Structural, process- and context-related factors mediating the renewal effect of extinction (A08+)

• Subject Area: General, Cognitive and Mathematical Psychology ; Human Cognitive and Systems Neuroscience
• Term: from 2017 to 2021
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 316803389

We will study factors that potentially influence the strength of the renewal effect of extinction: i.e. external (context-related) and internal (structural and process-related) potential moderators of renewal. By manipulating the saliency and generalizability of contexts, we aim to alter context processing and thus the level of renewal. By means of pharmacological intervention, we will modulate initial learning of associations to investigate potential effects upon renewal. Using various neuroimaging methods, we will relate task-associated activation in extinction-relevant brain regions, functional and structural connectivity as well as structural brain features to the propensity of showing renewal.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1280: Extinction Learning
• Applicant Institution: Ruhr-Universität Bochum
• Project Heads: Dr. Silke Lissek; Professor Dr. Martin Tegenthoff