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Project Details

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Professor Dr. Thorsten Hoppe

Address Universität zu Köln
Department für Biologie
Institut für Genetik
Zülpicher Straße 47a
50674 Köln

Projects

As Applicant
- Current projects
  - Stress-induced myosin folding and assembly mechanisms (Research Units)
  - Coordination of DNA damage response and aging by ubiquitin signaling (Research Units)
  - Coordination of proteostasis and mitochondrial intermembrane space protein import (Priority Programmes)
- Completed projects
  - Multiubiquitylation Pathways Involved in Muscle Assembly (Research Grants)
  - RP1: Identification of ubiquitin-dependent pathways involved in neuron-specific protein degradation (Research Units)
  - RP7: Investigation of novel mechanisms in degradation of aggregated neuroserpin (Research Units)
  - Challenging the ubiquitin proteolytic signal - Novel modes of modification and recognition (DIP Programme)
  - Regulation of Genome Maintenance by Chromatin-Associated Protein Degradation (Research Grants)
  - Ubiquitin-dependent regulation of the DNA damage-induced apoptosis and relevance for the chemoresistance of refractory CLL (Clinical Research Units)
As Leader
- Completed projects
  - Large-Particle Flow Cytometer (Major Research Instrumentation)
As Deputy
- Completed projects
  - FOR 885: Neuronal Protein Turnover (Research Units)
As Spokesperson
- Current projects
  - EXC 2030: CECAD - Excellent in Aging Research (Clusters of Excellence (ExStra))
As Participating Researcher
- Completed projects
  - EXC 229: Cellular Stress Responses in Aging-Associated Diseases (Clusters of Excellence)
As Project Head
- Current projects
  - Coordination of endoplasmic reticulum-associated fidelity machines (Collaborative Research Centres)
  - Ubiquitin-dependent coordination of mitochondrial-cytoplasmic quality control (Collaborative Research Centres)
- Completed projects
  - Neuronaler Proteinabbau (Collaborative Research Centres)
  - Substrate recruitment and ubiquitylation by E3 ligase complexes (Collaborative Research Centres)
  - KFO 286: Exploiting Defects in the DNA Damage Response for the Treatment of Chronic Lymphocytic Leukemia (Clinical Research Units)
As Participating Person
- Completed projects
  - The VHL/HIF-axis in the regulation of cellular stress resistance (Research Grants)

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