Universität des Saarlandes
Fachrichtung Biowissenschaften
Arbeitsgruppe Genetik / Epigenetik
Address
Post Office Box 15 11 50
66041 Saarbrücken
Deutschland
GERiT
This institution in GERiT
66041 Saarbrücken
Projects
Research Grants
Current projects
Design and use of EpiEditors to mitigate alpha-synuclein overload in Parkinson’s disease and related synucleinopathies
(Applicants
Jeltsch, Albert
;
Schulze-Hentrich, Ph.D., Julia M.
)
EpiProspects: Evaluating prospects of epigenome profiling in unsolved syndromal cases
(Applicants
Buchert-Lo, Rebecca
;
Schulze-Hentrich, Ph.D., Julia M.
)
Multidimensional genomic signature of human liver growth and hypertrophy
(Applicants
Hampe, Jochen
;
Seehofer, Daniel
;
Walter, Jörn E.
)
STEP-UP - Single cell transcriptome and epigenome profiling to better understand organ development failure in MRKH patients
(Applicants
Koch, Ph.D., André
;
Rall, K. Katharina
;
Schulze-Hentrich, Ph.D., Julia M.
)
warp’d: Integrating transcriptome and DNA methylome data to discern accelerated from delayed adaptations in the unfolding of Parkinson’s disease
(Applicants
Hentrich, Ph.D., Thomas
;
Schulze-Hentrich, Ph.D., Julia M.
)
Completed projects
Developmental consequences of prenatal exposure to endocrine disruptor chemicals - An investigation of epigenetic mechanisms in the Duisburg Birth Cohort Study
(Applicants
Kumsta, Robert
;
Schölmerich, Axel
)
DNA-Methylation profiling at imprints in healthy children conceived by assisted reproduction (ART)
(Applicants
Diedrich, Klaus
;
Kentenich, H.
;
Neitzel, Heidemarie
;
Walter, Jörn E.
)
Genomisches Imprinting des Igf2-Gens in der Maus: Untersuchungen zur DNA-Methylierung und dem Einfluß potentieller "Silencer"-Elemente
(Applicant
Walter, Jörn E.
)
Genom-weite Analyse epigenetischer DNA- und Chromatin-Modifikationen des Morbus Parkinson
(Applicant
Schulze-Hentrich, Ph.D., Julia M.
)
Sequenzbasierte Analyse der Regulation und Interaktion von imprinteten Genen
(Applicant
Paulsen, Martina
)
Priority Programmes
Completed projects
DNA demethylation reprogramming in the mouse zygote
(Applicant
Walter, Jörn E.
)
DNA-methylation reprogramming during early embryogenesis
(Applicant
Walter, Jörn E.
)
Identification of regulatory elements responsible for genomic imprinting in mammals
(Applicant
Paulsen, Martina
)
SPP 1129: Epigenetics
(Spokespersons
Horsthemke, Bernhard
;
Walter, Jörn E.
)
Major Research Instrumentation
Completed projects
Hochdurchsatz Genom Sequenzierer
Microfluidic real-time PCR
Collaborative Research Centres
Current projects
Sequence specific and functional analysis of oxdative modifications in nucleic acids – implication for epigenetic memory in the mouse
(Project Head
Walter, Jörn E.
)
Completed projects
DNA-methylation pattern formation: mechanistic analysis and mathematical modeling of epigenetic control
(Project Heads
Walter, Jörn E.
;
Wolf, Verena
)
NFDI technical and methodological consortia
Current projects
GHGA – German Human Genome-Phenome Archive
(Spokesperson
Stegle, Ph.D., Oliver
)
