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Institution
Universitätsklinikum Bonn (AöR)
Universitäts-Augenklinik Bonn
Address
Ernst-Abbe-Straße 2
53127 Bonn
Deutschland
GERiT
This institution in GERiT
53127 Bonn
Projects
Priority Programmes
Current projects
Pathway engineering to optimize homology dependent therapeutic genome editing at the ABCA4 locus in photoreceptors
(Applicants
Busskamp, Ph.D., Volker
;
Stieger, Knut
)
Completed projects
Adaptive optics imaging and micro-stimulation to yield in vivo single-cell biomarker of retinal function and dysfunction in the human retina.
(Applicant
Harmening, Wolf
)
Barrier free chromatic pupillometry in children from infancy on. A novel biomarker to quantify outer and inner retinal function in inherited retinal disorders as a measure of therapeutic benefit after gene therapy.
(Applicant
Lorenz, Birgit
)
Effects of lipofuscin accumulation on lysosomal functions of human RPE cells
(Applicant
Kopitz, Jürgen
)
Fundus Autofluorescence imaging in Age-related Macular degeneration (FAM-Study) using confocal scanning laser ophthalmoscopy
(Applicant
Holz, Frank G.
)
Fundus Autofluorescence imaging in Age-related Macular degeneration (FAM-Study) using confocal scanning laser ophthalmoscopy
(Applicant
Foja, Christian
)
SPP 1088: Age-Related Macular Degeneration
(Spokesperson
Kirchhof, Bernd
)
Symposia, workshops, and sabbaticals of the Priority Program "Age-Related Macular Degeneration
(Applicant
Kirchhof, Bernd
)
Symposia, workshops, and sabbaticals of the Priority Program "Age-Related Macular Degeneration"
(Applicant
Holz, Frank G.
)
Research Grants
Current projects
Deciphering the elemental building blocks of visual appearance
(Applicant
Harmening, Wolf
)
Developing a molecular surgical approach to repair and stabilize cone function in retinitis pigmentosa
(Applicant
Busskamp, Ph.D., Volker
)
In vivo mapping of foveal photoreceptors in retinal health and disease
(Applicant
Harmening, Wolf
)
Maintaining retinal ganglion cells within human retinal organoids by implementing a vascular system.
(Applicant
Busskamp, Ph.D., Volker
)
Natural History and Structural Consequences of a Diseased Bruch’s Membrane in Pseudoxanthoma Elasticum (PXE)
(Applicant
Pfau, Kristina
)
Completed projects
Analyse der retinalen Langzeitmorbidität bei ehemaligen Extremfrühgeborenen in Abhängigkeit vom Stadium der Frühgeborenenretinopathie. Eine prospektive explorative Kohortenstudie mittels morphologischer und funktioneller in vivo Diagnostik
(Applicant
Lorenz, Birgit
)
Bilateral cataract following unilateral exposure to ultraviolet radiation. Ocular immune cross-talk and immunmodulation between left and right eye.
(Applicants
Meyer, Ph.D., Linda Maren
;
Wegener, Alfred
)
Das Okulo-Aurikulo-Vertebrale Spektrum (OAVS) - Klinische Aufarbeitung und molekulargenetische Analyse eines heterogenen Krankheitsspektrums
(Applicant
Lorenz, Birgit
)
Laser System for Optogenetic Stimulation for the subcellular investigation of Neural Networks
(Applicants
Busskamp, Ph.D., Volker
;
Czarske, Jürgen W.
)
Longitudinal Genotype-Phenotype Correlation in Congenital and Early Onset Hereditary Retinal Degenerations as a Prerequisite for Future Gene Therapeutic Studies.
(Applicant
Lorenz, Birgit
)
Morphologic and functional characterization of macular telangiectasia type 2
(Applicant
Tzaridis, Simone
)
Mutual influence of tumor cells, extracellular matrix and macrophages in intraocular murine melanoma
(Applicant
Herwig-Carl, Martina
)
Verbesserte Früherkennung von Augenhintergrundveränderungen bei Frühgeborenen und Neugeborenen mit perinatalen Erkrankungen zur Verhütung schwerer Sehstörungen bis hin zur Blindheit und zur Optimierung neonatologischer und neuropädiatrischer Maßnahmen
(Applicant
Lorenz, Birgit
)
Independent Junior Research Groups
Completed projects
Advanced adaptive optics instrumentation for ophthalmic imaging and function testing: the single cell approach to visual function and dysfunction
(Applicant
Harmening, Wolf
)
Research Fellowships
Completed projects
Deep-learning based phenotyping and prediction of disease progression in geographic atrophy secondary to age-related macular degeneration
(Applicant
Pfau, Maximilian
)
Investigation of long-wavelength fundus autofluorescence
(Applicant
Gliem, Martin
)
In vivo- and in vitro-investigations regarding the impact of hypoxia on ocular tumors (retinoblastoma and melanoma) in correlation to tumor cell motility.
(Applicant
Herwig-Carl, Martina
)
Local dysregulation of the alternative complement pathway in retinal pigment epithelium as a model for age-related macular degeneration
(Applicant
Herrmann, Ph.D., Philipp
)
Multimodal imaging, packing geometry and autofluorescence properties of human retinal pigment epithelium cells as a function of age and age-related macular degeneration
(Applicant
Ach, Thomas
)
Probing retinal and neural mechanisms of vision by hyperacute optical stimulation of single photoreceptor cells
(Applicant
Harmening, Wolf
)
WBP Fellowship
Current projects
Structure function correlation of high resolution retinal imaging in early age-related macular degeneration and physiological aging
(Applicant
Goerdt, Lukas
)
The associations of inflammation biomarkers with the risk of developing age-related macular degeneration
(Applicant
Larsen, Petra
)
Completed projects
Microstructural determinants of dark adaptation and effects of retinoid administration in age-related macular degeneration
(Applicant
Pfau, Kristina
)
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