Epigenetic regulation of TFIID recruitment and activity
(A07)
Subject Area
General Genetics and Functional Genome Biology
Term
from 2018 to 2024
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 192904750
Epigenetic control of chromatin states is tightly linked to the transcriptional programmes of cells. The basal transcription factor TFIID acts at the crossroads between gene activation signals and RNA polymerase II transcription machinery. We aim to dissect the contributions of histone modifications and chromatin binding dynamics to the function of human promoters. The results of our study will provide a detailed understanding of the epigenetic mechanisms controlling gene transcription and differentiation in mammalian cells
DFG Programme
Collaborative Research Centres
