornelius )
• B05 - Autonomous sequential drug release systems (Project Heads Behrens, Peter ;  Gellrich, Nils-Claudius ;  Polarz, Sebastian )
• B06 - Tracking and localised therapy of inflammation and infections on surfaces of established implants (Project Head Wirth, Dagmar )
• B07 - Simulation of biofilm growth and drug-induced degradation (Project Heads Szafranski, Szymon Piotr ;  Wriggers, Peter )
• B08 - Implant coating facilitating an intentional implant removal (Project Heads Behrens, Peter ;  Menzel, Henning ;  Polarz, Sebastian )
• Z01 - Trust and patient-centred communication as determinants of implant acceptance and compliance with advanced implant treatment (Project Heads Baumann, Eva ;  Klimmt, Christoph ;  Link, Ph.D., Elena )
• Z02 - Integrated research training group (IRTG) “Implant Technologies” (Project Heads Behrens, Peter ;  Melk, Ph.D., Anette ;  Wurz, Marc Christopher )
• Z03 - Central Task (Project Head Stiesch, Meike )

• Applicant Institution: Medizinische Hochschule Hannover
• Co-Applicant Institution: Gottfried Wilhelm Leibniz Universität Hannover
• Spokesperson: Professorin Dr. Meike Stiesch