Universitätsklinikum Regensburg
Klinik und Poliklinik für Innere Medizin II
Address
Franz-Josef-Strauß-Allee 11
93053 Regensburg
Deutschland
GERiT
This institution in GERiT
93053 Regensburg
Projects
Emmy Noether Independent Junior Research Groups
Completed projects
Die Bedeutung der mitochondrialen Ca2+-Aufnahme während der elektronischen Kopplung für die Energetik und den Redoxstatus in Kardiomyozyten
(Applicant
Maack, Christoph
)
Mechanismen der CAMKII-induzierten Arrhytmien im Herzen
(Applicant
Maier, Lars
)
Research Fellowships
Completed projects
Auswirkungen einer Therapie mit Continuous Positive Airway Pressure auf die kardiorespiratorische Reflexkontrolle bei chronischer Herzinsuffizienz
(Applicant
Arzt, Michael
)
Die Rolle und Bedeutung von Redox-sensitiven Signaltransduktionswegen in der Vermittlung von Aldosteron-induzierten Gefäßschäden
(Applicant
Endemann, Dierk
)
Identifizierung von relevanten Genen für das metabolische Syndrom in Familien mit Adipositas
(Applicant
Bäßler, Andrea
)
Impact of extracorporeal membranoxygenation on the microcirculation and integrity of the gastrointestinal tract
(Applicant
Malfertheiner, Maximilian
)
Research Grants
Current projects
Arrhythmogenic mechanisms of sleep-disordered breathing
(Applicant
Wagner, Stefan
)
Disturbed cardiac sodium homeostasis as a mechanism of ethanol-induced atrial arrhythmias
(Applicants
Mustroph, Julian
;
Neef, Stefan
)
Editing CaMKIIδ As A Therapy For Diabetic Cardiomyopathy
(Applicant
Lebek, Simon
)
GLUT1 is required for hyperglycemia-induced CaMKII activation
(Applicants
Maier, Lars
;
Mustroph, Julian
)
Mitochondrial signalling in non-fibrotic dilated cardiomyopathies: aortic regurgitation- and tachycardia-induced heat failure
(Applicant
Dietl, Alexander
)
Precise Ablation of Pathogenic CaMKIIδ9 as a Therapy for Cardiac Disease
(Applicants
Hegner, Philipp
;
Lebek, Simon
)
Role of redox-activated CaMKII delta and PKA RIalpha in doxorubicine-induced cardiomyopathy
(Applicant
Sag, Can Martin
)
Completed projects
Analysis of immunoregulatory effects of basophils in the T cell transfer model of colitis.
(Applicant
Mack, Matthias
)
Association studies for the identification of susceptibility genes for myocardial infarction
(Applicant
Hengstenberg, Christian
)
Bedeutung der Chemokinrezeptoren CCR2 und CCR5 für die Migration und Funktion regulatorischer T-Zellen
(Applicant
Mack, Matthias
)
Chemokinrezeptorexpression auf Leukozyten als Ziel einer immunmodulatorischen Therapie
(Applicant
Mack, Matthias
)
Gefäßschäden bei Diabetes mellitus: Bedeutung von Salzsensitivität, Aldosteron und oxidativem Stress
(Applicant
Endemann, Dierk
)
Genetik seltener, familiär-gehäufter Formen des Herzinfarktes
(Applicant
Schunkert, Heribert
)
Progress DHF - Mechanisms for the Progression from Diastolic Dysfunction to Diastolic Heart Failure
(Applicant
Maier, Lars
)
Recruitment, activation and effector pathways of basophils in chronic allograft remodeling
(Applicant
Mack, Matthias
)
Regulation und Fuktion der bronchoepithelialen Chemokinrezeptoren CXCR1 und CXCR2 bei der chronisch obstruktiven Lungenerkrankung (COPD
(Applicant
Schulz, Christian
)
The Effect of Exercise on the Pathogenesis of ARVC in a Mouse Model and the Comparability to Patient Specific Cardiac Myocytes from Induced Pulripotent Stem Cells
(Applicants
Hammer, Ph.D., Karin
;
Wagner, Stefan
)
The role of Ca/calmodulin dependent protein kinase II (CaMKII) in the heart for triggering and maintenance of atrial fibrillation in diabetes mellitus
(Applicant
Maier, Lars
)
The role of the MAGUK protein CASK for CaMKII activation in the heart
(Applicants
Maier, Lars
;
Wagner, Stefan
)
Untersuchungen zum Mechanismus und zur funktionellen Bedeutung des Mikrovesikelvermittelten Transfers von Chemokinrezeptoren
(Applicant
Mack, Matthias
)
Clinical Research Units
Completed projects
Basophile Granulozyten als neue Regulatoren einer GvHD und GvT Reaktion
(Applicant
Mack, Matthias
)
Basophils as modulators of humoral and cellular allo-immune responses
(Applicant
Mack, Matthias
)
Bedeutung des sarkolemmalen Natrium Kanals für kardiale Kontraktilität und Arrhythmogenese
(Applicant
Maier, Lars
)
Impact of drugs targeting tumor metabolism on human CD8 T cell effector functions
(Applicants
Herr, Wolfgang
;
Renner-Sattler, Kathrin
)
Heisenberg Professorships
Completed projects
Heisenbergprofessur für kardiovaskuläre experimentele Elektrophysiologie und Bildgebung
(Applicant
Maier, Lars
)
Heisenberg Grants
Current projects
Precise Gene Editing To Fight Cardiovascular Diseases
(Applicant
Lebek, Simon
)
Collaborative Research Centres
Completed projects
Cardio- and nephroprotective mechanisms of SGLT2 inhibition
(Project Heads
Maier, Lars
;
Schweda, Frank
;
Wagner, Stefan
)
Development of fibrocytes and their contribution to collagen production
(Project Head
Mack, Matthias
)
Effects of CaMKII on arrhythmogenesis in heart failure
(Project Heads
Maier, Lars
;
Sossalla, Samuel
)
Relevance of inflammation and fibrosis for renal regeneration
(Project Head
Mack, Matthias
)
Strategien zur Blockade des Chemokinrezeptors CCr5 als Angriffspunkt einer HIV-suppressiven Therapie
(Project Heads
Mack, Matthias
;
Schlöndorff, Detlef
)
WBP Fellowship
Current projects
The role of cardiac macrophages for ventricular arrhythmias
(Applicant
Pabel, Steffen
)
Completed projects
Precise gene editing as a therapeutic approach in cardiac disease
(Applicant
Lebek, Simon
)
CRC/Transregios
Current projects
Cardio- and nephroprotective mechanisms of SGLT2 inhibition
(Project Heads
Maier, Lars
;
Tauber, Philipp
;
Wagner, Stefan
)
Phenotypic and functional characterization of pro-fibrotic and pro-regenerative T cells in models of renal fibrosis
(Project Head
Mack, Matthias
)
Heisenberg Fellowships
Completed projects
Bedeutung der Ca/Calmodulin-abhängigen Kinase (CaMKII) für Hypertrophie, Herzinsuffizienz und Arrhythmien
(Applicant
Maier, Lars
)
Priority Programmes
Current projects
Fatal Hemostatic Complications in Artificial Lungs: From Understanding to Prevention - Understanding of Shear-Induced Clotting Mechanisms for Prevention of Thrombosis
(Applicants
Krenkel, Lars
;
Lehle, Karla
;
Müller, Thomas
)
Research Training Groups
Completed projects
GRK 438: Vascular Biology in Medicine
(Spokesperson
Siess, Wolfgang
)
