Professor Dr. Andreas Mackensen

Address Universitätsklinikum Erlangen AöR
Medizinische Klinik 5 - Hämatologie und Internistische Onkologie
Ulmenweg 18
91054 Erlangen

Projects

As Applicant
- Completed projects
  - Immune-regulatory function of human CD3 CD4-/CD8- double negative T cells (Research Grants)
  - Immunregulatorische Funktionen humaner TCRáâ+ CD4-CD8- doppelt negativer T-Zellen (Clinical Research Units)
  - Suppression of human T cells by 5'-methylthioadenosine (Clinical Research Units)
  - Importance of aberrant double negative T-cells in patients with autoimmune lymphoproliferative syndrome (ALPS) (Research Grants)
As Participating Researcher
- Completed projects
  - GRK 1660: Key Signals of Adaptive Immune Response (Research Training Groups)
As Project Head
- Current projects
  - Metabolic stress related immune alterations with impact on graft-versus-leukemia effect in allogeneic stem cell transplantation (CRC/Transregios)
- Completed projects
  - Tumor-Immuntherapie durch Vakzinierung mit tumorantigen-beladenen dendritischen Zellen und adoptiven T-Zell-Transfer (Collaborative Research Centres)
  - Immuntherapie beim malignen Melanom mit tumorpeptidbeladenen, autologen dendritischen Zellen (Collaborative Research Centres)
  - Adoptive transfer of CMV/EBV multi-epitope specific T-cells for prevention and treatment of virus reactivation in patients after matched allogeneic stem cell transplantation (Collaborative Research Centres)
  - Immunoregulatory Function of Human TCRαβ+ CD4-/CD8- Double Negative T cells and its Potential Role in Limiting Auto- and Alloreactive Immune Responses (Collaborative Research Centres)
As Participating Person
- Completed projects
  - Antigenspezifische Elimination von primären humanen CD4+ und CD8+ T-Zellen durch Apoptose-induzierte artifizielle antigenpräsentierende Zellen in vitro (Research Grants)
  - Modulation der Differenzierung und Aktivierung dendritischer Zellen durch das Tumormilieu - Untersuchungen in einem dreidimensionalen Tumorsphäroid Kokultur Modell (Research Grants)