Professor Dr. Oliver Schilling

Address Universitätsklinikum Freiburg
Institut für Klinische Pathologie
Breisacher Straße 115a
79106 Freiburg

Projects

As Applicant
- Current projects
  - Characterization and mode of action of Cochlin LCCL domain as a new host-targeted immunostimulating therapy against bacterial infections (Research Grants)
- Completed projects
  - System-wide identification of novel, bioactive substrates of matrix metalloprotease (MMP)-2 and dissection of a novel MMP-2 activation pathways (Emmy Noether International Fellowships)
  - Substrate Profiling of Cysteine Proteases in Physiology and Pathology (Emmy Noether Independent Junior Research Groups)
  - Processed Sonic hedgehog - an active signaling protease? (Research Grants)
  - Netherton Syndrome: From mechanisms to therapeutics (Research Grants)
  - Tracing the untackled facets of Peeling Skin Disease-Targeting epidermal proteolysis for treatment (Research Grants)
  - Proteolytic Determinants of Cellular Behavior in Health and Disease (Heisenberg Professorships)
  - Robust centrifugal microfluidic miniaturization and automation of target enrichment for protease substrate identification (Research Grants)
  - Impact of the aberrant cell-matrix interaction in Non-Alcoholic fatty liver diseases progression (Research Grants)
  - Proteomics and metabolomics systems analysis of envenomation by Bothrops snakes and antivenom effects using a murine model (Research Grants)
  - Functional and Translational Proteome Research (Heisenberg Grants)
As Leader
- Completed projects
  - Hybrid ESI/MALDI mass spectrometer with trapped ion mobility spectrometry (Major Research Instrumentation)
As Participating Researcher
- Current projects
  - GRK 2606: Understanding protease functions in cellular pathways through discovery and analysis of protease substrates (ProtPath) (Research Training Groups)
  - GRK 2344: MeInBio - BioInMe: Exploration of spatio-temporal dynamics of gene regulation using high-throughput and high-resolution methods (Research Training Groups)
- Completed projects
  - GSC 4: Molecular Cell Research in Biology and Medicine (MOBILMED) (Graduate Schools)
As Project Head
- Current projects
  - VHL-dependent licensing of hetero-cellular crosstalks within the tumor micro-environment of clear cell renal cell carcinoma (ccRCC) (Collaborative Research Centres)
- Completed projects
  - Integrating signaling networks of cell adhesion, cell motility, and tumor-stroma interactions (Collaborative Research Centres)
  - Systems biology, pathology and proteomics (Collaborative Research Centres)
As Co-Investigator
- Current projects
  - Proteom biology of peri-implant inflammation for perspective early detection (Research Grants)
  - Artificial Intelligence based Multiomics for Personalized Outcome Prediction after Radiation Therapy in Primary Prostate Cancer Patients (Research Grants)
- Completed projects
  - Cell-matrix interactions of renal tubular epithelial cells: implications of cortical actin structures and the tubular basement (Research Grants)