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Institution
Universitätsklinikum Essen
Klinik für Neurologie
Address
Hufelandstraße 55
45147 Essen
Deutschland
GERiT
This institution in GERiT
45147 Essen
Projects
Research Grants
Current projects
Involvement of the human cerebellum in reinforcement learning via its connection with the ventral tegmental area (VTA)
(Applicants
Bingel, Ulrike
;
Brand, Matthias
;
Timmann-Braun, Dagmar
)
Promoting Excellence in Medicine: The University Medicine Essen Clinician Scientist Academy (UMEA)
(Applicant
Führer-Sakel, Dagmar
)
Sensing of extracellular matrix in motor circuit remodelling: a novel target for neuroplasticity-promoting stroke therapies?
(Applicant
Dzyubenko, Ph.D., Egor
)
Completed projects
Altered visceral and psychological stress signal processing in visceral hyperalgesia: Role of central pain processing and local inflammation in the gut.
(Applicant
Elsenbruch, Sigrid
)
Cerebellar control of overarm throwing.
(Applicant
Timmann-Braun, Dagmar
)
Dekompressive Kraniektomie beim embolischen Mediainfarkt. Auswirkungen auf Perfusion, Zellschädigung und Infarktentwicklung
(Applicant
Dörfler, Arnd
)
Die Bedeutung des menschlichen Kleinhirns für assoziative Lernvorgänge
(Applicant
Timmann-Braun, Dagmar
)
Die pathophysiologische Rolle regulatorischer T Zellen beim akuten ischämischen Schlaganfall
(Applicants
Kleinschnitz, Christoph
;
Wiendl, Heinz
)
Effects of experimental endotoxemia on the neural processing of visceral and somatosensory stimuli
(Applicants
Benson, Sven
;
Elsenbruch, Sigrid
)
Impact of NKG2D signaling on T cell and NK cell function in cerebral ischemia
(Applicants
Kleinschnitz, Christoph
;
Meuth, Sven G.
)
In vivo Assessment of the Cerebellum by Novel MRI Techniques and Application to Hereditary Ataxias: Morphological, Pathoanatomical and Clinical Aspects
(Applicants
Deistung, Andreas
;
Timmann-Braun, Dagmar
)
Kognitive Modulation der Schmerzverarbeitung und Placebowirksamkeit untersucht mit fMRT
(Applicant
Büchel, Christian
)
Long-term follow-up after cerebro-vascular events of different aetiology
(Applicant
Diener, Hans-Christoph
)
Long-term follow-up after cerebro-vascular events of different aetiology
(Applicant
Diener, Hans-Christoph
)
Mechanisms underlying training-related motor improvement in cerebellar ataxia.
(Applicant
Timmann-Braun, Dagmar
)
NADPH oxidases in ischemic stroke: cellular sources and pharmacological translation
(Applicant
Kleinschnitz, Christoph
)
Neuroprotection in platinum-induced neurotoxicity
(Applicant
Hagenacker, Tim
)
Pathophysiologie zerebellärer Bewegungsstörungen: Motorische Kontrolle des Greifens und Manipulierens
(Applicants
Hermsdörfer, Joachim
;
Timmann-Braun, Dagmar
)
Prognose von fokalen Läsionen des Kleinhirns im Kindes- und Jugendalter
(Applicant
Timmann-Braun, Dagmar
)
Proprioceptive training for patients with degenerative cerebellar ataxia.
(Applicant
Timmann-Braun, Dagmar
)
Strukturelle und funktionelle Magnetresonanztomographie des Kleinhirns im 7 Tesla Magnetfeld
(Applicant
Timmann-Braun, Dagmar
)
The interference of experimental pain and cognition in patients suffering from chronic pain
(Applicant
Forkmann, Katarina
)
The role of the cerebellum for feedback processing
(Applicants
Minnerop, Martina
;
Peterburs, Jutta
;
Timmann-Braun, Dagmar
)
Tumor Nekrose Faktor-alpha vermittelte Modulation ektoper neuronaler Aktivität nach Nervenläsionen und deren funktionelle Relevanz für die Schmerzentwicklung
(Applicant
Schäfers, Maria Anna
)
Research Fellowships
Completed projects
Blood brain barrier disruption and edema formation: Regulative mechanisms and effects of cortical speading depression (CSD) triggered matrix metalloproteinase (MMP) activation
(Applicant
Haerter, Katharina
)
Die Bedeutung des Spinalganglions für die Entstehung von Neuropathieschmerz: Auswirkungen mechanischer und Zytokin-induzierter Stimulation auf die Freisetzung spinaler Neurotransmitter und die Entstehung von Spontanaktivität peripherer und zentraler Nozizeptoren
(Applicant
Schäfers, Maria Anna
)
Neuronale Grundlagen kognitiv-affektiver Prozesse der Schmerzwahrnehmung am Beispiel der Fibromyalgie
(Applicant
Wiech, Katja
)
Heisenberg Professorships
Completed projects
Medizinische Psychologie
(Applicant
Elsenbruch, Sigrid
)
Research Units
Current projects
Enhancing cerebellar-dependent motor learning by focalized tDCS
(Applicant
Timmann-Braun, Dagmar
)
FOR 2879: ImmunoStroke: From immune cells to stroke recovery
(Spokesperson
Liesz, Arthur
)
FOR 5429: Modulation of brain networks for memory and learning by transcranial electrical brain stimulation: A systematic, lifespan approach
(Spokesperson
Flöel, Agnes
)
ImmunoStroke: From Immune cells to stroke recovery. Plasma-kallikrein mediated modulation of T cells and microglia responses during long-term stroke recovery.
(Applicants
Casas Guijarro, Ana I.
;
Hansen, Wiebke
;
Kleinschnitz, Christoph
)
Standardization of animal models and outcome parameters
(Applicants
Langhauser, Friederike
;
Llovera, Gemma
)
Completed projects
Central tasks of all subprojects of the Research Unit
(Applicant
Rief, Ph.D., Winfried
)
Constribution of the human cerebellum to extinction learning and renewal
(Applicant
Timmann-Braun, Dagmar
)
Coordination Funds
(Applicant
Kleinschnitz, Christoph
)
Effects of emotional context on placebo analgesia and nocebo hyperalgesia in a visceral pain model
(Applicant
Elsenbruch, Sigrid
)
Exploiting learning mechanisms to maximize analgesic treatment outcome
(Applicant
Bingel, Ulrike
)
FOR 1328: Expectation and Conditioning as Basic Processes of the Placebo and Nocebo Response
(Spokesperson
Rief, Ph.D., Winfried
)
Neural mechanisms of learning and extinction in human visceral pain
(Applicant
Elsenbruch, Sigrid
)
WBP Position
Completed projects
First-in-class neuroprotective therapy in acute ischemic stroke, poststroke cognitive impairment and mechanistically related diseases by network pharmacology of common signalling targets
(Applicant
Casas Guijarro, Ana I.
)
Heisenberg Fellowships
Completed projects
Medizinische Psychologie
(Applicant
Elsenbruch, Sigrid
)
Clinical Trials
Current projects
COlchicine for prevention of Vascular Inflammation in Non-CardioEmbolic stroke - a randomised clinical trial (CONVINCE). German Extension
(Applicants
Jöckel, Karl-Heinz
;
Weimar, Christian
)
EFFects of EXPosure and Cognitive-behavioural Therapy for chronic BACK pain (EFFECT-BACK)
(Applicant
Glombiewski, Julia
)
Completed projects
Coronary Artery Bypass graft surgery in patients with Asymptomatic Carotid Stenosis (CABACS): a randomized controlled trial
(Applicant
Weimar, Christian
)
Collaborative Research Centres
Current projects
Appetitive and aversive pain-related learning in health and chronic back pain
(Project Heads
Bingel, Ulrike
;
Forkmann, Katarina
;
Schmidt, Katharina
)
Focus Group Neuroimaging and Genetics
(Project Heads
Axmacher, Nikolai
;
Kumsta, Robert
;
Quick, Harald
;
Timmann-Braun, Dagmar
)
From Pavlov to Pain: Extinction Learning in Visceral pain
(Project Heads
Elsenbruch, Sigrid
;
Icenhour, Adriane
)
The contribution of the cerebellum to extinction: intrinsic mechanisms and cerebello-cerebral interactions
(Project Heads
Quick, Harald
;
Timmann-Braun, Dagmar
)
The impact of chronic inflammation on fear extinction
(Project Heads
Elsenbruch, Sigrid
;
Engler, Harald
)
Completed projects
Kallikrein/Kinin-System mediated cell/cell-interactions at the blood-brain-barrier during cerebral ischemia
(Project Head
Kleinschnitz, Christoph
)
Multi-site communication underlying contextual manipulation of the attentional demands of pain
(Project Head
Bingel, Ulrike
)
CRC/Transregios
Current projects
Behavioral and neural effects of practitioner communication on speech perception, treatment expectation, and treatment outcome
(Project Heads
Blank, Helen
;
Wiech, Katja
)
Central scientific project: Neuroimaging
(Project Heads
Bingel, Ulrike
;
Büchel, Christian
;
Spisak, Ph.D., Tamas
)
Central Tasks
(Project Head
Bingel, Ulrike
)
Communicating the science of treatment expectations – from healthcare professionals to patients and back
(Project Heads
Benson, Sven
;
Bingel, Ulrike
;
Hartmann, Ph.D., Helena
)
Dynamic changes in expectation and perception within and across pain modalities
(Project Heads
Elsenbruch, Sigrid
;
Kleine-Borgmann, Julian
)
How does the cerebellum contribute to placebo hypoalgesia and nocebo hyperalgesia?
(Project Head
Timmann-Braun, Dagmar
)
Local TH transport and action in ischaemic brain injury
(Project Heads
Führer-Sakel, Dagmar
;
Kleinschnitz, Christoph
;
Langhauser, Friederike
)
Neurobiological mechanisms and temporal dynamics of negative treatment expectations in an animal model of sickness behavior
(Project Heads
Engler, Harald
;
Heiß-Lückemann, Laura
;
Schedlowski, Manfred
)
Preoperative expectation optimization to reduce postoperative pain and disability after hip surgery
(Project Heads
Elsenbruch, Sigrid
;
Klinger, Regine
)
The mechanisms underlying the formation, updating, and generalization of expectations and their effect on pain
(Project Head
Bingel, Ulrike
)
TRR 289: Treatment Expectation - The impact of expectation on health outcome
(Spokesperson
Bingel, Ulrike
)
Completed projects
Role of platelets in tissue remodelling and functional recovery after experimental cerebral ischaemia
(Project Heads
Kleinschnitz, Christoph
;
Langer, Harald
)
Priority Programmes
Completed projects
Die Bedeutung des menschlichen Kleinhirns für assoziative Lernvorgänge
(Applicant
Timmann-Braun, Dagmar
)
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