Project Details
Projekt
LC/SEC-ESI-Massenspektrometer
Subject Area
Polymer Research
Term
Funded in 2008
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 85665398
„The Barner-Kowollik group (presently at the University of New South Wales in Sydney, Australia) currently works on 6 parallel topics employing LC/SEC-ESI-MS technology and has extensive experience in SEC/LC-ESI-MS on polymer systems. SEC/LC-ESI-MS is one of Prof. Barner-Kowollik’s key research instruments. He has recently accepted a full professorship (‘Lehrstuhl für Präparative Makromolekulare Chemie’) at Karlsruhe University (starting 1/7/2008) in the context of the ‘Exzellenzinitiative’, which necessitates the acquisition of such an instrument for this institution. The sought equipment is an essential part of the research themes detailed in the main application. Typically, the LC/SEC-ESI-MS is in use every day for 8 hs in the Barner-Kowollik group. The acquired mass spectrometer poses as a headstone analytical instrument for work conducted at the research group, be it mechanistic investigations, determination of kinetic parameters or synthetic work with small and large polar molecules. The soft ionization method of electrospray leaves the polymer molecules intact and thus allows a detailed mapping of them. No other method provides equally soft ionization in conjunction with on-line SEC/LC leading to a high quality imaging of single polymer chains. The interfacing of LC/SEC with mass spectrometry is important for providing a pre-separation of the polymer sample, which enters the ESI-MS system ‘slice-by-slice’. Such a pre-separation, which also includes the analysis of the polymer with refractive index and UV/Vis detectors, significantly increases the sensitivity of the obtained mass spectra (leading to less ion suppression effects) and allows for the quantitative determination of molecular weight distributions. The SEC-ESI-MS instrument will be purely employed for research purposes (100 %).“
DFG Programme
Major Research Instrumentation
Instrumentation Group
1700 Massenspektrometer
Applicant Institution
Karlsruher Institut für Technologie (KIT)
Campus Süd (aufgelöst)
Campus Süd (aufgelöst)
