Membrane organization under strong curvature (A07)

• Subject Area: Statistical Physics, Nonlinear Dynamics, Complex Systems, Soft and Fluid Matter, Biological Physics
• Term: from 2011 to 2019
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 178321814

Using a concerted effort of simulations and x-ray experiments we will study the spatio-temporal organization of lipid membranes on different scales, considering three non-equilibrium situations: (A) the relaxation towards equilibrium after a shape change of a multi-component membrane, (B) the formation of metastable pre-pores in response to an external activation, and (C) the non-equilibrium, steady-state fluctuations of membranes with active proteins/pumps. In the simulations we will employ a multi-scale approach ranging from molecular dynamics simulations to augmented Helfrich-Hamiltonian models. The experiments will utilize sophisticated x- ray techniques.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 937: Collective Behaviour of Soft and Biological Matter
• Major Instrumentation: Microfocus source
• Instrumentation Group: 4090 Röntgenröhren und sonstige Röntgengeräte
• Applicant Institution: Georg-August-Universität Göttingen
• Project Heads: Professor Dr. Jörg Enderlein, until 12/2018; Professor Dr. Marcus Müller; Professor Dr. Tim Salditt