Albert-Ludwigs-Universität Freiburg
Klinik für Urologie
Arbeitsgruppe Hormone Dependent Cancer
Address
Breisacher Straße 66
79106 Freiburg
Deutschland
GERiT
This institution in GERiT
79106 Freiburg
Projects
Research Grants
Current projects
Understanding the relevance of RAI2 activity in emerging therapy-resistance of castration-resistant prostate cancer
(Applicants
Pantel, Klaus
;
Werner, Stefan
)
Completed projects
Charakterisierung der Histondemethylase LSD1
(Applicant
Schüle, Roland
)
Die Regulation des Tumorsuppressors p53 durch den neuen INHAT-Repressor NIR
(Applicants
Roemer, Klaus
;
Schüle, Roland
)
FHL2 modulierte Osteoblastenaktivität: Ein neuer Weg zur Inhibition von Osteoporose
(Applicants
Günther, Thomas
;
Schüle, Roland
)
FHL2 modulierte Osteoblastenaktivität: Ein neuer Weg zur Inhibition von Osteoporose
(Applicant
Schüle, Roland
)
Funktionelle Charakterisierung der Transkriptionsfaktoren SEF-2 und MIBP1
(Applicant
Schüle, Roland
)
Funktionelle Charakterisierung des nukleären Orphan Rezeptors RORß
(Applicant
Schüle, Roland
)
Target basierte Entwicklung neuer Hemmstoffe der Lysin-Dementhylase LSDI und deren Einfluss auf die Regulation des Androgenrezeptors
(Applicants
Jung, Manfred
;
Schüle, Roland
;
Sippl, Wolfgang
)
The novel lysine methyltransferase ILSE1 controls castration-resistant prostate cancer
(Applicant
Schüle, Roland
)
Priority Programmes
Completed projects
Modulation circadianer Regulationsmechanismen durch den nukleären Orphan Rezeptor RZRbeta
(Applicant
Schüle, Roland
)
Reinhart Koselleck Projects
Completed projects
Control of histone demethylase activity: An innovative therapeutic concept to fight hormone refractory prostate cancer
(Applicant
Schüle, Roland
)
Workshops for Early Career Investigators
Current projects
Urologial Diseases in a Aging Society: From Genetic to Medical Csre (UroAgeCare)
(Applicant
Schüle, Roland
)
Research Units
Current projects
FOR 2674: Aging-related epigenetic remodeling in acute myeloid leukemia
(Spokesperson
Lübbert, Ph.D., Michael
)
FOR 5476: UcarE - Urothelial Carcinoma Epigenetics
(Spokesperson
Frew, Ian
)
P5: Dissection of KMT9 biology in urothelial carcinoma
(Applicant
Schüle, Roland
)
The role of the histone demethylase LSD1 in the pathogenesis of AML
(Applicants
Pahl, Heike L.
;
Schüle, Roland
)
Completed projects
FOR 2438: Cell Plasticity in Colorectal Carcinogenesis
(Spokesperson
Greten, Florian R.
)
Collaborative Research Centres
Completed projects
Assembly and signal-mediated regulation of the androgen receptor/LSD1 histone demethylation complex
(Project Head
Schüle, Roland
)
Central Tasks of the Collaborative Research Centre
(Project Head
Schüle, Roland
)
Characterisation of the lysine methyltransferases KMT9 and KMT10
(Project Head
Schüle, Roland
)
Control of adipogenesis by the signal-regulated INHAT-repressor NIR
(Project Head
Schüle, Roland
)
Funktionelle Charakterisierung des Androgenrezeptor Koaktivatorproteins FHL2
(Project Head
Schüle, Roland
)
SFB 992: Medical Epigenetics (MEDEP) - From Basic Mechanisms to Clinical Applications
(Spokesperson
Schüle, Roland
)
Strategien zur gezielten Modulation der transkriptionellen Aktivität des Tumorsuppressorproteins WT1
(Project Head
Schüle, Roland
)
The KMT9 protein machinery is a novel chromatin writer
(Project Head
Schüle, Roland
)
The novel arginine methyltransferase PRMT10 controls tumor growth and metastatic disease
(Project Head
Schüle, Roland
)
Clusters of Excellence
Completed projects
EXC 294: Centre for Biological Signalling Studies (bioss) - From Analysis to Synthesis
(Spokesperson
Reth, Michael
)
Clusters of Excellence (ExStra)
Current projects
EXC 2189: CIBSS - Centre for Integrative Biological Signalling Studies
(Spokespersons
Driever, Wolfgang
;
Hunte, Carola
;
Kleine-Vehn, Jürgen
;
Weber, Wilfried
)
