Project Details

Professor Dr. Albert Jeltsch

Address Universität Stuttgart
Institut für Biochemie und Technische Biochemie
Abteilung Biochemie
Allmandring 31
70569 Stuttgart

ORCID-ID 0000-0001-6113-9290

Projects

As Applicant
- Current projects
  - Role of E2F1 methylation by SETD6 and identification of novel SETD6 methylation substrates (Research Grants)
  - Design and use of EpiEditors to mitigate alpha-synuclein overload in Parkinson’s disease and related synucleinopathies (Research Grants)
  - Investigation of the DNA interaction specificity of DNA methyltransferases and demethylases by deep enzymology (Research Grants)
  - New approaches to study the biological role of 6-methyladenine in human DNA (Research Grants)
  - Analysis of the protein lysine methylome of SARS-CoV-2 (Research Grants)
  - Development of synthetic, methylation based, epigenetic gene circuits (Research Grants)
- Completed projects
  - Biochemistry and biological function of mammalian Dnmt1 (Priority Programmes)
  - Interaction of mammalian de novo DNA methyltransferases with DNA and nucleosomes and regulatory proteins (Research Grants)
  - Directed evolution of DNA methyltransferases (Priority Programmes)
  - Structure, mechanism and function of bacterial DNA methyltransferases (Research Grants)
  - Biochemical characterization and molecular evolution of the Dnmt2 RNA/DNA metyltransferase (Research Units)
  - Mechanism and regulation of the Dnmt1 DNA methyltransferase (Research Grants)
  - Functional analysis of somatic cancer mutations in human DNA methyltransferases (Priority Programmes)
  - Specificity and novel substrates of human protein glutamine methyltransferases (Research Grants)
  - Biochemical characterization and biological role of the DNMT3A and DNMT3B de novo DNA methyltransferases (Research Grants)
  - Specificity analysis of human protein lysine methyltransferases and proteomwide identification of novel substrate proteins (Research Grants)
  - Application of single-enzyme kinetics to investigate the turnover rate, processivity and specificity of DNA methyltransferase 1 (Priority Programmes)
As Leader
- Completed projects
  - MALDI TOF MS/MS Massenspektrometer (Major Research Instrumentation)
As Deputy
- Completed projects
  - FOR 1082: Biochemistry and Biological Function of Dnmt2 Methyltransferases (Research Units)
As Participating Researcher
- Completed projects
  - GRK 370: Biochemistry of Nucloeprotein Complexes (Research Training Groups)

Servicenavigation

Hauptnavigation

Professor Dr. Albert Jeltsch

Additional Information

Servicenavigation

Hauptnavigation

Professor Dr. Albert Jeltsch

Additional Information

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