Memory mechanisms of undernutrition in the gut ecosystem (C02)

• Subject Area: Gastroenterology ; Immunology ; Microbial Ecology and Applied Microbiology ; Metabolism, Biochemistry and Genetics of Microorganisms
• Term: since 2016
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 261376515

The goal of project C2 is to understand the long-lasting (memory) effects produced by undernutrition on the physiological host-microbial interplay in two different model organisms: Drosophila and mouse. Building on the accumulated findings, the project will develop a mechanistic framework for interventions to ameliorate the sustained effects of severe protein energy malnutrition episodes on organismal health, including targeted manipulation of the microbiota and/or metabolic processes.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1182: Origin and Function of Metaorganisms
• Applicant Institution: Christian-Albrechts-Universität zu Kiel
• Project Heads: Professor Dr. Thomas Roeder; Professor Philip Caspar Rosenstiel, Ph.D.