Universität des Saarlandes
Fachrichtung Pharmazie
Lehrstuhl für Pharmazeutische und Medizinische Chemie
Address
Campus
66123 Saarbrücken
Deutschland
GERiT
This institution in GERiT
66123 Saarbrücken
Projects
Research Grants
Completed projects
Development of allosteric inhibitors of AGC kinases and co-crystallography with the target kinases
(Applicants
Biondi, Ricardo M.
;
Engel, Matthias
)
Development of allosteric inhibitors of protein kinase CK2 with additional inhibitory effect on protein-protein interactions
(Applicant
Engel, Matthias
)
Dual inhibitors of steroid sulfatase and 17beta-hydroxysteroid dehydrogenase Typ 1 as scientific tools and potential drugs for the treatment of endometriosis: Rational design, synthesis and biological evaluation in vitro and in vivo
(Applicants
Frotscher, Martin
;
Laschke, Ph.D., Matthias W.
)
Entwicklung ZNS-aktiver Hemmstoffe der Proteinkinase DYRK1A und Kokristallisation mit dem Targetprotein
(Applicant
Engel, Matthias
)
Lipophilic prodrugs of oligonucleotides: synthesis, properties and conjugates for cellular targeting
(Applicant
Ducho, Christian
)
Muraymycin-type nucleoside antibiotics: studies on target interaction and on bacterial cellular uptake
(Applicant
Ducho, Christian
)
Neue Strukturmotive zur Manipulation der Ladung und zur Einführung von Funktionalität im Rückgrat von DNA-Oligonucleotid-Analoga
(Applicant
Ducho, Christian
)
Collaborative Research Centres
Completed projects
Structural insights into protein-ligand-membrane interactions of the bacterial membrane protein MraY: synthesis and application of chemical probes
(Project Head
Ducho, Christian
)
Major Research Instrumentation
Completed projects
Quadrupol-Hybrid-Massenspektrometer inkl. HPLC-System mit DAD