Project Details
SFB 1430: Molecular Mechanisms of Cell State Transitions
Subject Area
Biology
Chemistry
Medicine
Chemistry
Medicine
Term
since 2021
Website
Homepage
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 424228829
No abstract available
DFG Programme
Collaborative Research Centres
Current projects
- A01 - Molecular control of kinetochore-microtubule interactions at the metaphase-anaphase transition (Project Head Westermann, Stefan )
- A02 - Bridging the gap between cell biology and biochemistry with artificial protein prosthetics in cell cycle transitions (Project Head Musacchio, Andrea )
- A03 - VCP/p97-cofactor complexes at the intersection of DNA repair and checkpoint control (Project Head Meyer, Hemmo )
- A04 - High-resolution electron microscopy of macro-molecular complexes in cell cycle regulation (Project Head Gatsogiannis, Christos )
- A05 - A molecular interface linking DNA replication with cell states of different replication Competence (Project Head Boos, Dominik )
- A06 - Implications of deregulated proteostasis in cell state transitions (Project Head Ehrmann, Michael )
- A07 - Golgi stress: impacting cell cycle transitions (Project Head Hellerschmied-Jelinek, Doris )
- A08 - Switching of spatio-temporal Rho GTPase signal network dynamics during cell cycle phase transitions (Project Head Nalbant, Ph.D., Perihan )
- A09 - Targeting oncogene-induced DNA repair pathway switches (Project Head Reinhardt, Christian )
- A11 - Molecular regulation of differentiation and cell cycle in tumor-repopulating melanoma cells (Project Head Roesch, Alexander )
- A12 - Mechanisms of locally controlled JARID1B histone demethylase activity (Project Head Pöpsel, Simon )
- A13 - IFNy-induced cell state transition in melanoma (Project Head Paschen, Annette )
- A14 - Metastatic transition in pancreatic ductal adenocarcinoma (Project Head Grüner, Barbara )
- B01 - Developing chemical tools for investigating cell state transitions (Project Head Kaiser, Markus )
- B02 - Chemical tools to dissect roles of deubiquitinases in cell state transitions (Project Head Gersch, Malte )
- B03 - Development of selective inhibitors and PROTACs for key signalling molecules regulating cell state transitions and the cell cycle (Project Head Knapp, Stefan )
- B04 - Hybrid computational strategies for the study of cell states (Project Head Sanchez Garcia, Elsa )
- INF - Research data management (RDM)– an integrated database and standardised analysis of ex-perimental data (Project Heads Meyer, Hemmo ; Rehwald, Stephanie ; Schulze, Nina )
- MGKiRTG - Integrated Research Training Group on “Molecular and Chemical Cell Biology” (Project Heads Nalbant, Ph.D., Perihan ; Westermann, Stefan )
- Z01 - Central Tasks of the Collaborative Research Centre (Project Head Meyer, Hemmo )
- Z02 - Detection and modulation of cell state transitions using advanced light microscopy (Project Head Schulze, Nina )
- Z03 - Central proteomics support (Project Head Kaschani, Farnusch )
Applicant Institution
Universität Duisburg-Essen
Spokesperson
Professor Dr. Hemmo Meyer