Medizinische Hochschule Hannover
Leibniz Forschungslaboratorien für Biotechnologie
und künstliche Organe (LEBAO)
Address
Carl-Neuberg-Straße 1
30625 Hannover
Deutschland
GERiT
This institution in GERiT
30625 Hannover
Projects
Research Grants
Current projects
Molecular characterization and pharmacological suppression of pulmonary arterial hypertension
(Applicants
Olmer, Ruth
;
Seyfried, Salim
)
Completed projects
Comparative investigation of host immune response, graft survival and in vivo differentiation after transplantation of undifferentiated embryonic stem cells (ESCs), ESC-derived mesendodermal cardiomyocyte precursors and ESC-derived cardiomyocytes in a mouse model of acute myocardial ischemia
(Applicant
Martin, Ulrich
)
In vitro organization of human induced pluripotent stem cell-derived cardiovascular cells into vascularized cardiac tissue
(Applicants
Gruh, Ina
;
Martin, Ulrich
)
IPS-Zell-basierte myokardiale Regeneration im Mausmodell
(Applicant
Kutschka, Ingo
)
Klonierung und Charakterisierung porciner Galactose-alpha1,3-Galactose-unabhängiger, xenoreaktiver Zelloberflächenstrukturen
(Applicant
Martin, Ulrich
)
LINE-1-mediated retrotransposition in human pluripotent stem cells: Consequences for genomic stability of hES and hiPS cells and its derivatives
(Applicants
Martin, Ulrich
;
Schumann, Gerald G.
)
Untersuchung potentieller PERV-Transmission auf humane Endothelien in einem Schwein-auf-Javaner-Affen Xenotransplantationsmodell
(Applicant
Martin, Ulrich
)
Priority Programmes
Current projects
EndoSpray – Efficient cell coating of biohybrid lungs by atomization of shear-stress resistant endothelial cells derived from induced pluripotent stem cells
(Applicants
Olmer, Ruth
;
Thiebes, Anja Lena
)
Completed projects
Patient-specific induced pluripotent stem (iPS) cells for endothelialisation of membrane surfaces of implantable biohybrid lung devices
(Applicant
Martin, Ulrich
)
Clinical Research Units
Completed projects
Differentiation of embryonic stem cells into type II alveolar epithelial cells: Identification of key factors for differentiation, proof of functionality and establishment of a preclinical nonhuman primate in vitro model
(Applicant
Martin, Ulrich
)
Ex vivo therapy of PAH utilizing hiPSC derived ECs in a SuNx PAH Rat model and development of an organ specific BMPR2 KO animal model in rat and pig
(Applicants
Hansmann, Georg
;
Martin, Ulrich
;
Wiegmann, Bettina
)
Human iPS cell based myocardial tissue as model of heart failure and cardiac assist device therapy: molecular characterization and identification of therapeutic strategies
(Applicants
Gruh, Ina
;
Heineke, Jörg
)
KFO 123: Lung Transplantation
(Spokesperson
Haverich, Axel
)
KFO 311: Cardiac and pulmonary failure: mechanical unloading andrepair
(Spokesperson
Bauersachs, Johann
)
CRC/Transregios
Completed projects
Preclinical assessment of decellularised (antigen-reduced), gene-modified porcine heart valves
(Project Heads
Büttner, Falk
;
Cebotari, Serghei
;
Haverich, Axel
;
Hilfiker, Andres
;
Martin, Ulrich
;
Niemann, Heiner
)
Clusters of Excellence
Completed projects
EXC 62: From Regenerative Biology to Reconstructive Therapy (REBIRTH)
(Spokespersons
Haverich, Axel
;
Thum, Ph.D., Thomas
)
Graduate Schools
Completed projects
GSC 108: Hannover Biomedical Research School (HBRS)
(Spokesperson
Schmidt, Reinhold Ernst
)
