Professor Dr. Falk Nimmerjahn

Address Friedrich-Alexander-Universität Erlangen-Nürnberg
Department Biologie
Lehrstuhl für Genetik
Erwin-Rommel-Straße 3
91058 Erlangen

Projects

As Applicant
- Current projects
  - Deciphering the Function and Regulation of the B Cell Intrinsic a2,6-Sialylation Network (Research Units)
  - Understanding the Mincle-FcγR crosstalk in the regulation of autoantibody-dependent inflammation (Research Grants)
  - Role of the materno-fetal IgG bone marrow macrophage axis for early B cell development (Research Units)
- Completed projects
  - Untersuchungen zur molekularen Wirkung von Anti-Tumor-Antikörpern in in vivo Tumormodellen der Maus (Research Fellowships)
  - Einfluss deregulierter oder funktionell inaktiver inhibitorischer Rezeptoren auf die Aufrechterhaltung der Toleranz im humoralen Immunsystem der humanisierten Maus (Research Units)
  - Impact of immunoglobulin G and Fc-gamma-receptors on osteoblast and osteoclast development and function in vitro and in vivo (Priority Programmes)
  - The molecular basis and functional consequences of IgG subclass glycosylation (Research Grants)
  - Pathogenicity of IgA-type autoantibodies in pemphigoid disease (Research Grants)
  - Deciphering the stage specific impact of cellular and humoral components modulating the onset of RA (Research Units)
As Leader
- Completed projects
  - Zellanalyse- und Hochgeschwindigkeitssortiersystem (Major Research Instrumentation)
As Participating Researcher
- Completed projects
  - GRK 1660: Key Signals of Adaptive Immune Response (Research Training Groups)
As Project Head
- Current projects
  - Modulating the tumor metastasis propagating and inhibiting effects of tumor associated macrophages via Fc-receptors (CRC/Transregios)
  - Cell subset-specific roles of FcRn in regulating autoantibody generation and activity in pemphigoid diseases (Collaborative Research Centres)
  - Regulation of autoantibody in-duced bone inflammation and osteoclastogenesis via the C-type lectin receptor Mincle (CRC/Transregios)
- Completed projects
  - Investigating the mechanism of antibody mediated effector functions in vivo (Collaborative Research Centres)
  - Investigating the mechanism of antibody mediated effector functions in vivo (Collaborative Research Centres)
  - Deciphering the Regulation of the B Cell intrinsic Glycoslyation Network (CRC/Transregios)
  - Harnessing monocyte and dendritic cell dependent pathways of IVIg activity to enhance resolution of inflammation (Collaborative Research Centres)