Professor Dr. Marcus Groettrup (†)
Projects
As Applicant
Completed projects
NUB-1 - a new interaction partner of the ubiquitin-like protein FAT10 with a novel function in proteolytic targeting
(Research Grants)
Proteasome molecular composition, biosynthesis, turnover and function during viral infection
(Research Grants)
The Mechanisms of cross-presentation of a long-lived viral protein
(Research Grants)
Localization and intracellular trafficking of the chemokine receptor CCR7 after ligand mediated signal transduction and chemotaxis
(Research Grants)
The function of UBEIL2, a novel ubiquitin specific activating enzyme (E1)
(Research Grants)
Molecular regulation and functional efficacy of T cell responses in a mouse model of social stress and patients with post-traumatic stress disorder (PTSD)
(Research Units)
The ubiquitin-like modifier FAT10 in autophagosomal targeting
(Research Grants)
The function of immunoproteasomes in cytokine production and autoimmune diseases
(Research Grants)
The role of the ubiquitin-like protein FAT10 in thymic selection
(Priority Programmes)
Identification of Immunoproteasome dependent factors involved in cytokine release and T cell differentiation
(Research Grants)
As Leader
Completed projects
Durchflusszytometer (5 Laser)
(Major Research Instrumentation)
As Participating Researcher
Current projects
EXC 2117: Centre for the Advanced Study of Collective Behaviour
(Clusters of Excellence (ExStra))
Completed projects
GRK 702: Biomedical Drug Research
(Research Training Groups)
GRK 1331: Cell-based Characterisation of Disease Mechanisms in Tissue Destruction and Repair
(Research Training Groups)
GSC 218: Konstanz Research School Chemical Biology (KoRS-CB)
(Graduate Schools)
As Project Head
Completed projects
Regulation of CCR7 signalling and lipid raft association in dendritic cells through prostaglandin E2
(CRC/Transregios)
Localization and intracellular trafficking of the chemokine receptor CCR7 after ligand mediated signal transduction and chemotaxis
(CRC/Transregios)
The substrates of FAT10ylation and their proteolytic targeting
(Collaborative Research Centres)
The structural and functional consequences of FAT10 phosphorylation
(Collaborative Research Centres)
As Participating Person
Completed projects
Development of a prostate cancer DNA-vaccine
(Research Grants)
As Ehemaliger Antragsteller
Current projects
Therapy of prostate carcinoma by immunoproteasome inhibition
(Research Grants) to 12/2022
Completed projects
Regulation of 26S proteasome activity and coping with protein aggregation diseases by NUB1
(Research Grants) to 9/2022
