Project Details

Professor Dr.-Ing. Georg Duda

Address Charité Universitätsklinikum
Campus Virchow-Klinikum
Julius Wolff Institut für Biomechanik
und Muskuloskeletale Regeneration (CVK)
Augustenburgerplatz 1
13353 Berlin

Projects

As Applicant
- Current projects
  - In vivo mechanical loading and tissue adaptation in vertebrae: Inflammation, pain and opioid effects (Research Units)
- Completed projects
  - Entwicklung und Testung eines biomechanischen Modells für das Schafsbein zur Reduzierung und Optimierung von Tierversuchen zur Frakturheilung (Research Grants)
  - Quantifizierung des Einflusses von Gelenkersatz und Umstellungsosteotomien auf die muskuloskeletale Beanspruchung des Oberschenkels (Research Grants)
  - Beanspruchungsgerechte Osteosyntheseplanung komplexer, gelenkinvolvierender Frakturen der proximalen Tibia (Research Grants)
  - Beanspruchungsgerechte Osteosyntheseplanung komplexer Frakturen und Umstellungen der Tibia (Clinical Research Units)
  - Muskuloskelettale Belastung und biologische Antwort im validierten Schafsmodell (Clinical Research Units)
  - Service Biomechanik und Histomorphometrie (Clinical Research Units)
  - Druck und Kinematik im stabilen und instabilen Patellofemoralgelenk unter muskuloskeletaler Belastung (Research Grants)
  - Osteochondrale Defektheilung - Mechanobiologische und molekularbiologische Mechanismen der Regeneration (Research Grants)
  - Vom lebenden Material lernen, technische Materialien für die Geweberegeneration und für medizinische Implantate entwickeln (Nachwuchsakademie Medizintechnik 2010) (Workshops for Early Career Investigators)
  - Influence of biological factors on the mechanical regulation of tissue differentiation processes during large bone-defect healing. (Research Grants)
  - Interaction of biological and mechanical stimuli during bone defect healing: Identify the role of early inflammation as a key regulator of mechanically induced tissue regeneration (Research Grants)
  - Regeneration of tissue interfaces: Biomaterial controlled morphogen gradients for tissue patterning in regeneration (Research Grants)
  - Towards understanding long-term cartilage degeneration: The role of passive joint laxity and active joint instability in pathological knee kinematics (Research Grants)
  - Development of MR-based procedures and technologies for non-invasive in-vivo assessment of mechanical loading of tissues: Movement and straining of soft tissue structures using the knee joint as example system (Research Grants)
  - Mechano-dependency of early bone healing, angiogenesis, and their interplay across ages (Research Units)
  - Coordination Funds (Research Units)
  - Identification of Stresses in Heterogeneous Contact Models (Priority Programmes)
As Leader
- Completed projects
  - KFO 102: Biomechanics and Biology of Bone Healing: Individual, Load Adapted Osteosynthesis (Clinical Research Units)
As Spokesperson
- Current projects
  - SFB 1444: Directed Cellular Self-Organization to Advance Bone Regeneration (Collaborative Research Centres)
- Completed projects
  - SFB 760: Biomechanics and Biology of Musculoskeletal Regeneration - From Functional Assessment to Guided Tissue Formation (Collaborative Research Centres)
  - GSC 203: Berlin-Brandenburg School for Regenerative Therapies (BSRT) (Graduate Schools)
  - FOR 2165: Regeneration in Aged Individuals: Using Bone Healing as a Model System to Characterise Regeneration under Compromised Conditions (Research Units)
As Project Head
- Current projects
  - Mechano‐dependency of early bone healing, angiogenesis, and inflammation (Collaborative Research Centres)
  - Understand and shape bone regeneration by cellular metabolic adaptation in immune and stromal cells (Collaborative Research Centres)
  - Central Administrative Project ‐ Central tasks of the Collaborative Research Centre (Collaborative Research Centres)
- Completed projects
  - Mechano-biology of bone healing and regeneration (Collaborative Research Centres)
  - Biomechanical characterisation of bone healing and regeneration in small and large animals (Collaborative Research Centres)
  - Organisation and structural integration (Collaborative Research Centres)
  - Hydrogels with spatial patterning of biophysical and biochemical properties to guide osteogenesis (Collaborative Research Centres)
As Participating Person
- Completed projects
  - Quantifizierung des Einflusses von Gelenkersatz und Umstellungsosteotomien auf die muskuloskeletale Beanspruchung des Oberschenkels (Research Grants)
  - Entwicklung und Testung eines biomechanischen Modells für das Schafsbein zur Reduzierung und Optimierung von Tierversuchen zur Frakturheilung (Research Grants)
  - Die sezernierten Phosphatonine FGF23 und sFRP4 - ihre Bedeutung bei der osteogenen Differenzierung, im Phosphatstoffwechsel und ihr therapeutisches Potential für das Tissue Engineering (Clinical Research Units)
  - Korrelation von in vivo interfragmentärer Bewegung und Beanspruchung mit dem klinischen Heilungsergebnis (Clinical Research Units)
  - Prognose der Frakturheilung anhand knochenspezifischer Parameter unter Berücksichtigung der mechanischen Rahmenbedingungen in vivo (Clinical Research Units)
  - Einfluss mechanischer und biologischer Stimulation auf Osteoklasten, Osteoblasten und deren Co-Kultur in vitro (Clinical Research Units)
  - Initiale Phase der Knochenheilung: Inflammation und Organisation (Research Grants)
  - Immunologische Charakterisierung der initialen Phase des Frakturhämatoms beim Menschen (Research Grants)
As Co-Investigator
- Current projects
  - Influence of local tissue injuries, repair and degeneration on spinal Morphology, Mechanics and Motion in a large animal model (Research Units)
- Completed projects
  - Resolution of inflammation in tendon disease: how is the bursa involved? (Research Grants)
  - Laying the foundations towards understanding physiological kinematics after Total Knee Arthroplasty (Research Grants)

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Professor Dr.-Ing. Georg Duda

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Professor Dr.-Ing. Georg Duda

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