Universitätsklinikum Heidelberg
Hautklinik
Address
Im Neuenheimer Feld 440
69120 Heidelberg
Deutschland
GERiT
This institution in GERiT
69120 Heidelberg
Projects
Research Grants
Current projects
Analyzing the function of the endocytic receptor DEC205 in vitro and in vivo during delivery and presentation of antigens in brain endothelial cells.
(Applicant
Mahnke, Karsten
)
Dysbiosis development in mice with deficient IL-17 signaling in keratinocytes
(Applicants
Kurschus, Ph.D., Florian
;
Regen, Tommy
)
Immune complex-directed cell migration: mechanisms and relevance
(Applicant
Schäkel, Knut
)
Uncovering the Mechanisms Driving Virus-Induced Central Nervous System Disease.
(Applicant
Kurschus, Ph.D., Florian
)
Completed projects
Analyse der Anwendbarkeit von T-Zell-Rezeptorpeptiden zur T-Zell-gerichteten Immunsuppression mittels dendritischer Zellen
(Applicant
Enk, Alexander
)
Functional specialization of proinflammatory dendritic cells in psoriasis
(Applicant
Schäkel, Knut
)
Molekulare Mechanismen der intrazellulären Zielsteuerung des Antigenrezeptors DEC-205 (CD205) in Dendritischen Zellen
(Applicant
Mahnke, Karsten
)
Role of Regulatory T cells for the pathogenesis of Autoimmune Blistering Diseases
(Applicants
Enk, Alexander
;
Hadaschik, Eva
)
The pathogenic role of EBI2 in skin inflammation
(Applicant
Kurschus, Ph.D., Florian
)
Toleranzinduktion durch molekulares Targeting von Antigenen zu Dendritischen Zellen in vivo
(Applicant
Mahnke, Karsten
)
Collaborative Research Centres
Completed projects
Analyse der Funktion regulatorischer T-Zellen beim malignen Melanom und ihre therapeuthische Bedeutung
(Project Head
Enk, Alexander
)
(A) Real time quantitative PCR (B) Frequenzbestimmung und funktionelle Analyse spezifischer zellulärer Immunreaktionen
(Project Heads
Enk, Alexander
;
Löhr, Hanns
)
Funktionelle Analyse der Chemotaxis, der Adhäsion und der Migration von regulatorischen T-Zellen im murinen Model des allergischen Kontaktekzems
(Project Head
Mahnke, Karsten
)
Funktionelle Analyse regulatorischer T-Zellen in humanen und murinen Krankheitsmodellen
(Project Head
Enk, Alexander
)
MOG specific T and B cell-autoimmunity
(Project Heads
Holz, Andreas
;
Kurschus, Ph.D., Florian
;
Wekerle, Hartmut
)
Rage as regulatory molecule in cutaneous chronic inflammation
(Project Heads
Enk, Alexander
;
Gebhardt, Christoffer
)
Studies on the immune function of human slan-dendritic cells in psoriasis
(Project Head
Schäkel, Knut
)
Tissue bank for inflammatory diseases
(Project Heads
Enk, Alexander
;
Lasitschka, Felix
)
Untersuchungen zur Funktion tolerogener dendritischer Zellen und humaner regulatorischer T-Zellen in Tumorpatienten in vivo
(Project Head
Enk, Alexander
)
Research Fellowships
Completed projects
Defining the Langerhans cell precursor niche within the follicular microenvironment
(Applicant
Döbel, Thomas
)
CRC/Transregios
Current projects
Central tasks
(Project Head
Enk, Alexander
)
Defining therapeutic responsiveness in patients with bullous pemphigoid by immunophenotyping
(Project Heads
Enk, Alexander
;
Kommoss, Katharina
;
Ramcke, Torben
)
Role of T cell subsets in the pathogenesis of autoimmune blistering disease
(Project Heads
Enk, Alexander
;
Hadaschik, Eva
)
The role of neutrophils during induction of tolerance in contact hypersensitivity reactions
(Project Head
Mahnke, Karsten
)
TRR 156: The skin as sensor and effector orchestrating local and systemic immunity
(Spokesperson
Enk, Alexander
)
Completed projects
Immune complex mediated and IgG Fc receptor-dependent recruitment of leukocytes into the skin
(Project Heads
Olaru, Florina
;
Schäkel, Knut
)
Targets and mediators of IL-17 in mouse models of psoriasis and skin infection
(Project Heads
Kurschus, Ph.D., Florian
;
Waisman, Ari
)
WBP Fellowship
Current projects
Deciphering the neuro-immunological role of the IL-31/IL-31 receptor axis in atopic dermatitis
(Applicant
Ramcke, Torben
)
Prognosis estimation in malignant melanoma based on changes in tumor genome
(Applicant
Ginter, Katharina
)
