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Institution
Albert-Ludwigs-Universität Freiburg
Institut für Biologie III
Address
Schänzlestraße 1
79104 Freiburg
Deutschland
GERiT
This institution in GERiT
79104 Freiburg
Projects
Priority Programmes
Current projects
Cross-talk and extensive rewiring of CRISPR-Cas systems with the cellular regulatory machinery in cyanobacteria
(Applicant
Hess, Wolfgang R.
)
Early Determinants of Heterocyst Differentiation in Multicellular Cyanobacteria
(Applicants
Backofen, Rolf
;
Hess, Wolfgang R.
)
Evolution of the regulatory networks governing developmental adaptations and acclimation responses in Charophycean green algae towards plant life on land
(Applicant
Hess, Wolfgang R.
)
The role of small proteins, peptides and dual function transcripts in cyanobacteria
(Applicant
Hess, Wolfgang R.
)
Unravelling the intricate regulation of the expression program of T4-like cyanophages
(Applicants
Lindell, Ph.D., Debbie
;
Steglich, Claudia
)
Completed projects
A light-triggered behavioural switch in cyanobacterial motility
(Applicant
Wilde, Annegret
)
Asymmetric division of the zygote in Arabidopsis thaliana
(Applicant
Laux, Thomas
)
Functional dissection of presenilins in a C. elegans in vivo model
(Applicant
Baumeister, Ralf
)
Genetische und Molekulare Analyse der Morphogenese von Maiswurzeln
(Applicant
Feix, Günter
)
Identification and function of regulatory RNA in the phototropic model organism Synechocystis sp. PCC 6803
(Applicants
Hess, Wolfgang R.
;
Wilde, Annegret
)
Natural functions of CRISPR-Cas systems in Cyanobacteria
(Applicant
Wilde, Annegret
)
Regulatory RNAs in the hfq-deficient oxyphototroph Prochlorococcus sp.
(Applicant
Steglich, Claudia
)
Systematische und faunistische Bearbeitung antarktischer Kamptozoen POLARSTERN-Fahrt ANT VIII/4
(Applicant
Emschermann, Peter
)
Research Grants
Current projects
An integrated investigation of regulatory RNAs and their interacting proteins in bacteria models
(Applicants
Hess, Wolfgang R.
;
Voß, Björn
)
Antagonizing unfolded protein response of the endoplasmic reticulum by the endoribonuclease ENDU-2/ENDOU
(Applicant
Qi, Ph.D., Wenjing
)
Cost/benefit of dinitrogen fixation and the ecosystem consequences
(Applicants
Hellweger, Ferdinand
;
Köhler, Jan
)
Completed projects
A protodermal miR394 signal defines a region of stem cell competence in the Arabidopsis shoot meristem
(Applicant
Laux, Thomas
)
Aufklärung der Funktion des Blaulichtrezeptors Phototropin in Chlamydomonas
(Applicant
Beck, Christoph Friedrich
)
Bestimmung von Strukturelementen der tRNA, die beteiligt sind an der Aminosäure-Erkennung durch Aminoacyl-tRNA Synthetasen
(Applicant
Igloi, Gabor
)
CRISPR/Cas systems in cyanobacteria, their involvement in cell differentiation and potential for metabolic manipulation
(Applicant
Hess, Wolfgang R.
)
Etablierung von Entwicklungsdomänen im Embryo von Arabidopsis thaliana
(Applicant
Laux, Thomas
)
European Plant Embryology Consortium
(Applicants
Jürgens, Gerd
;
Laux, Thomas
;
Nodine, Michael
;
Scheres, Ben
;
Weijers, Ph.D., Dolf
)
Feedback communication between mother plant and embryo regulating early embryo development in Arabidopsis thaliana
(Applicant
Laux, Thomas
)
Functional analysis of the WUSCHEL HOMEOBOX (WOX) gene family in Arabidopsis
(Applicant
Laux, Thomas
)
Funktionelle Analyse des cyanobakteriellen Phytochroms Cph2
(Applicant
Wilde, Annegret
)
Funktionen der C. elegans Linkerhistone
(Applicant
Schulze, Ekkehard
)
Funktionsanalyse des WUSCHEL Gens bei der Entwicklung des Sproßmeristems von Arabidopsis thaliana
(Applicant
Laux, Thomas
)
Funktionsanalyse eines plastidären Chaperons in Chlamydomonas
(Applicant
Beck, Christoph Friedrich
)
Genetic mechanisms of petal size regulation in Arabidopsis thaliana
(Applicant
Laux, Thomas
)
Hydrocarbon production in genetically engineered cyanobacteria
(Applicant
Hess, Wolfgang R.
)
Identification and function of regulatory RNA in the phototrophic model organism Synechocystis sp. PCC 6803
(Applicants
Hess, Wolfgang R.
;
Wilde, Annegret
)
Identifizierung von transformationsrelevanten Jun-Zielgenen
(Applicant
Kruse, Ulrich
)
Initiation of shoot meristem stem cells during Arabidopsis embryogenesis
(Applicant
Laux, Thomas
)
INTEGRATED ANALYSIS OF STEM CELL FUNCTION IN PLANT GROWTH AND DEVELOPMENT (ERA-PG 059)
(Applicant
Laux, Thomas
)
Mechanism and function of non standard circadian clock systems in cyanobacteria
(Applicants
Axmann, Ilka Maria
;
Wilde, Annegret
)
Novel Cyanobacterial Toxin-Antitoxin Systems
(Applicant
Hess, Wolfgang R.
)
Optical properties of microbial cells ans sensing the light direction in phototaxis
(Applicants
Korvink, Jan Gerrit
;
Wilde, Annegret
)
Phage-dependent gene expression dynamics in host-phage systems
(Applicant
Steglich, Claudia
)
Post-translational protein arginylation in plants: localization, dynamics and function
(Applicant
Igloi, Gabor
)
Regulation of the asymmetric division of the Arabidopsis thaliana zygote by the WRKY2 pathway
(Applicant
Laux, Thomas
)
Röntgenmikroskopische Analyse von Protein- und Nucleinsäureverteilungen in eukaryotischen Zellkernen und Chromosomen
(Applicant
Rudolph, Dietbert
)
Role of DNA methylation in cyanobacteria – From gene expression control to DNA repair and back
(Applicants
Hagemann, Martin
;
Hess, Wolfgang R.
)
Stem cell regulation by the transcription factor WOX5 in the Arabidopsis thaliana root meristem
(Applicant
Laux, Thomas
)
The function of the IRM protein Kirre in sensory pathway formation
(Applicant
Fischbach, Karl-Friedrich
)
The role of WIH1/2 peptides in the transition from somatic to sporogenic fate in plants
(Applicant
Laux, Thomas
)
The role of WOX genes regulating apical embryo patterning
(Applicant
Laux, Thomas
)
Toxic small RNAs that regulate essential genes in Salmonella, a combined experimental and computational approach
(Applicant
Georg, Jens
)
Transcriptional Regulation of Zygote Asymmetry in Arabidopsis thaliana
(Applicant
Laux, Thomas
)
What are the mechanisms used to prevent the incorporation of natural toxic amino acids into proteins?
(Applicant
Igloi, Gabor
)
Research Units
Current projects
Control of the cyanobacterial day-night metabolism by a biological clock system
(Applicant
Wilde, Annegret
)
FOR 2816: The Autotrophy-Heterotrophy Switch in Cyanobacteria: Coherent Decision-Making at Multiple Regulatory Layers
(Spokesperson
Forchhammer, Karl
)
Novel regulators and interactions within the regulatory networks controlling the autotrophy -heterotrophy switch in cyanobacterial carbon metabolism
(Applicant
Hess, Wolfgang R.
)
Completed projects
Analysis of CRISPR-Cas systems in Cyanobacteria
(Applicant
Hess, Wolfgang R.
)
Analysis of prophyrin-mediated signaling pathways for the control of nuclear genes by the chloroplast
(Applicant
Beck, Christoph Friedrich
)
Collaborative Research Centres
Current projects
Light-dependent dynamics in the assembly of the cyanobacterial motility machinery
(Project Head
Wilde, Annegret
)
Ribonucleoprotein complex dynamics controlling LINE-1 retrotransposition and stress responses
(Project Head
Baumeister, Ralf
)
Completed projects
ceh-16/engrailed kompartimentiert die Epidermis des Fadenwurms Caenorhabditis elegans
(Project Head
Baumeister, Ralf
)
Entwicklung synaptischer Übertragungsdynamik und cortikaler Netzwerkeigenschaften: eine in vitro Studie unter in vivo-nahen Bedingungen
(Project Heads
Aertsen, Adrianus
;
Egert, Ulrich
;
Heck, Detlef
;
Rotter, Stefan
)
Festlegung der Position von Organen in Arabidopsis thaliana
(Project Head
Laux, Thomas
)
Functional genetic Analysis of Parkinsons Disease-related Genes in Caenorhabditis Elegans
(Project Head
Baumeister, Ralf
)
Funktion des PAO/CoREST Transkriptionsrepressor-Komplexes für die Nervensystemdiffernzierung und die Suppression von Presenilin Mutanten
(Project Head
Baumeister, Ralf
)
Influence of columnar and laminar synaptic connectivity patterns on spontaneous and stimulus-induced network dynamics in rat sensory neocortex
(Project Heads
Aertsen, Adrianus
;
Boucsein, Clemens
;
Rotter, Stefan
)
Interaktion von Proteinkomponenten transkriptional aktiver Komplexe (TAC) aus Chloroplasten beim Edieren und Spleißen plastidärer Transkripte
(Project Head
Kössel, Hans
)
Kontrolle der späten Lungendifferenzierung in der Maus
(Project Head
Sippel, Albrecht E.
)
Molekularbiologie der Photosynthese und Photosynthese-abhängiger Prozesse in Prochlorococcus marinus
(Project Head
Hess, Wolfgang R.
)
Molekulare Analyse der Morphogenese der Dauerlarve von Caenorhabditis elegans
(Project Heads
Grossbach, Ulrich
;
Schulze, Ekkehard
)
Molekulare Faktoren für axonale Wegfindung, Erkennung der Zielregion und Synaptogenese im optischen Lobus von Drosophila
(Project Head
Fischbach, Karl-Friedrich
)
Non-cellautonomous role of the endoribonuclease ENDU-2/ENDOU/PP11 in tumorigenesis and invasion
(Project Head
Baumeister, Ralf
)
Protein interactions and modifications determine the activity of a major regulator of neural transcription, the POU protein UNC-86
(Project Head
Baumeister, Ralf
)
Protein modifications and interactions of the FOXO/DAF-16 and mTORC mediated stress response
(Project Head
Baumeister, Ralf
)
Regulation von Stammzellen im Sproßmeristen von Arabidopsis Thaliana
(Project Head
Laux, Thomas
)
Role of Parkinson's Disease-associated genes in polarized sorting and synapse dynamics modulating behavioral plasticity
(Project Head
Baumeister, Ralf
)
Serviceprojekt für Molekularbiologie und Proteinchemie
(Project Heads
Bessler, Wolfgang G.
;
Igloi, Gabor
;
Schiltz, Emil
)
Stem cell regulation in Arabidopsis plant apical meristems
(Project Head
Laux, Thomas
)
Structure und function of conserved chloroplast open reading frames from Synechocystis sp. PCC 6803
(Project Heads
Grimm, Bernhard
;
Wilde, Annegret
)
Struktur und Funktion des ZWILLE Proteinkomplexes von Arabidopsis
(Project Head
Laux, Thomas
)
Transkriptionsfaktorregulation während der in vitro-Differenzierung von myelopoetischen Zellen aus embryonalen Stammzellen der Maus
(Project Head
Sippel, Albrecht E.
)
Zelltypspezifischer Aufbau und molekulare Funktion eines eukaryontischen Transkriptionsenhancers
(Project Head
Sippel, Albrecht E.
)
Zelluläre Funktionen der Wechselwirkungen der IRRE C-RST und Kirre Zelladhäsionsmoleküle
(Project Head
Fischbach, Karl-Friedrich
)
Major Research Instrumentation
Completed projects
Flow cytometer with up to five lasers, spectral analyses and auto-sampling
Konfokales Laserscanning-Mikroskop
TIRF Microscope with laser illumination and two EMCCD cameras
TIRF Mikroscop with laser illuminaion and two CMOS cameras
Clinical Research Units
Completed projects
Identification and functional characterization of new components of TOR signalling in C. elegans
(Applicant
Neumann-Haefelin, Elke
)
Research Fellowships
Completed projects
Reverse electron transfer involving a butyrate-induced membrane complex during syntrophic growth of Syntrophomonas wolfei
(Applicant
Kung, Johannes
)
Research Training Groups
Current projects
GRK 2344: MeInBio - BioInMe: Exploration of spatio-temporal dynamics of gene regulation using high-throughput and high-resolution methods
(Spokesperson
Vogel, Tanja
)
Completed projects
GRK 434: Biochemistry of Enzymes
(Spokesperson
Fuchs, Georg
)
GRK 843: Mechanisms of neuronal signal transduction - from protein to network
(Spokesperson
Fakler, Bernd
)
GRK 1104: From Cells to Organs: Molecular Mechanisms of Organogenesis
(Spokesperson
Neubüser, Annette
)
GRK 1305: Signal Systems in Plant Model Organisms
(Spokesperson
Palme, Klaus
)
International Research Training Groups
Completed projects
GRK 1384: Enzymes and Multienzyme Complexes Acting on Nucleic Acids
(Spokesperson
Friedhoff, Peter
)
Graduate Schools
Completed projects
GSC 4: Molecular Cell Research in Biology and Medicine (MOBILMED)
(Spokesperson
Borner, Christoph
)
Clusters of Excellence
Completed projects
EXC 294: Centre for Biological Signalling Studies (bioss) - From Analysis to Synthesis
(Spokesperson
Reth, Michael
)
EXC 1086: BrainLinks-BrainTools
(Spokesperson
Burgard, Wolfram
)
Clusters of Excellence (ExStra)
Current projects
EXC 2189: CIBSS - Centre for Integrative Biological Signalling Studies
(Spokespersons
Driever, Wolfgang
;
Hunte, Carola
;
Kleine-Vehn, Jürgen
;
Weber, Wilfried
)
Additional Information
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