Julius-Maximilians-Universität Würzburg
Biozentrum
Lehrstuhl für Entwicklungsbiochemie
Address
Am Hubland
97074 Würzburg
Deutschland
GERiT
This institution in GERiT
97074 Würzburg
Projects
Priority Programmes
Completed projects
Charakterisierung WT1-abhängig exprimierter Gene in der Entwicklung des urogenitalen Systems
(Applicant
Gessler, Manfred
)
Functional analysis of KDM6A histone demethylase in the regulation of HSC development and in leukemogenesis
(Applicants
Becker, Matthias
;
Müller, Albrecht M.
)
The role of the miR-26 family in neurogenesis
(Applicants
Becker, Matthias
;
Fischer, Utz
)
Research Grants
Current projects
Crosstalk of the Hippo pathway effector YAP and the Myb-MuvB complex in transcriptional regulation of cell cycle genes
(Applicant
Gaubatz, Stefan
)
Role of TRIM28 and BCOR-ITD in kidney development and the formation of pediatric kidney tumors
(Applicants
Becker, Matthias
;
Gessler, Manfred
)
Completed projects
Analysis of the molecular mechanisms of gene regulation by E2F6 and the functional overlap between E2F6 and the retinoblastoma protein
(Applicant
Gaubatz, Stefan
)
Control of normal and malignant pigment cell development
(Applicant
Schartl, Ph.D., Manfred
)
Determination of the mutation rate in shark
(Applicant
Schartl, Ph.D., Manfred
)
EVOBOOSTER - Impact of transposable elements on gene regulatory networks: application to fast-evolving biological pathways in fish
(Applicant
Schartl, Ph.D., Manfred
)
Evolution of sex determining genes in fishes
(Applicant
Schartl, Ph.D., Manfred
)
Evolution von Geschlechtschromosomen, Geschlechtsbestimmungsystemen und Rekombination und ihre Bedeutung für Speziation und Schutz von Amphibien
(Applicant
Stöck, Matthias
)
Functional analysis of DROSHA and DGCR8 microprocessor mutations as a cause of Wilms tumors
(Applicant
Gessler, Manfred
)
Functional analysis of the Hey bHLH factors in vascular development
(Applicant
Gessler, Manfred
)
Functional analysis of the Hey bHLH factors in vascular development
(Applicant
Gessler, Manfred
)
Functional evolution of pigment synthesis pathways in teleost fish through gen(om)e duplication
(Applicant
Schartl, Ph.D., Manfred
)
Lungfish Mega-Genomes: Analysis of the Largest Vertebrate Genomes and the Evolution of Tetrapod Adaptations
(Applicants
Burmester, Thorsten
;
Meyer, Axel
;
Schartl, Ph.D., Manfred
)
miRNA- und mRNA-Signaturen beim Wilmstumor
(Applicants
Gessler, Manfred
;
Graf, Norbert
;
Lenhof, Hans-Peter
;
Meese, Eckart
)
Polyploid Genome Organization and Evolution of Sturgeons (Acipenseridae)
(Applicant
Schartl, Ph.D., Manfred
)
Posttranscriptional regulation of Dmrt1 during sexual development in Medaka
(Applicants
Herpin, Amaury
;
Schartl, Ph.D., Manfred
)
Role of GAS2L3 in cardiomyocyte proliferation and cytokinesis in vitro and in vivo
(Applicant
Gaubatz, Stefan
)
The role of LIN 9 in early mouse development
(Applicant
Gaubatz, Stefan
)
The role of novel human synMuv-like proteins in gene expression and cell cycle regulation
(Applicant
Gaubatz, Stefan
)
The role of p16INK4a in cellular senescence caused by mitotic stress after loss of Lin9
(Applicant
Gaubatz, Stefan
)
The role of Pcgf6 function in ES cells and at the exit of pluripotency
(Applicant
Becker, Matthias
)
Understanding the cellular inventory of pediatric kidney tumors
(Applicants
Gessler, Manfred
;
Saliba, Antoine-Emmanuel
)
Research Units
Completed projects
Analysis of the Molecular Mechanisms of Gene Regulation by E2F6 and the Functional Overlap between E2F6 and the Retinoblastoma Protein
(Applicant
Gaubatz, Stefan
)
Collaborative Research Centres
Completed projects
Das Drosophila four-jointed Homolog fjx1 und sein Rezeptor
(Project Head
Gessler, Manfred
)
Energiestoffwechsel bei Herzinsuffizienz
(Project Heads
Neubauer, Stefan
;
Schnackerz, Klaus Dieter
)
Function of the Hey and Hes bHLH factors in the vascular system
(Project Head
Gessler, Manfred
)
Identifizierung und Charakterisierung von Kontrollgenen für die Entwicklung der Nieren und des Urogenitalsystems
(Project Head
Gessler, Manfred
)
Interspezifische Interaktion des gynogenetischen Amazonenmollies, Poecilia formosa, mit seinen Wirten und mit Parasiten
(Project Head
Schartl, Ph.D., Manfred
)
Kontrolle der normalen und malignen Pigmentzellentwicklung
(Project Heads
Schartl, Ph.D., Manfred
;
Volff, Jean-Nicolas
)
Protein-Interaktionen am membranständigen Wachstumsfaktorrezeptor Xmrk
(Project Heads
Meierjohann, Svenja
;
Schartl, Ph.D., Manfred
)
Protein-Interaktionen am membranständigen Wachstumsfaktor Rezeptor Xmrk
(Project Heads
Schartl, Ph.D., Manfred
;
Wellbrock, Claudia
)
Regulation der Aktivität des Transkriptionsfaktors E2F4 durch Phosphorylierung
(Project Head
Gaubatz, Stefan
)
CRC/Transregios
Completed projects
Administration of the Transregio and Coordination of Activities
(Project Heads
Eilers, Martin
;
Schartl, Ph.D., Manfred
)
Crosstalk of the retinoblastoma and Ras pathways
(Project Head
Gaubatz, Stefan
)
Identification and characterization of tumor modifier genes for malignant melanoma
(Project Head
Schartl, Ph.D., Manfred
)
Ras-dependent pathways in human cancer
(Project Heads
Gaubatz, Stefan
;
Stiewe, Thorsten
)
DFG Research Centres
Completed projects
Forschungsprofessuren
(Project Head
Lohse, Martin J.
)
Kernzentrum
(Project Head
Lohse, Martin J.
)
Nachwuchsgruppeninstitut
(Project Head
Lohse, Martin J.
)
Öffentlichkeitsarbeit
(Project Head
Lohse, Martin J.
)
Studiengänge
(Project Head
Lohse, Martin J.
)
Undergraduate and Graduate Programs
(Project Heads
Kissler, Stephan
;
Schartl, Ph.D., Manfred
)
Zentrale Verwaltung
(Project Head
Lohse, Martin J.
)
Research Training Groups
Completed projects
GRK 639: The Molecular and Structural Basis of Tumorinstability
(Spokespersons
Gessler, Manfred
;
Müller-Hermelink, Hans-Konrad
)
GRK 1048: Molecular Basis of Organ Development in Vertebrates
(Spokesperson
Schartl, Ph.D., Manfred
)
