Project Details
Projekt
Lipidology of host cells and viral envelopes
Applicant
Professorin Dr. Britta Brügger
Subject Area
Virology
Term
from 2005 to 2013
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 13166150
We have developed a method by nano-ESI-MS/MS to qualitatively and quantitatively assess membrane lipids including each of their molecular species at the low picomole level. This method has opened the door to compare lipid compositions of membrane systems that, at a highly purified stage, are available only in minute quantities. This novel and hitherto not widely available method will be used to quantitatively analyse the lipid compositions of viral particles in order to compare them with their host membranes. These investigations are instrumental for our understanding of the molecular mechanisms that underlie formation of virus particles.
DFG Programme
Priority Programmes
Participating Person
Professor Dr. Felix Wilhelm Theodor Wieland
