The impact of hypoxia pathway proteins on the adrenergic response in the adrenal gland and beyond (A02)

• Subject Area: Toxicology, Laboratory Medicine
• Term: since 2017
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 314061271

(I) Determine the impact of chronic exposure to systemic high/low glucocorticoid levels in adrenocortical-related HPP transgenic mice during haematopoiesis/erythropoiesis and local immune response.(II) Characterise the consequences of modulating central HPPs in chromaffin cells in mice.(III) Define the potential role of β2AR on haematopoietic cell lineages during (stress) haematopoiesis/ erythropoiesis.

• DFG Programme: CRC/Transregios
• Subproject of: TRR 205: The Adrenal: Central Relay in Health and Disease
• Applicant Institution: Technische Universität Dresden
• Project Heads: Professor Dr. Triantafyllos Chavakis, until 7/2021; Professor Dr. Ali El-Armouche; Professor Ben Wielockx, Ph.D.