Georg-August-Universität Göttingen
Universitätsmedizin Göttingen
Zentrum Biochemie und Molekulare Zellbiologie
Institut für Zellbiochemie
Address
Humboldtallee 23
37073 Göttingen
Deutschland
GERiT
This institution in GERiT
37073 Göttingen
Projects
Research Grants
Current projects
Autophagic and non-autophagic functions of the S. cerevisiae PROPPINs Atg18, Atg21 and Hsv2
(Applicant
Thumm, Michael
)
Dissecting the co-transcriptional processing of human mitochondrial mRNAs
(Applicant
Tan, Ph.D., Benedict
)
Molecular basis for mitochondrial transcription in Trypanosoma brucei
(Applicant
Hillen, Hauke
)
Completed projects
Analyses of RCF function in supramolecular organization of the mitochondrial respiratory chain
(Applicant
Deckers, Markus
)
Aufklärung des molekularen Mechanismus der Lyse autophagischer Vesikel im Innern der Vakuole von Saccharomyces cerevisiae
(Applicant
Thumm, Michael
)
Dissecting the molecular functions of the ubiquitin-like Atg8 during autophagosome biogenesis in S. cerevisiae
(Applicant
Krick, Roswitha
)
Erkennung und Membraninsertion von nicht-spaltbaren Vorstufenproteinen durch die Carrier-Translokase der mitochondrialen Innenmembran
(Applicant
Rehling, Peter
)
Functions and molecular mechanisms of AP-1 and AP-2 complexes and their subunits
(Applicant
Schu, Peter V.
)
Intracellular membrane lysis: How does Atg15 mediate the lysis of autophagic bodies in S. cerevisiae?
(Applicant
Thumm, Michael
)
Mechanisms and components of mitochondrial turnover and quality control by mitophagy
(Applicants
Rehling, Peter
;
Thumm, Michael
)
Molecular analysis of Shy1/Surf1 function in early steps of cytochrome c oxidase assembly
(Applicant
Rehling, Peter
)
Molecular function of Mdm38 in protein export and biogenesis of respiratory chain complexes of the inner mitochondrial membrane
(Applicant
Rehling, Peter
)
Protein analysis by mass spectrometry
(Applicant
von Figura, Kurt
)
Röntgenstrukturanalyse der IGFII-Bindungsdomäne des M6P/IGFII-Rezeptors und zweier bakterieller Sulfatasen
(Applicant
Usón, Isabel
)
Struktur und Funktion des Formylglycin-generierenden Enzyms (FGE)
(Applicants
Dierks, Thomas
;
Schmidt, Bernhard
)
Untersuchungen zum ER/Golgi unabhängigen Transport vakuolärer Enzyme
(Applicant
Schu, Peter V.
)
Untersuchungen zum Mechanismus der Autophagozytose in der Hefe Saccharomyces cerevisiae
(Applicant
Wolf, Dieter H.
)
Priority Programmes
Current projects
Regulation of the human proteostasis network under mitochondrial protein import stress
(Applicants
Dennerlein, Ph.D., Sven
;
Meiners, Silke
;
Warscheid, Bettina
)
Completed projects
Molecular characterization of autophagosomes from the yeast Saccharomyces cerevisiae
(Applicant
Thumm, Michael
)
Research Units
Current projects
FOR 2848: Nanoscale Architecture and Heterogeneity of the Mitochondrial Inner Membrane
(Spokesperson
Jakobs, Stefan
)
Investigation of the spatial distribution of OXPHOS complex assembly in mammalian cells
(Applicants
Jakobs, Stefan
;
Rehling, Peter
)
Structural basis and organization of human cytochrome c oxidase biogenesis
(Applicant
Hillen, Hauke
)
Completed projects
Molecular analysis of Mdm38 function in mitochondrial protein expression
(Applicant
Rehling, Peter
)
Collaborative Research Centres
Current projects
Interconnections of the mitochondrial translation machinery
(Project Head
Rehling, Peter
)
Mechanisms and interconnections of transcription and ribosome biogenesis in mitochondria
(Project Head
Hillen, Hauke
)
Mitochondria function and turnover in synapses
(Project Heads
Rehling, Peter
;
Urlaub, Henning
)
Completed projects
Central Tasks of the Collaborative Research Centre
(Project Head
Rehling, Peter
)
Characterization of mitochondria-ER contact sites and their role in cellular signalling
(Project Heads
Milosevic, Ira
;
Raimundo, Nuno
)
Die Präsequenz-Translokase der mitochondrialen Innenmembran
(Project Heads
Rehling, Peter
;
Truscott, Kaye N.
)
Molecular Basis of Mitochondrial Cardiomyopathies
(Project Head
Rehling, Peter
)
Präprotein-Translokasen der mitochondrialen Innenmembran und des Intermembranraums
(Project Heads
Pfanner, Nikolaus
;
Rehling, Peter
)
Protein transport along the mitochondria carrier pathway
(Project Head
Rehling, Peter
)
Relationship between organellar contact sites and autophagy in S. cerevisiae
(Project Head
Thumm, Michael
)
Role of AP-1 complex for intracellular protein sorting
(Project Head
Schu, Peter V.
)
SFB 1190: Compartmental Gates and Contact Sites in Cells
(Spokesperson
Rehling, Peter
)
Structural basis of protein transport across the outer membrane of human mitochondria
(Project Head
Hillen, Hauke
)
Structure and dynamics of the mitochondrial presequence translocase
(Project Head
Rehling, Peter
)
Structure and molecular function of the WD-40 repeat containing autophagy proteins Atg18, Atg21 and Hsv2
(Project Heads
Ficner, Ralf
;
Kühnel, Karin
;
Thumm, Michael
)
Topologie und zeitlicher Ablauf des Signaltransduktionsweges der hungerinduzierten Autophagocytose in Saccharomyces cerevisiae
(Project Head
Thumm, Michael
)
What are the mechanistic differences in the biogenesis of Cvt vesicles and autophagosomes?
(Project Head
Thumm, Michael
)
Research Training Groups
Completed projects
GRK 521: Protein-Protein Interactions during Intracellular Transport of Macromolecules
(Spokesperson
Doenecke, Detlef
)
Major Instrumentation Initiatives
Completed projects
Göttingen MINFLUX
Graduate Schools
Completed projects
GSC 226: Göttingen Graduate School for Neurosciences and Molecular Biosciences (GGNB)
(Spokesperson
Ficner, Ralf
)
Clusters of Excellence (ExStra)
Current projects
EXC 2067: Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells (MBExC)
(Spokespersons
Cramer, Patrick
;
Moser, Tobias
;
Steinem, Claudia
)
