Project Details

Professor Dr. Stefan Knapp

Address Goethe-Universität Frankfurt am Main
Fachbereich Biochemie, Chemie und Pharmazie
Institut für Pharmazeutische Chemie
Max-von-Laue-Straße 9
60438 Frankfurt am Main

Projects

As Applicant
- Current projects
  - Expanding the Functionality and Target Spectrum of Kinase Inhibitors using PROTACs (Research Grants)
- Completed projects
  - Exploration of SIK2-signaling in ovarian cancer with CCNE1-amplification3 (Research Grants)
  - Biochemical and structural studies on LRRK2 regulation. (Research Grants)
As Project Head
- Current projects
  - Development of selective inhibitors and PROTACs for key signalling molecules regulating cell state transitions and the cell cycle (Collaborative Research Centres)
  - Targeting key drivers in SCLC for the development of new therapeutic concepts (Collaborative Research Centres)
  - Targeting E3 ligase functions in AML (CRC/Transregios)
- Completed projects
  - Chemical biology analysis of epigenetics in SCLC (Collaborative Research Centres)
  - Structural characterization of domain-domain interactions in autophagy (Collaborative Research Centres)
  - Targeting selective autophagy in acute myeloid leukemia (Collaborative Research Centres)
As Co-Investigator
- Current projects
  - Covalent chemical probes for the neglected Ribosomal Protein S6 Kinase Beta 2 (S6K2) (Research Grants)
  - Exploring the brain permeation potential of natural product-inspired macrocycles (Research Grants)

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Professor Dr. Stefan Knapp

Additional Information

Servicenavigation

Hauptnavigation

Professor Dr. Stefan Knapp

Additional Information

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