Professorin Dr. Anita Ignatius

Address Universitätsklinikum Ulm
Zentrum für Chirurgie
Institut für Unfallchirurgische Forschung und Biomechanik
Helmholtzstraße 14
89081 Ulm

Projects

As Applicant
- Current projects
  - Impact of Wnt1 mutation on skeletal remodeling, bone matrix quality, fracture healing and response to mechanical stimulation (Research Grants)
  - Molecular role of PIEZO1 in endochondral ossification (Research Grants)
- Completed projects
  - Ultraschalleffekte auf humane Knochenzellkulturen (Research Grants)
  - Entzündungsantwort von Knochenzellen nach muskulo-skeletalem Traume (Clinical Research Units)
  - Untersuchung der Frakturheilung in osteoporotischen Tiermodellen: Einfluss der Störung der zentralen Regulation der Knochenformation und der Wnt-abhängigen Signaltransduktion (Research Units)
  - Molekulare Charakterisierung der Störungen zellulärer Mechanotransduktion bei Osteoporose (Research Units)
  - Untersuchung der Frakturheilung bei Hypochlorhydrie-induzierter Osteoporose in Maus und Schwein (Research Units)
  - Bedeutung des Heparin-bindenden Polypeptids Midkine in der Regulation der Knochenmasse und der Frakturheilung (Research Grants)
  - Verbesserung der Frakturheilung durch O2-induzierte Modulation der posttraumatischen Entzündungsantwort (Clinical Research Units)
  - Bedeutung des Komplementsystems bei der Frakturheilungsstörung nach Polytrauma (Clinical Research Units)
  - Analysis of early immune responses and the role of mast cells in fracture healing (Priority Programmes)
  - Local remodelling and mechanoregulation of bone fracture healing in healthy, aged, and osteoporotic humans (Research Grants)
  - Deciphering the role of Piezo proteins in mechanotransduction of bone cells (Research Grants)
  - Synthesis, processing and in vivo degradation behaviour of magnesium phosphate minerals for bone replacement (Research Grants)
As Leader
- Completed projects
  - Analytischer Micro-Computertomograph (Major Research Instrumentation)
As Participating Researcher
- Completed projects
  - GSC 270: International Graduate School in Molecular Medicine Ulm (Graduate Schools)
As Project Head
- Current projects
  - Elucidating the pathomechanisms of compromised fracture healing in osteoporosis: Consequences of mitochondrial dysfunction (Collaborative Research Centres)
  - Osteoblast differentiation-stage specific mechanisms of glucocorticoid action during fracture healing (Collaborative Research Centres)
  - Central project for trauma modeling, monitoring and diagnostics (Collaborative Research Centres)
- Completed projects
  - Mechanisms of interleukin-6 action in trauma-induced impairment of bone regeneration (Collaborative Research Centres)
  - Trauma diagnostics (Collaborative Research Centres)
As Participating Person
- Completed projects
  - Mechanismen der Frakturheilung und Knochenregeneration bei Osteoporose (Research Units)
  - Mechano-biology of bone regeneration (Research Grants)
As Co-Investigator
- Current projects
  - Coupled analysis of active biological processes for meniscus tissue regeneration: Experiments, statistical data processing, and datainformed in-silico modeling (Priority Programmes)